{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:46:53Z","timestamp":1790642813108,"version":"4.1.0"},"reference-count":38,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2020,8,5]],"date-time":"2020-08-05T00:00:00Z","timestamp":1596585600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,7,20]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims\u2003<\/jats:title>\n                  <jats:p>There are only very few data on the prognostic value of stress cardiovascular magnetic resonance (CMR) in elderly people, while life expectancy of the general population is steadily increasing. Therefore, this study aims to assess the prognostic value of vasodilator stress perfusion CMR in elderly &amp;gt;75\u2009years.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results\u2003<\/jats:title>\n                  <jats:p>Between 2008 and 2017, we included consecutive elderly &amp;gt;75\u2009years without known coronary artery disease (CAD) referred for dipyridamole stress CMR. They were followed for the occurrence of major adverse cardiovascular events (MACE) including cardiac death or non-fatal myocardial infarction. Univariate and multivariate analyses were performed to determine the prognostic value of ischaemia or late gadolinium enhancement. Of 754 elderly individuals (82.0\u2009\u00b1\u20093.9\u2009years, 48.4% men), 659 (87.4%) completed the follow-up with median follow-up of 4.7\u2009years. Using Kaplan\u2013Meier analysis, the presence of myocardial ischaemia was associated with the occurrence of MACE [hazard ratio (HR) 5.38, 95% confidence interval (CI): 3.56\u20139.56; P\u2009&amp;lt;\u20090.001]. In a multivariable Cox regression including clinical characteristics and CMR indexes, inducible ischaemia was an independent predictor of a higher incidence of MACE (HR 4.44, 95% CI: 2.51\u20137.86; P\u2009&amp;lt;\u20090.001). In patients without ischaemia, the occurrence of MACE was lower in women when compared with men (P\u2009&amp;lt;\u20090.01).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion\u2003<\/jats:title>\n                  <jats:p>Stress CMR is safe and has discriminative prognostic value in elderly, with a significantly lower event rate of future cardiovascular event or death in subjects without ischaemia or infarction.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjci\/jeaa193","type":"journal-article","created":{"date-parts":[[2020,6,14]],"date-time":"2020-06-14T11:07:07Z","timestamp":1592132827000},"page":"904-911","source":"Crossref","is-referenced-by-count":22,"title":["Prognostic value of dipyridamole stress perfusion cardiovascular magnetic resonance in elderly patients &amp;gt;75 years with suspected coronary artery disease"],"prefix":"10.1093","volume":"22","author":[{"given":"Th\u00e9o","family":"Pezel","sequence":"first","affiliation":[{"name":"Department of Cardiology Cardiovascular Magnetic Resonance Laboratory, The Institut Cardiovasculaire Paris Sud, H\u00f4pital Priv\u00e9 Jacques CARTIER, Ramsay Sant\u00e9, 91300 Massy, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Sanguineti","sequence":"additional","affiliation":[{"name":"Department of Cardiology Cardiovascular Magnetic Resonance Laboratory, The Institut Cardiovasculaire Paris Sud, H\u00f4pital Priv\u00e9 Jacques CARTIER, Ramsay Sant\u00e9, 91300 Massy, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marine","family":"Kinnel","sequence":"additional","affiliation":[{"name":"Department of Cardiology Cardiovascular Magnetic Resonance Laboratory, The Institut Cardiovasculaire Paris Sud, H\u00f4pital Priv\u00e9 Jacques CARTIER, Ramsay Sant\u00e9, 91300 Massy, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Hovasse","sequence":"additional","affiliation":[{"name":"Department of Cardiology Cardiovascular Magnetic Resonance Laboratory, The Institut Cardiovasculaire Paris Sud, H\u00f4pital Priv\u00e9 Jacques CARTIER, Ramsay Sant\u00e9, 91300 Massy, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Garot","sequence":"additional","affiliation":[{"name":"Department of Cardiology Cardiovascular Magnetic Resonance Laboratory, The Institut Cardiovasculaire Paris Sud, H\u00f4pital Priv\u00e9 Jacques CARTIER, Ramsay Sant\u00e9, 91300 Massy, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thierry","family":"Unterseeh","sequence":"additional","affiliation":[{"name":"Department of Cardiology Cardiovascular Magnetic Resonance Laboratory, The Institut Cardiovasculaire Paris Sud, H\u00f4pital Priv\u00e9 Jacques CARTIER, Ramsay Sant\u00e9, 91300 Massy, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00e9phane","family":"Champagne","sequence":"additional","affiliation":[{"name":"Department of Cardiology Cardiovascular Magnetic Resonance Laboratory, The Institut Cardiovasculaire Paris Sud, H\u00f4pital Priv\u00e9 Jacques CARTIER, Ramsay Sant\u00e9, 91300 Massy, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yves","family":"Louvard","sequence":"additional","affiliation":[{"name":"Department of Cardiology Cardiovascular Magnetic Resonance Laboratory, The Institut Cardiovasculaire Paris Sud, H\u00f4pital Priv\u00e9 Jacques CARTIER, Ramsay Sant\u00e9, 91300 Massy, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie Claude","family":"Morice","sequence":"additional","affiliation":[{"name":"Department of Cardiology Cardiovascular Magnetic Resonance Laboratory, The Institut Cardiovasculaire Paris Sud, H\u00f4pital Priv\u00e9 Jacques CARTIER, Ramsay Sant\u00e9, 91300 Massy, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00e9r\u00f4me","family":"Garot","sequence":"additional","affiliation":[{"name":"Department of Cardiology Cardiovascular Magnetic Resonance Laboratory, The Institut Cardiovasculaire Paris Sud, H\u00f4pital Priv\u00e9 Jacques CARTIER, Ramsay Sant\u00e9, 91300 Massy, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,8,5]]},"reference":[{"key":"2021072018500475900_jeaa193-B1","doi-asserted-by":"crossref","first-page":"2264","DOI":"10.1016\/j.jacc.2007.08.002","article-title":"2007 chronic angina focused update of the ACC\/AHA 2002 guidelines for the management of patients with chronic stable angina: a report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines Writing Group to develop the focused update of the 2002 guidelines for the management of patients with chronic stable 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