{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T06:57:09Z","timestamp":1789541829607,"version":"build-2803163510"},"reference-count":27,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T00:00:00Z","timestamp":1774051200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,5,19]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>The prognosis of right heart failure (RHF) is purported to be poor, yet there are limited data detailing the implications of concomitant cardiogenic shock (CS) and RHF. We sought to characterize the prevalence and impact of RHF on patients with CS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>We queried the Vizient\u00ae Clinical Database to identify adults \u226518 years old admitted 1 October 2015 to 30 June 2023, with a diagnosis of CS. Using inverse probability of treatment weighting (IPTW), adjusting for demographics, comorbidities, and markers of acuity, we compared in-hospital mortality between patients with and without a diagnosis of RHF as well as by Society of Cardiovascular Angiography and Interventions (SCAI) shock stages B through E. We identified 348 919 patients with CS, including 11.3% (n = 39 610) with RHF. Patients with RHF were younger (60.5 vs. 65.5; P &amp;lt; 0.001), more frequently had heart failure (HF) as their primary admission diagnosis (40.8% vs. 23.2%; P &amp;lt; 0.001), and presented in earlier SCAI shock stages. Patients with non-RHF CS were more likely to have acute myocardial infarction (AMI) as primary admission diagnosis (20.7% vs. 8.2%; P &amp;lt; 0.001) and present with out-of-hospital cardiac arrest (11.5% vs. 5.8%; P &amp;lt; 0.001). After adjustment, RHF was associated with a 2.4% [95% confidence interval (CI): 1.9\u20132.9%; P &amp;lt; 0.001] increase in absolute mortality and when stratified by SCAI shock stage. Patients with isolated RHF were found to have a higher absolute in-hospital mortality [9.8%; 95% (CI): 8.6\u201311.0%; P &amp;lt; 0.001].<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The presence of RHF is associated with increased in-hospital mortality in patients admitted with CS.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ehjacc\/zuag041","type":"journal-article","created":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T12:41:42Z","timestamp":1774010502000},"page":"415-423","source":"Crossref","is-referenced-by-count":2,"title":["Impact of right heart failure in patients with cardiogenic shock"],"prefix":"10.1093","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3911-2806","authenticated-orcid":false,"given":"Roberto","family":"Lapetina Arroyo","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Yale School of Medicine , New Haven, CT ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pavan","family":"Khosla","sequence":"additional","affiliation":[{"name":"Yale School of Medicine , New Haven, CT ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9sar","family":"Caraballo","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Yale School of Medicine , New Haven, CT ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose Victor","family":"Jimenez","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Yale School of Medicine , New Haven, CT ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Schwann","sequence":"additional","affiliation":[{"name":"Section of Cardiovascular Medicine, Yale School of Medicine , New Haven, CT, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann","family":"Gage","sequence":"additional","affiliation":[{"name":"Centennial Medical Center Department of Cardiovascular Medicine, , Nashville, TN ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3762-7918","authenticated-orcid":false,"given":"Samuel B","family":"Brusca","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology, University of California SanFrancisco , San Francisco, CA ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Barnett","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology, University of California SanFrancisco , San Francisco, CA ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Jacobs","sequence":"additional","affiliation":[{"name":"Section of Cardiovascular Medicine, Yale School of Medicine , New Haven, CT, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tariq","family":"Ali","sequence":"additional","affiliation":[{"name":"Section of Cardiovascular Medicine, Yale School of Medicine , New Haven, CT, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0595-1492","authenticated-orcid":false,"given":"P Elliott","family":"Miller","sequence":"additional","affiliation":[{"name":"Section of Cardiovascular Medicine, Yale School of Medicine , New Haven, CT, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,3,21]]},"reference":[{"key":"2026051912353970800_zuag041-B1","doi-asserted-by":"crossref","first-page":"e15","DOI":"10.1164\/rccm.201806-1160ST","article-title":"Assessment of right ventricular function in the research setting: knowledge gaps and pathways forward. An official American Thoracic Society Research statement","volume":"198","author":"Lahm","year":"2018","journal-title":"Am J Respir Crit Care Med"},{"key":"2026051912353970800_zuag041-B2","doi-asserted-by":"crossref","first-page":"e578","DOI":"10.1161\/CIR.0000000000000560","article-title":"Evaluation and management of right-sided heart failure: a scientific statement from the American Heart Association","volume":"137","author":"Konstam","year":"2018","journal-title":"Circulation"},{"key":"2026051912353970800_zuag041-B3","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1002\/ejhf.478","article-title":"Contemporary management of acute right ventricular failure: a statement from the Heart Failure Association and the Working Group on Pulmonary Circulation and Right Ventricular Function of the European Society of Cardiology","volume":"18","author":"Harjola","year":"2016","journal-title":"Eur J Heart 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