{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T06:24:31Z","timestamp":1774679071511,"version":"3.50.1"},"reference-count":26,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2025,3,14]],"date-time":"2025-03-14T00:00:00Z","timestamp":1741910400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,5,16]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>The aim of this study is to examine the trends and outcomes of mechanical circulatory support (MCS) device use among patients with mechanical complications of acute myocardial infarction (AMI).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>Using data from the National Inpatient Sample (a large admirative database in the USA) years 2016\u201320, we identified AMI admissions (ST-elevation and non-ST-elevation myocardial infarction) with mechanical complications (ventricular septal defect, free wall rupture, or papillary muscle rupture). Among 4 450 219 AMI patients, 7025 (0.2%) had a mechanical complication of which 3115 patients (44.3%) received at least one MCS device. There was a rising trend in MCS use (39.3% in 2016 to 48.9% in 2020, Ptrend = 0.02), but there was no corresponding reduction in the incidence of in-hospital mortality (36.9% in 2016 vs. 43.4% in 2020, Ptrend = 0.75). There was no significant difference in in-hospital mortality between those who received MCS vs. those who did not (48.4 vs. 34.5%, respectively).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In this large observational analysis of AMI hospitalizations, mechanical complications were rare and associated with very high in-hospital mortality. Although the use of MCS has increased, in-hospital mortality rates remain high even among patients who received MCS. Further investigations are needed to clarify the role of MCS devices among patients with mechanical complications of AMI.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ehjacc\/zuaf039","type":"journal-article","created":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T08:44:01Z","timestamp":1741855441000},"page":"288-294","source":"Crossref","is-referenced-by-count":5,"title":["Outcomes with mechanical circulatory support devices among patients with mechanical complications of acute myocardial infarction"],"prefix":"10.1093","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7847-7867","authenticated-orcid":false,"given":"Ahmed M","family":"Younes","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Riverside Shore Memorial Hospital , Onancock, VA ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed K","family":"Mahmoud","sequence":"additional","affiliation":[{"name":"St. Elizabeth Medical Center, Department of Internal Medicine, Boston University , Boston, MA ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ibrahim","family":"Kamel","sequence":"additional","affiliation":[{"name":"St. Elizabeth Medical Center, Department of Internal Medicine, Boston University , Boston, MA ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linus","family":"Williams","sequence":"additional","affiliation":[{"name":"Department of Medicine, Beth Israel Lahey Medical Center , Burlington, MA ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8991-1104","authenticated-orcid":false,"given":"Ahmed","family":"Maraey","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University of Toledo Medical Center , Toledo, OH ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahmoud","family":"Khalil","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University of Connecticut Medical Center , Farmington, CT ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed","family":"Elzanaty","sequence":"additional","affiliation":[{"name":"Wake Forest School of Medicine , Department Of Cardiology, Winston Salem, NC ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodrigo","family":"Bagur","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine, Western University , London, ON ,","place":["Canada"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdulla A","family":"Damluji","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Inova Center of Outcomes Research , Falls Church, VA ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacqueline E","family":"Tamis-Holland","sequence":"additional","affiliation":[{"name":"Miller Family Heart, Vascular & Thoracic Institute, Cleveland Clinic , Cleveland, OH ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9853-7591","authenticated-orcid":false,"given":"Islam Y","family":"Elgendy","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Gill Heart and Vascular Institute, University of Kentucky , 900 S. 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