{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T16:58:43Z","timestamp":1789750723947,"version":"4.0.1"},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2025,2,28]],"date-time":"2025-02-28T00:00:00Z","timestamp":1740700800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,7,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>Only limited epidemiological data exist from national or international prospective multicentre registries covering the whole spectrum of cardiogenic shock (CS) aetiologies.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>A national prospective multicentre observational study, CZECH-SHOCK, was conducted in 15 main tertiary care centres in Czechia over a 12 month period from March 2023 to February 2024. A total of 418 patients with a median age of 70 (interquartile range 59\u201376) years were enrolled. The majority of patients was males (69.6%). A newly developed heart failure was observed in 76.8% patients, and acute myocardial infarction complicated by CS was the most frequent cause of a CS episode (56.7%). Mechanical circulatory support devices were utilized in 28.2% of cases. A 30 day mortality was 39.5%. In a multivariate analysis, six independent factors were associated with a higher 30 day mortality: age [odds ratio (OR) per 10-year increase: 1.78, 95% confidence interval (CI): 1.45\u20132.19], history of coronary artery disease (OR: 2.38, 95% CI: 1.41\u20134.30), history of chronic obstructive pulmonary disease (OR: 2.58, 95% CI: 1.27\u20135.25), Society for Cardiovascular Angiography and Interventions class on admission (OR per one class increase: 1.64, 95% CI: 1.27\u20132.11), renal replacement therapy during in-hospital stay (OR: 2.46, 95% CI: 1.32\u20134.59), and new mechanical ventilation after admission (OR: 4.58, 95% CI: 2.50\u20138.39).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Acute myocardial infarction complicated by CS still represents the most frequent cause of CS episodes. The in-hospital mortality of patients with CS remains high, despite frequent utilization of haemodynamic support and organ replacement therapies.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjacc\/zuaf034","type":"journal-article","created":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T22:11:51Z","timestamp":1741126311000},"page":"359-363","source":"Crossref","is-referenced-by-count":4,"title":["Clinical characteristics, management, and predictors of mortality: results from the national prospective cardiogenic shock registry (CZECH-SHOCK)"],"prefix":"10.1093","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7486-7705","authenticated-orcid":false,"given":"Michal","family":"Pazdernik","sequence":"first","affiliation":[{"name":"Department of Cardiology, Institute for Clinical and Experimental Medicine (IKEM) , Videnska 1958\/9, Prague 140 21 ,","place":["Czechia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petr","family":"Ostadal","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Second Medical School, Charles University, University Hospital Motol , V Uvalu 84\/1, Prague 150 06 ,","place":["Czechia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiri","family":"Seiner","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Hospital Liberec , Husova 1430\/34, Liberec 460 01 ,","place":["Czechia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Pudil","sequence":"additional","affiliation":[{"name":"2nd Department of Medicine\u2014Department of Cardiovascular Medicine, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague , U Nemocnice 499\/2, Prague 128 08 ,","place":["Czechia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Chaloupka","sequence":"additional","affiliation":[{"name":"1st Internal Clinic of Cardio-angiology, St Anne's University Hospital and Faculty of Medicine, Masaryk University , Pekarska 664\/53, Brno 602 00 ,","place":["Czechia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Novak","sequence":"additional","affiliation":[{"name":"1st Internal Clinic of Cardio-angiology, St Anne's University Hospital and Faculty of Medicine, Masaryk University , Pekarska 664\/53, Brno 602 00 ,","place":["Czechia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Lichnerova","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Disease, University Hospital in Ostrava , 17. listopadu 1790\/5, Ostrava 708 00 ,","place":["Czechia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Radek","family":"Pelouch","sequence":"additional","affiliation":[{"name":"1st Department of Internal Medicine, Cardioangiology, Faculty of Medicine in Hradec Kralove, Charles University in Prague, and University Hospital Hradec Kralove , Sokolsk\u00e1 581, Hradec Kr\u00e1lov\u00e9 500 05 ,","place":["Czechia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dagmar","family":"Vondrakova","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Second Medical School, Charles University, University Hospital Motol , V Uvalu 84\/1, Prague 150 06 ,","place":["Czechia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aneta","family":"Dvorakova","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Na Homolce Hospital , Roentgenova 37\/2, Prague 150 30 ,","place":["Czechia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Foral","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Heart Centre, Hospital \u010cesk\u00e9 Bud\u011bjovice , B. N\u011bmcov\u00e9 585\/54, a.s., Ceske Budejovice 370 01 ,","place":["Czechia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ales","family":"Kovarik","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Heart Centre, Hospital \u010cesk\u00e9 Bud\u011bjovice , B. N\u011bmcov\u00e9 585\/54, a.s., Ceske Budejovice 370 01 ,","place":["Czechia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomas","family":"Hnat","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Second Medical School, Charles University, University Hospital Motol , V Uvalu 84\/1, Prague 150 06 ,","place":["Czechia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmad","family":"Zohoor","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Regional Hospital , Bezru\u010dova 1190\/19, Karlovy Vary 360 01 ,","place":["Czechia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"Pocarovsky","sequence":"additional","affiliation":[{"name":"Deparment of Cardiology, Regional Hospital , Kyjevsk\u00e1 44, Pardubice 530 03 ,","place":["Czechia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aneta","family":"Hainzova","sequence":"additional","affiliation":[{"name":"Deparment of Cardiology, Regional Hospital , Kyjevsk\u00e1 44, Pardubice 530 03 ,","place":["Czechia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Matejka","sequence":"additional","affiliation":[{"name":"Deparment of Cardiology, Regional Hospital , Kyjevsk\u00e1 44, Pardubice 530 03 ,","place":["Czechia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ondrej","family":"Sirotek","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Hospital and Faculty of Medicine Pilsen , E. Bene\u0161e 1128\/13, Pilsen 301 00 ,","place":["Czechia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Valerianova","sequence":"additional","affiliation":[{"name":"3rd Department of Internal Medicine, First Faculty of Medicine, Charles University, General University Hospital , U Nemocnice 499\/2, Prague 128 08 ,","place":["Czechia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Vojtisek","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Regional Hospital Usti nad Labem , Socialni pece 3316, Usti nad Labem 400 11 ,","place":["Czechia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Precek","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine I\u2014Cardiology, University Hospital Olomouc and Faculty of Medicine and Dentistry, Palacky University Olomouc , Zdravotniku 248\/7, Olomouc 779 00 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