{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T09:46:55Z","timestamp":1793094415312,"version":"4.5.0"},"reference-count":19,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:00:00Z","timestamp":1756339200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,23]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>This study aims to determine the safety and effectiveness of the KronoSafe\u00ae permanent pacemaker adapter for temporary cardiac pacing (TCP) with active-fixation leads (TCPAFLs).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>This was a multicentre, prospective, descriptive clinical investigation involving a medical device (ClinicalTrials.gov identifier: NCT05351658). Between January 2023 and December 2024, all consecutive patients who underwent implantation of a temporary active-fixation pacemaker were included. The devices were secured using the KronoSafe\u00ae adapter throughout the period of use. Complications during TCPAFL were recorded, and R-wave sensing, lead impedance, and pacing threshold were determined every 48\u2005h. Thirty patients (10 with atrioventricular block, nine TAVI, five alcohol septal ablations, two slow atrial fibrillations, two bradycardia\u2013tachycardia syndrome, and two pacemaker infections) who required TCP were included. Two centres participated in the study. The mean duration of TCP was 7.8\u2005days (maximum 22\u2005days), with 79.2% of the time spent in the cardiology ward. One complication (3%) was recorded, due to accidental traction of the system associated with an episode of agitation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Temporary cardiac pacing with active-fixation leads using the KronoSafe\u00ae adapter is safe and effective, and its use can be extended outside the intensive care unit.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ehjacc\/zuaf111","type":"journal-article","created":{"date-parts":[[2025,8,26]],"date-time":"2025-08-26T11:28:50Z","timestamp":1756207730000},"page":"732-738","source":"Crossref","is-referenced-by-count":1,"title":["A novel device for temporary cardiac stimulation using permanent pacemaker generators and active-fixation leads: the TEMPACE multicentre prospective study"],"prefix":"10.1093","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6766-3103","authenticated-orcid":false,"given":"Raimundo","family":"Vicente-Miralles","sequence":"first","affiliation":[{"name":"Intensive Care Unit, Dr. Balmis General University Hospital, Alicante ,","place":["Spain"]},{"name":"Institute for Health and Biomedical Research (ISABIAL) , Alicante ,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2101-8678","authenticated-orcid":false,"given":"Nuria","family":"Rivas-G\u00e1ndara","sequence":"additional","affiliation":[{"name":"Arrhythmia Unit, Cardiology Department, Hospital Universitario Vall d`Hebron , Barcelona ,","place":["Spain"]},{"name":"Ciber Cardiovascular, Instituto de Salud Carlos III, Madrid ,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6999-278X","authenticated-orcid":false,"given":"Pablo","family":"Jord\u00e1n Marchite","sequence":"additional","affiliation":[{"name":"Arrhythmia Unit, Cardiology Department, Hospital Universitario Vall d`Hebron , Barcelona ,","place":["Spain"]},{"name":"Ciber Cardiovascular, Instituto de Salud Carlos III, Madrid ,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8843-9370","authenticated-orcid":false,"given":"Raquel","family":"Adeli\u00f1o","sequence":"additional","affiliation":[{"name":"Arrhythmia Unit, Cardiology Department, Hospital Universitario Vall d`Hebron , Barcelona ,","place":["Spain"]},{"name":"Ciber Cardiovascular, Instituto de Salud Carlos III, Madrid ,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9078-2178","authenticated-orcid":false,"given":"Mar\u00eda \u00c1ngeles","family":"Carmona","sequence":"additional","affiliation":[{"name":"Arrhythmia Unit, Cardiology Department, Hospital Universitario Vall d`Hebron , Barcelona ,","place":["Spain"]},{"name":"Ciber Cardiovascular, Instituto de Salud Carlos III, Madrid ,","place":["Spain"]},{"name":"Universitat Aut\u00f2noma de Barcelona , Barcelona ,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00f3nica","family":"D\u00edaz Barranco","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, Dr. Balmis General University Hospital, Alicante ,","place":["Spain"]},{"name":"Institute for Health and Biomedical Research (ISABIAL) , Alicante ,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7352-6597","authenticated-orcid":false,"given":"Alicia Ascensi\u00f3n","family":"Iba\u00f1ez Criado","sequence":"additional","affiliation":[{"name":"Institute for Health and Biomedical Research (ISABIAL) , Alicante ,","place":["Spain"]},{"name":"Cardiology Department, Dr Balmis General University Hospital , Alicante ,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8480-0835","authenticated-orcid":false,"given":"Juan Miguel","family":"Ruiz Nodar","sequence":"additional","affiliation":[{"name":"Institute for Health and Biomedical Research (ISABIAL) , Alicante ,","place":["Spain"]},{"name":"Cardiology Department, Dr Balmis General University Hospital , Alicante ,","place":["Spain"]},{"name":"Department of Clinical Medicine, Miguel Hernandez University , Ctra. Alicante-Valencia N 332, San Juan de Alicante, Alicante 03550 ,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4541-6064","authenticated-orcid":false,"given":"Mar\u00eda","family":"Ajo Ferrer","sequence":"additional","affiliation":[{"name":"Institute for Health and Biomedical Research (ISABIAL) , Alicante ,","place":["Spain"]},{"name":"Cardiology Department, Dr Balmis General University Hospital , Alicante ,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8040-0527","authenticated-orcid":false,"given":"Amaya","family":"Garc\u00eda-Fern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Institute for Health and Biomedical Research (ISABIAL) , Alicante ,","place":["Spain"]},{"name":"Cardiology Department, Dr Balmis General University Hospital , Alicante ,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5309-0562","authenticated-orcid":false,"given":"Vicente","family":"Bertomeu-Gonzalez","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine, Miguel Hernandez University , Ctra. Alicante-Valencia N 332, San Juan de Alicante, Alicante 03550 ,","place":["Spain"]},{"name":"Cardiology Department, Hospital Clinica Benidorm , Avenida Alfonso Puchades 8, 03501 Benidorm, Alicante ,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2255-3530","authenticated-orcid":false,"given":"Juan Gabriel","family":"Mart\u00ednez Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Institute for Health and Biomedical Research (ISABIAL) , Alicante ,","place":["Spain"]},{"name":"Cardiology Department, Dr Balmis General University Hospital , Alicante ,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,8,28]]},"reference":[{"key":"2026031015540218700_zuaf111-B1","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1016\/j.chest.2018.11.026","article-title":"Complications and outcomes of temporary transvenous pacing: an analysis of 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international consensus document on how to prevent, diagnose, and treat cardiac implantable electronic device infections-endorsed by the Heart Rhythm Society (HRS), the Asia Pacific Heart Rhythm Society (APHRS), the Latin American Heart Rhythm Society (LAHRS), International Society for Cardiovascular Infectious Diseases (ISCVID) and the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS)","volume":"22","author":"Blomstr\u00f6m-Lundqvist","year":"2020","journal-title":"Europace"},{"key":"2026031015540218700_zuaf111-B5","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1378\/chest.59.5.498","article-title":"Temporary cardiac pacing: technique and 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cardiac pacing and cardiac resynchronization therapy [published correction appears in Europace. 2022 Apr 5;24(4):699. doi: 10.1093\/europace\/euac023.]","volume":"24","author":"Glikson","year":"2022","journal-title":"Europace"},{"key":"2026031015540218700_zuaf111-B9","author":"Oliver Sala"},{"key":"2026031015540218700_zuaf111-B10","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1136\/heart.89.2.209","article-title":"Prolonged temporary cardiac pacing using subcutaneous tunnelled active-fixation permanent pacing leads","volume":"89","author":"Lever","year":"2003","journal-title":"Heart"},{"key":"2026031015540218700_zuaf111-B11","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1016\/j.ejcts.2005.02.040","article-title":"Pacemaker dependent patients with device infection\u2014a modified approach","volume":"27","author":"Rastan","year":"2005","journal-title":"Eur J Cardiothorac 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