{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T23:47:38Z","timestamp":1793836058828,"version":"4.6.1"},"reference-count":28,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2020,8,12]],"date-time":"2020-08-12T00:00:00Z","timestamp":1597190400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100001316","name":"Abbott Laboratories","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001316","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Fundaci\u00f3n University of Alcal\u00e1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,1,22]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>To evaluate the burden of tricuspid regurgitation (TR) in a large cohort, determine the right ventricle involvement of patients with TR and determine the characteristics of isolated TR.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>Prospective study where consecutive patients undergoing an echocardiographic study in 10 centres were included. All studies with significant TR (at least moderate) were selected. We considered that patients with one of pulmonary systolic hypertension &amp;gt;50\u2009mmHg, left ventricular ejection fraction &amp;lt;35%, New York Heart Association III\u2013IV, or older than 85\u2009years, had a high surgical risk. A total of 35\u00a0088 echocardiograms were performed. Significant TR was detected in 6% of studies. Moderate TR was found in 69.6%, severe in 25.5%, massive in 3.9%, and torrential in 1.0% of patients. Right ventricle was dilated in 81.7% of patients with massive\/torrential TR, in 55.9% with severe TR, and in 29.3% with moderate TR (P\u2009&amp;lt;\u20090.001). Primary TR was present in 7.4% of patients whereas secondary TR was present in 92.6%. Mitral or aortic valve disease was the most common aetiology (54.6%), following by isolated TR (16%). Up to 51.9% of patients with severe, massive, or torrential primary TR and 57% of patients with severe, massive, or torrential secondary TR had a high surgical risk.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Significant TR is a prevalent condition and a high proportion of these patients have an indication for valve intervention. More than a half of patients with severe, massive, or torrential TR had a high surgical risk. Massive\/torrential TR may have implications regarding selection and monitoring patients for percutaneous treatment.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjci\/jeaa205","type":"journal-article","created":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T19:09:31Z","timestamp":1593630571000},"page":"196-202","source":"Crossref","is-referenced-by-count":104,"title":["New insights of tricuspid regurgitation: a large-scale prospective cohort study"],"prefix":"10.1093","volume":"22","author":[{"given":"Jos\u00e9 Mar\u00eda","family":"Vieitez","sequence":"first","affiliation":[{"name":"Department of Cardiology, CIBERCV University Hospital Ramon y Cajal, Carretera de Colmenar Km 9.100, Madrid 28034, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Manuel","family":"Monteagudo","sequence":"additional","affiliation":[{"name":"Department of Cardiology, CIBERCV University Hospital Ramon y Cajal, Carretera de Colmenar Km 9.100, Madrid 28034, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Mahia","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Hospital Clinic San Carlos, calle Prof Mart\u00edn Lagos, Madrid 28040, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leopoldo","family":"Perez","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Hospital Clinic San Carlos, calle Prof Mart\u00edn Lagos, Madrid 28040, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa","family":"Lopez","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Hospital La Paz, Paseo de la Castellana, 261, Madrid 28046, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irene","family":"Marco","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Hospital La Paz, Paseo de la Castellana, 261, Madrid 28046, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Perone","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Hospital La Paz, Paseo de la Castellana, 261, Madrid 28046, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa","family":"Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Hospital Vall d`Hebron, Passeig de la Vall d'Hebron, 119, 129, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Sitges","sequence":"additional","affiliation":[{"name":"Barcelona Hospital Clinic de Barcelona, Carrer de Villarroel 170, Barcelona 08036, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Bouzas","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Hospital Complex A Coru\u00f1a, As Xubias 84, A Coru\u00f1a 15006, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Violeta","family":"Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Hospital Cl\u00ednico Universitario de Santiago de Compostela, IDIS (CIBERCV)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Hospital of Santa Creu I Sant Pau, Carrer de Sant Quint\u00ed, 89, Barcelona 08041, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Alonso","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Hospital of Leon, Altos de Nava, Le\u00f3n 24008, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Carrasco","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Hospital Virgen de la Victoria, Campus de Teatinos, M\u00e1laga 29010, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Adeba","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Hospital Central de Asturias, Avenida de Roma s\/n, Oviedo 33011, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Mar\u00eda","family":"de la Heras","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Hospital Central de Asturias, Avenida de Roma s\/n, Oviedo 33011, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Covadonga","family":"Fernandez-Golfin","sequence":"additional","affiliation":[{"name":"Department of Cardiology, CIBERCV University Hospital Ramon y Cajal, Carretera de Colmenar Km 9.100, Madrid 28034, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Luis","family":"Zamorano","sequence":"additional","affiliation":[{"name":"Department of Cardiology, CIBERCV University Hospital Ramon y Cajal, Carretera de Colmenar Km 9.100, Madrid 28034, Spain"},{"name":"Department of Cardiology, La Zarzuela Hospital, Calle de Pleyades, 25, Madrid 28023, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,8,12]]},"reference":[{"key":"2021031107200132100_jeaa205-B1","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/j.jcmg.2018.06.014","article-title":"Burden of tricuspid regurgitation in patients diagnosed in the community setting","volume":"12","author":"Topilsky","year":"2019","journal-title":"JACC Cardiovasc Imaging"},{"key":"2021031107200132100_jeaa205-B2","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.jacc.2003.09.036","article-title":"Impact of tricuspid regurgitation on long-term survival","volume":"43","author":"Nath","year":"2004","journal-title":"J Am Coll 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Part 2: mitral and tricuspid regurgitation (native valve disease)","volume":"11","author":"Lancellotti","year":"2010","journal-title":"Eur J Echocardiogr"},{"key":"2021031107200132100_jeaa205-B10","doi-asserted-by":"crossref","first-page":"1342","DOI":"10.1093\/ehjci\/jex139","article-title":"The need for a new tricuspid regurgitation grading scheme","volume":"18","author":"Hahn","year":"2017","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"2021031107200132100_jeaa205-B11","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1093\/eurheartj\/ehv317","article-title":"2015 ESC\/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: the joint task force for the diagnosis and treatment of pulmonary hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS): Endorsed By: Association for European Paediatric and Congenital Cardiology (AEPC), International Society for Heart and Lung Transplantation 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