{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T18:13:05Z","timestamp":1764785585628,"version":"3.41.2"},"reference-count":34,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2025,2,24]],"date-time":"2025-02-24T00:00:00Z","timestamp":1740355200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,7,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>Acute decompensated heart failure (HF) can progress to cardiogenic shock, and patients with cancer are at an increased risk of HF compared with patients without cancer. However, limited data exist on outcomes of patients admitted for HF-related cardiogenic shock (HF-CS) with cancer vs. without cancer.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>Adult patients admitted for HF-CS between 2014 and 2020 were identified using the National Readmission Database. Propensity score matching (PSM) was used to match 1 patient with cancer to 10 patients without cancer. Primary outcomes were in-hospital death, major bleeding, and thrombotic complications. Exploratory outcomes were 90-day readmission rates among patients who survived initial hospitalization. Temporal trends were also explored. Of the 137 316 admissions for HF-CS, 7306 (5.3%) had active cancer. After PSM, patients with cancer had increased odds of in-hospital death [odds ratio (OR) 1.12, 95% confidence interval (CI) 1.06\u20131.18], thrombotic complications (OR 1.12, 95% CI 1.03\u20131.21), and major bleeding (OR 1.23, 95% CI 1.17\u20131.31) compared with patients without cancer, with risks differing by cancer type. In exploratory analyses, rates of readmission were similar for patients with and without cancer. From 2014 to 2020, patients with cancer had no significant change in in-hospital mortality (Ptrend = 0.43), while patients without cancer had decreased mortality over time (Ptrend &amp;lt; 0.001).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Among patients admitted for HF-CS, patients with cancer are at increased risk of in-hospital death, thrombotic complications, and major bleeding compared with patients without cancer. Future studies are needed to guide nuanced evaluation and management of this population to improve outcomes.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjacc\/zuaf027","type":"journal-article","created":{"date-parts":[[2025,2,24]],"date-time":"2025-02-24T17:56:11Z","timestamp":1740419771000},"page":"318-326","source":"Crossref","is-referenced-by-count":1,"title":["Outcomes of patients with cancer admitted with heart failure\u2013associated cardiogenic shock"],"prefix":"10.1093","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4995-4863","authenticated-orcid":false,"given":"Olivia","family":"Liu","sequence":"first","affiliation":[{"name":"Division of Cardiology, Department of Medicine, New York University Grossman School of Medicine , 550 First Ave., New York, NY 10016, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven","family":"Soo","sequence":"additional","affiliation":[{"name":"Department of Medicine, New York University Long Island School of Medicine , Mineola, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle","family":"Bloom","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine, New York University Grossman School of Medicine , 550 First Ave., New York, NY 10016, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose","family":"Alvarez-Cardona","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine, New York University Grossman School of Medicine , 550 First Ave., New York, NY 10016, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jason N","family":"Katz","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine, New York University Grossman School of Medicine , 550 First Ave., New York, NY 10016, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard K","family":"Cheng","sequence":"additional","affiliation":[{"name":"Division of Cardiology, University of Washington , Seattle, WA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4889-7454","authenticated-orcid":false,"given":"Eric H","family":"Yang","sequence":"additional","affiliation":[{"name":"UCLA Cardio-Oncology Program, Division of Cardiology, Department of Medicine, University of California Los Angeles , Los Angeles, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3006-6380","authenticated-orcid":false,"given":"Orly","family":"Leiva","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine, New York University Grossman School of Medicine , 550 First Ave., New York, NY 10016, USA"},{"name":"Section of Cardiology\u2014Heart Failure, Department of Medicine, University of Chicago , Chicago, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,2,24]]},"reference":[{"key":"2025070309270462100_zuaf027-B1","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.jacc.2022.04.042","article-title":"Cardiovascular disease risk among cancer survivors: the Atherosclerosis Risk In Communities (ARIC) study","volume":"80","author":"Florido","year":"2022","journal-title":"J Am Coll Cardiol"},{"key":"2025070309270462100_zuaf027-B2","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1253\/circj.CJ-23-0838","article-title":"Shared and reciprocal mechanisms between heart failure and cancer-an emerging concept of heart-cancer axis","volume":"88","author":"Kadowaki","year":"2024","journal-title":"Circ J"},{"key":"2025070309270462100_zuaf027-B3","doi-asserted-by":"crossref","first-page":"2272","DOI":"10.1002\/ejhf.2029","article-title":"Common mechanistic pathways in cancer and heart failure. 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