{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T16:56:21Z","timestamp":1774889781188,"version":"3.50.1"},"reference-count":52,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T00:00:00Z","timestamp":1761696000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,3,16]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Patients with acute pulmonary embolism (PE) may present with cardiac arrest, overt or impending cardiogenic shock and\/or severe respiratory insufficiency. Immediate evaluation and management of these patients require high clinical suspicion along with (bedside) imaging to confirm the diagnosis, targeted haemodynamic and\/or respiratory support, appropriate anticoagulant treatment, and in many cases reperfusion therapy. The immediate treatment decision-making is largely driven by local expertise and resources and should be guided by the individual patient\u2019s characteristics such as cardiopulmonary comorbidities, risk of bleeding and location, extent and haemodynamic impact of the clot. Over the past years, treatment options for patients with severe PE have expanded substantially. For instance, several new catheter-guided reperfusion therapies have emerged and experience with circulatory mechanical support has increased. Along with the rise of new interventional therapies has come the introduction of expert multidisciplinary pulmonary embolism (EXPERT-PE) care teams, composed of multidisciplinary specialists involved in treating severe acute PE. This model of care provides a platform for rapid decisions on individualized treatment strategies, combining expert opinion from all involved specialties, setting the quality standards for modern local and regional equity PE care, and forming the base for future research in this area. Clinical decisions should be evidence-based where possible, and incorporate the individual patient\u2019s and their carer\u2019s preferences, values, and priorities, as well as those of the managing clinicians and care team. In this review, we summarize the evidence for the introduction of EXPERT-PE care teams and provide a practical manual for their successful implementation.<\/jats:p>","DOI":"10.1093\/ehjacc\/zuaf141","type":"journal-article","created":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T12:54:27Z","timestamp":1761656067000},"page":"151-161","source":"Crossref","is-referenced-by-count":3,"title":["Rationale for and approach to establishing a multidisciplinary acute pulmonary embolism expert care team"],"prefix":"10.1093","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9961-0754","authenticated-orcid":false,"given":"Frederikus A","family":"Klok","sequence":"first","affiliation":[{"name":"Department of Medicine\u2014Thrombosis and Hemostasis, Leiden University Medical Center , Albinusdreef 2, 2300 RC, Leiden ,","place":["the Netherlands"]},{"name":"Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg University , Langenbeckstra\u00dfe 1 55131 Mainz ,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Sharp","sequence":"additional","affiliation":[{"name":"School of Medicine, University College Dublin and The Mater Misericordiae Hospital , Dublin ,","place":["Ireland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ingo","family":"Ahrens","sequence":"additional","affiliation":[{"name":"Augustinerinnen Hospital Cologne and Medical Faculty, University of Freiburg , Dublin ,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3955-9528","authenticated-orcid":false,"given":"Milica","family":"Aleksic","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Hospital Medical Center Bezanijska kosa , Belgrade ,","place":["Serbia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0163-792X","authenticated-orcid":false,"given":"Fionnuala","family":"Ni Ainle","sequence":"additional","affiliation":[{"name":"School of Medicine, University College Dublin , Belfield, Dublin 4 ,","place":["Ireland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2618-347X","authenticated-orcid":false,"given":"Stefano","family":"Barco","sequence":"additional","affiliation":[{"name":"Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg University , Langenbeckstra\u00dfe 1 55131 Mainz ,","place":["Germany"]},{"name":"Department of Vascular Medicine, University Hospital Zurich , Zurich ,","place":["Switzerland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8214-3010","authenticated-orcid":false,"given":"Laurent","family":"Bertoletti","sequence":"additional","affiliation":[{"name":"D\u00e9partement of M\u00e9decine Vasculaire et Th\u00e9rapeutique, F-CRIN INNOVTE Network, Universit\u00e9 Jean Monnet Saint-\u00c9tienne, CHU Saint-\u00c9tienne, Mines Saint-Etienne, INSERM, SAINBIOSE U1059, CIC 1408 , Saint-Etienne ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brent","family":"Keeling","sequence":"additional","affiliation":[{"name":"Professor of Surgery, Emory University School of Medicine , Atlanta, GA ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0611-7376","authenticated-orcid":false,"given":"Karl","family":"Fengler","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Heart Center Leipzig , Leipzig ,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie","family":"Helms","sequence":"additional","affiliation":[{"name":"Strasbourg University (UNISTRA); INSERM (French National Institute of Health and Medical Research), UMR 1260, Regenerative Nanomedicine (RNM)\u2014FHU TARGET , Strasbourg ,","place":["France"]},{"name":"Medical Intensive Care Unit\u2014NHC, Strasbourg University Hospital , Strasbourg ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Jim\u00e9nez","sequence":"additional","affiliation":[{"name":"Respiratory Department, Hospital Ram\u00f3n y Cajal and Instituto Ram\u00f3n y Cajal de Investigaci\u00f3n Sanitaria IRYCIS , Madrid ,","place":["Spain"]},{"name":"Medicine Department, Universidad de Alcal\u00e1 , Madrid ,","place":["Spain"]},{"name":"CIBER Enfermedades Respiratorias (CIBERES) , Madrid ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irene M","family":"Lang","sequence":"additional","affiliation":[{"name":"Division of Hematology and Hemostaseology, Department of Medicine I, Universit\u00e4tskliniken, Medical University of Vienna , Wien"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mandy N","family":"Lauw","sequence":"additional","affiliation":[{"name":"Department of Hematology, Erasmus University Medical Center , Rotterdam ,","place":["The Netherlands"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1777-2045","authenticated-orcid":false,"given":"Roberto","family":"Lorusso","sequence":"additional","affiliation":[{"name":"Department of Cardio-Thoracic Surgery, Maastricht University Medical Centre (MUMC) , Maastricht, the Netherlands"},{"name":"Cardiovascular Research Institute Maastricht (CARIM) , Maastricht ,","place":["The Netherlands"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ignacio","family":"Martin-Loeches","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Medicine, Multidisciplinary Intensive Care Research Organization (MICRO), St. James\u2019 Hospital , Dublin ,","place":["Ireland"]},{"name":"School of Medicine, Trinity College Dublin , Dublin ,","place":["Ireland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lilian J","family":"Meijboom","sequence":"additional","affiliation":[{"name":"Amsterdam Cardiovascular Sciences, Pulmonary Hypertension and Thrombosis , Amsterdam ,","place":["The Netherlands"]},{"name":"Department of Radiology and Nuclear Medicine, Amsterdam UMC location Vrije Universiteit Amsterdam , Amsterdam ,","place":["The Netherlands"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicolas","family":"Meneveau","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Hospital Besan\u00e7on , Besan\u00e7on ,","place":["France"]},{"name":"SINERGIES Laboratory, University Marie & Louis Pasteur , Besan\u00e7on ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose","family":"Montero-Cabezas","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Leiden University Medical Center , Leiden ,","place":["The Netherlands"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerry","family":"O\u2019Sullivan","sequence":"additional","affiliation":[{"name":"Interventional Radiology, Galway University Hospital , Galway ,","place":["Ireland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"Pola","sequence":"additional","affiliation":[{"name":"Percorso Trombosi, Dipartimento di Scienze dell\u2019Invercchiamento, Ortopediche e Reumatologiche, Fondazione Policlinico Universitario A. Gemelli IRCCS, Universit\u00e0 Cattolica del Sacro Cuore , Rome ,","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9768-0000","authenticated-orcid":false,"given":"Piotr","family":"Pruszczyk","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and Cardiology with Centre for Thromboembolism, Medical University of Warsaw , Warsaw ,","place":["Poland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1633-8391","authenticated-orcid":false,"given":"Olivier","family":"Sanchez","sequence":"additional","affiliation":[{"name":"Department of Pneumology and Intensive Care Unit, Universit\u00e9 Paris Cit\u00e9, H\u00f4pital Europ\u00e9en Georges Pompidou, AP-HP, Paris ,","place":["France"]},{"name":"INSERM U970 Paris Cardiovascular Research Center , Paris ,","place":["France"]},{"name":"F-CRIN INNOVTE Network , Saint-Etienne ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6934-5355","authenticated-orcid":false,"given":"Oliver","family":"Schlager","sequence":"additional","affiliation":[{"name":"Division of Angiology, Department of Medicine II, Medical University of Vienna , Vienna ,","place":["Austria"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacob","family":"Schultz","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Aarhus Univeristy Hospital , Aarhus ,","place":["Denmark"]},{"name":"Department of Clinical Medicine, Aarhus University , Aarhus ,","place":["Denmark"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Umit Yasar","family":"Sinan","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Istanbul University-Cerrahpasa Cardiology Institute , Istanbul ,","place":["T\u00fcrkiye"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Cristina","family":"Vedovati","sequence":"additional","affiliation":[{"name":"Internal, Vascular and Emergency Medicine, Department of Medicine and Surgery, University of Perugia , Perugia ,","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8698-2858","authenticated-orcid":false,"given":"Peter","family":"Verhamme","sequence":"additional","affiliation":[{"name":"Vascular Medicine and Haemostasis, Department of Cardiovascular Diseases, University Hospitals Leuven , Leuven ,","place":["Belgium"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed","family":"Zaher","sequence":"additional","affiliation":[{"name":"Senior Clinical Fellow in Critical Care, Oxford University Hospitals NHS Foundation Trust, Oxford ,","place":["United Kingdom"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Menno V","family":"Huisman","sequence":"additional","affiliation":[{"name":"Department of Medicine\u2014Thrombosis and Hemostasis, Leiden University Medical Center , Albinusdreef 2, 2300 RC, Leiden ,","place":["the Netherlands"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stavros V","family":"Konstantinides","sequence":"additional","affiliation":[{"name":"Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg University , Langenbeckstra\u00dfe 1 55131 Mainz ,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,10,29]]},"reference":[{"key":"2026031607515015400_zuaf141-B1","doi-asserted-by":"crossref","first-page":"31","DOI":"10.3810\/hp.2014.02.1089","article-title":"The Massachusetts General Hospital Pulmonary Embolism Response Team (MGH PERT): creation of a multidisciplinary program to improve care of patients with massive and submassive pulmonary embolism","volume":"42","author":"Provias","year":"2014","journal-title":"Hosp Pract"},{"key":"2026031607515015400_zuaf141-B2","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1161\/CIRCULATIONAHA.115.015086","article-title":"Multidisciplinary pulmonary embolism response teams","volume":"133","author":"Dudzinski","year":"2016","journal-title":"Circulation"},{"key":"2026031607515015400_zuaf141-B3","doi-asserted-by":"crossref","first-page":"1738","DOI":"10.1378\/chest.13-1562","article-title":"A multidisciplinary pulmonary embolism response team","volume":"144","author":"Kabrhel","year":"2013","journal-title":"Chest"},{"key":"2026031607515015400_zuaf141-B4","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1080\/21548331.2017.1309954","article-title":"Nuts and bolts of running a pulmonary embolism response team: results from an organizational survey of the national PERT consortium members","volume":"45","author":"Barnes","year":"2017","journal-title":"Hosp Pract"},{"key":"2026031607515015400_zuaf141-B5","first-page":"463","article-title":"Acute and long-term outcomes of patients with high-risk pulmonary embolism treated with advanced therapies","volume":"14","author":"Verstraete","year":"2025","journal-title":"Eur Heart J Acute Cardiovasc Care"},{"key":"2026031607515015400_zuaf141-B6","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/S2213-2600(19)30354-6","article-title":"Trends in mortality related to pulmonary embolism in the European region, 2000\u201315: analysis of vital registration data from the WHO Mortality Database","volume":"8","author":"Barco","year":"2020","journal-title":"Lancet Respir Med"},{"key":"2026031607515015400_zuaf141-B7","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S2213-2600(20)30417-3","article-title":"Age-sex specific pulmonary embolism-related mortality in the USA and Canada, 2000\u201318: an analysis of the WHO mortality database and of the CDC multiple cause of death database","volume":"9","author":"Barco","year":"2021","journal-title":"Lancet Respir Med"},{"key":"2026031607515015400_zuaf141-B8","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.jacc.2023.10.026","article-title":"Contemporary management and outcomes of patients with high-risk pulmonary embolism","volume":"83","author":"Kobayashi","year":"2024","journal-title":"J Am Coll Cardiol"},{"key":"2026031607515015400_zuaf141-B9","doi-asserted-by":"crossref","first-page":"e623","DOI":"10.4244\/EIJ-D-22-00246","article-title":"Percutaneous treatment options for acute pulmonary embolism: a clinical consensus statement by the ESC working group on pulmonary circulation and right ventricular function and the European association of percutaneous cardiovascular interventions","volume":"18","author":"Pruszczyk","year":"2022","journal-title":"EuroIntervention"},{"key":"2026031607515015400_zuaf141-B10","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1038\/s41569-023-00876-0","article-title":"Interventional therapies for pulmonary embolism","volume":"20","author":"Gotzinger","year":"2023","journal-title":"Nat Rev Cardiol"},{"key":"2026031607515015400_zuaf141-B11","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1161\/CIRCULATIONAHA.124.067482","article-title":"Pulmonary embolism research collaborative A. Standardized data elements for patients with acute pulmonary embolism: a consensus report from the pulmonary embolism research collaborative","volume":"150","author":"Rosenfield","year":"2024","journal-title":"Circulation"},{"key":"2026031607515015400_zuaf141-B12","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1093\/eurheartj\/ehz405","article-title":"2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS)","volume":"41","author":"Konstantinides","year":"2020","journal-title":"Eur Heart J"},{"key":"2026031607515015400_zuaf141-B13","doi-asserted-by":"crossref","first-page":"18028","DOI":"10.1038\/nrdp.2018.28","article-title":"Pulmonary embolism","volume":"4","author":"Huisman","year":"2018","journal-title":"Nat Rev Dis Primers"},{"key":"2026031607515015400_zuaf141-B14","doi-asserted-by":"crossref","first-page":"2463","DOI":"10.1097\/01.CCM.0000235743.38172.6E","article-title":"Findings of the first consensus conference on medical emergency teams","volume":"34","author":"Devita","year":"2006","journal-title":"Crit Care Med"},{"key":"2026031607515015400_zuaf141-B15","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.1016\/j.jacc.2018.12.084","article-title":"Standardized team-based care for cardiogenic shock","volume":"73","author":"Tehrani","year":"2019","journal-title":"J Am Coll Cardiol"},{"key":"2026031607515015400_zuaf141-B16","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1161\/CIRCULATIONAHA.119.040654","article-title":"Shock team approach in refractory cardiogenic shock requiring short-term mechanical circulatory support: a proof of concept","volume":"140","author":"Taleb","year":"2019","journal-title":"Circulation"},{"key":"2026031607515015400_zuaf141-B17","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1016\/j.jacc.2021.07.044","article-title":"Critical care cardiology trials network I. Management and outcomes of cardiogenic shock in cardiac ICUs with versus without shock teams","volume":"78","author":"Papolos","year":"2021","journal-title":"J Am Coll Cardiol"},{"key":"2026031607515015400_zuaf141-B18","doi-asserted-by":"crossref","first-page":"3146","DOI":"10.1093\/eurheartj\/ehab373","article-title":"Triaging acute pulmonary embolism for home treatment by Hestia or simplified PESI criteria: the HOME-PE randomized trial","volume":"42","author":"Roy","year":"2021","journal-title":"Eur Heart J"},{"key":"2026031607515015400_zuaf141-B19","first-page":"2933","article-title":"Safety of treating acute pulmonary embolism at home: an individual patient data meta-analysis","volume":"45","author":"Luijten","year":"2024","journal-title":"Eur Heart J"},{"key":"2026031607515015400_zuaf141-B20","doi-asserted-by":"crossref","first-page":"e774","DOI":"10.1161\/CIR.0000000000000707","article-title":"Interventional therapies for acute pulmonary embolism: current Status and principles for the development of novel evidence: a scientific statement from the American Heart Association","volume":"140","author":"Giri","year":"2019","journal-title":"Circulation"},{"key":"2026031607515015400_zuaf141-B21","doi-asserted-by":"crossref","first-page":"7755","DOI":"10.3390\/jcm12247755","article-title":"Mechanical support strategies for high-risk procedures in the invasive cardiac catheterization laboratory: a state-of-the-art review","volume":"12","author":"Groeneveld","year":"2023","journal-title":"J Clin Med"},{"key":"2026031607515015400_zuaf141-B22","doi-asserted-by":"crossref","first-page":"iv47","DOI":"10.1093\/eurheartjsupp\/suaf001","article-title":"Mechanical circulatory support in acute pulmonary embolism","volume":"27","author":"Mentzel","year":"2025","journal-title":"Eur Heart J Suppl"},{"key":"2026031607515015400_zuaf141-B23","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1016\/j.amjmed.2021.01.026","article-title":"Nineteen-year trends in mortality of patients hospitalized in the United States with high-risk pulmonary embolism","volume":"134","author":"Stein","year":"2021","journal-title":"Am J Med"},{"key":"2026031607515015400_zuaf141-B24","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1093\/eurheartj\/ehz236","article-title":"Trends in thrombolytic treatment and outcomes of acute pulmonary embolism in Germany","volume":"41","author":"Keller","year":"2020","journal-title":"Eur Heart J"},{"key":"2026031607515015400_zuaf141-B25","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1182\/hematology.2020000167","article-title":"Advanced therapies and extracorporeal membrane oxygenation for the management of high-risk pulmonary embolism","volume":"2020","author":"Gangaraju","year":"2020","journal-title":"Hematology Am Soc Hematol Educ Program"},{"key":"2026031607515015400_zuaf141-B26","doi-asserted-by":"crossref","first-page":"2704","DOI":"10.3390\/jcm14082704","article-title":"Management of hemodynamic and respiratory instability and anesthetic approaches in patients undergoing pulmonary thrombectomy for pulmonary embolism","volume":"14","author":"Gonzalez-Suarez","year":"2025","journal-title":"J Clin Med"},{"key":"2026031607515015400_zuaf141-B27","doi-asserted-by":"crossref","first-page":"4196","DOI":"10.1093\/eurheartj\/ehy464","article-title":"Outcomes after extracorporeal membrane oxygenation for the treatment of high-risk pulmonary embolism: a multicentre series of 52 cases","volume":"39","author":"Meneveau","year":"2018","journal-title":"Eur Heart J"},{"key":"2026031607515015400_zuaf141-B28","doi-asserted-by":"crossref","first-page":"2102977","DOI":"10.1183\/13993003.02977-2021","article-title":"Optimal reperfusion strategy in acute high-risk pulmonary embolism requiring extracorporeal membrane oxygenation support: a systematic review and meta-analysis","volume":"60","author":"Chopard","year":"2022","journal-title":"Eur Respir J"},{"key":"2026031607515015400_zuaf141-B29","first-page":"232","article-title":"Percutaneous large-bore aspiration embolectomy with veno-arterial extracorporal membrane oxygenation support or standby in patients with high-risk pulmonary embolism and contraindications to thrombolysis: a preliminary single centre experience","volume":"12","author":"Kucher","year":"2023","journal-title":"Eur Heart J Acute Cardiovasc Care"},{"key":"2026031607515015400_zuaf141-B30","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1182\/blood.2019001605","article-title":"How I assess and manage the risk of bleeding in patients treated for venous thromboembolism","volume":"135","author":"Klok","year":"2020","journal-title":"Blood"},{"key":"2026031607515015400_zuaf141-B31","doi-asserted-by":"crossref","first-page":"2002828","DOI":"10.1183\/13993003.02828-2020","article-title":"ERS statement on chronic thromboembolic pulmonary hypertension","volume":"57","author":"Delcroix","year":"2021","journal-title":"Eur Respir J"},{"key":"2026031607515015400_zuaf141-B32","doi-asserted-by":"crossref","first-page":"3618","DOI":"10.1093\/eurheartj\/ehac237","article-title":"2022 ESC\/ERS guidelines for the diagnosis and treatment of pulmonary hypertension","volume":"43","author":"Humbert","year":"2022","journal-title":"Eur Heart J"},{"key":"2026031607515015400_zuaf141-B33","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1093\/ehjci\/jeaf050","article-title":"Optimal approach to performing and reporting computed tomography angiography for suspected acute pulmonary embolism: a clinical consensus statement of the ESC Working Group on Pulmonary Circulation & Right Ventricular Function, the Fleischner Society, the Association for Acute CardioVascular Care (ACVC) and the European Association of Cardiovascular Imaging (EACVI) of the ESC, endorsed by European Respiratory Society (ERS), Asian Society of Thoracic Radiology (ASTR), European Society of Thoracic Imaging (ESTI), and Society of Thoracic Radiology (STR)","volume":"26","author":"Klok","year":"2025","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"2026031607515015400_zuaf141-B34","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/j.healun.2019.03.003","article-title":"Usefulness of standard computed tomography pulmonary angiography performed for acute pulmonary embolism for identification of chronic thromboembolic pulmonary hypertension: results of the InShape III study","volume":"38","author":"Ende-Verhaar","year":"2019","journal-title":"J Heart Lung Transplant"},{"key":"2026031607515015400_zuaf141-B35","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1016\/j.chest.2022.11.045","article-title":"Preexisting chronic thromboembolic pulmonary hypertension in acute pulmonary embolism","volume":"163","author":"Barco","year":"2023","journal-title":"Chest"},{"key":"2026031607515015400_zuaf141-B36","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1016\/S0140-6736(02)07920-5","article-title":"Bioavailability of subcutaneous low-molecular-weight heparin to patients on vasopressors","volume":"359","author":"Dorffler-Melly","year":"2002","journal-title":"Lancet"},{"key":"2026031607515015400_zuaf141-B37","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.ahj.2022.05.011","article-title":"Ultrasound-facilitated, catheter-directed thrombolysis vs anticoagulation alone for acute intermediate-high-risk pulmonary embolism: rationale and design of the HI-PEITHO study","volume":"251","author":"Klok","year":"2022","journal-title":"Am Heart J"},{"key":"2026031607515015400_zuaf141-B38","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1002\/phar.2868","article-title":"Approaches to precision-based anticoagulation management in the critically ill","volume":"43","author":"Dager","year":"2023","journal-title":"Pharmacotherapy"},{"key":"2026031607515015400_zuaf141-B39","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1186\/s13613-024-01315-0","article-title":"Frailty assessment in critically ill older adults: a narrative review","volume":"14","author":"Moisi","year":"2024","journal-title":"Ann Intensive Care"},{"key":"2026031607515015400_zuaf141-B40","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/j.jtha.2024.10.015","article-title":"Risk assessment and management strategies in older patients with acute pulmonary embolism","volume":"23","author":"Luijten","year":"2025","journal-title":"J Thromb Haemost"},{"key":"2026031607515015400_zuaf141-B41","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1186\/s13613-018-0458-7","article-title":"Caring for the critically ill patients over 80: a narrative review","volume":"8","author":"Guidet","year":"2018","journal-title":"Ann Intensive Care"},{"key":"2026031607515015400_zuaf141-B42","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2024-324691","article-title":"Effective risk stratification in pulmonary embolism: evaluating current tools and identifying research gaps","author":"Stenger","journal-title":"Heart"},{"key":"2026031607515015400_zuaf141-B43","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1007\/s00392-022-02077-0","article-title":"Pulmonary embolism response team (PERT) implementation and its clinical value across countries: a scoping review and meta-analysis","volume":"112","author":"Hobohm","year":"2023","journal-title":"Clin Res Cardiol"},{"key":"2026031607515015400_zuaf141-B44","doi-asserted-by":"crossref","first-page":"623","DOI":"10.5603\/CJ.2019.0127","article-title":"Expert opinion on the creating and operating of the regional pulmonary embolism response teams (PERT). Polish PERT Initiative","volume":"26","author":"Araszkiewicz","year":"2019","journal-title":"Cardiol J"},{"key":"2026031607515015400_zuaf141-B45","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/j.chest.2016.03.011","article-title":"A multidisciplinary pulmonary embolism response team: initial 30-month experience with a novel approach to delivery of care to patients with submassive and massive pulmonary embolism","volume":"150","author":"Kabrhel","year":"2016","journal-title":"Chest"},{"key":"2026031607515015400_zuaf141-B46","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/j.jvsv.2018.11.014","article-title":"The implementation of a pulmonary embolism response team in the management of intermediate- or high-risk pulmonary embolism","volume":"7","author":"Xenos","year":"2019","journal-title":"J Vasc Surg Venous Lymphat Disord"},{"key":"2026031607515015400_zuaf141-B47","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1016\/j.amjcard.2019.07.043","article-title":"Impact of multidisciplinary pulmonary embolism response team availability on management and outcomes","volume":"124","author":"Chaudhury","year":"2019","journal-title":"Am J Cardiol"},{"key":"2026031607515015400_zuaf141-B48","doi-asserted-by":"crossref","first-page":"1076029620928420","DOI":"10.1177\/1076029620928420","article-title":"Effects of a consensus-based pulmonary embolism treatment algorithm and response team on treatment modality choices, outcomes, and complications","volume":"26","author":"Melamed","year":"2020","journal-title":"Clin Appl Thromb Hemost"},{"key":"2026031607515015400_zuaf141-B49","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1186\/s12931-020-01422-z","article-title":"Adoption of a dedicated multidisciplinary team is associated with improved survival in acute pulmonary embolism","volume":"21","author":"Myc","year":"2020","journal-title":"Respir Res"},{"key":"2026031607515015400_zuaf141-B50","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1016\/j.amjmed.2020.03.058","article-title":"Changes in care for acute pulmonary embolism through A multidisciplinary pulmonary embolism response team","volume":"133","author":"Carroll","year":"2020","journal-title":"Am J Med"},{"key":"2026031607515015400_zuaf141-B51","doi-asserted-by":"crossref","first-page":"889","DOI":"10.3390\/diagnostics15070889","article-title":"Role of artificial intelligence in the diagnosis and management of pulmonary embolism: a comprehensive review","volume":"15","author":"Naser","year":"2025","journal-title":"Diagnostics"},{"key":"2026031607515015400_zuaf141-B52","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.mayocpiqo.2023.03.001","article-title":"Evaluating the performance of a commercially available artificial intelligence algorithm for automated detection of pulmonary embolism on contrast-enhanced computed tomography and computed tomography pulmonary angiography in patients with coronavirus disease 2019","volume":"7","author":"Zaazoue","year":"2023","journal-title":"Mayo Clin Proc Innov Qual Outcomes"}],"container-title":["European Heart Journal: Acute Cardiovascular Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ehjacc\/advance-article-pdf\/doi\/10.1093\/ehjacc\/zuaf141\/65023080\/zuaf141.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ehjacc\/article-pdf\/15\/2\/151\/65023080\/zuaf141.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ehjacc\/article-pdf\/15\/2\/151\/65023080\/zuaf141.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T11:52:08Z","timestamp":1773661928000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ehjacc\/article\/15\/2\/151\/8305660"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,29]]},"references-count":52,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2025,10,29]]},"published-print":{"date-parts":[[2026,3,16]]}},"URL":"https:\/\/doi.org\/10.1093\/ehjacc\/zuaf141","relation":{},"ISSN":["2048-8726","2048-8734"],"issn-type":[{"value":"2048-8726","type":"print"},{"value":"2048-8734","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,2]]},"published":{"date-parts":[[2025,10,29]]}}}