{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T23:08:53Z","timestamp":1782169733355,"version":"3.54.5"},"reference-count":28,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2020,9,30]],"date-time":"2020-09-30T00:00:00Z","timestamp":1601424000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>The objective was to compare the incidence and impact on outcomes of measured (PPMM) vs. predicted (PPMP) prosthesis\u2013patient mismatch following transcatheter aortic valve replacement (TAVR).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>All consecutives patients who underwent TAVR between 2007 and 2018 were included. Effective orifice area (EOA) was measured by Doppler-echocardiography using the continuity equation and predicted according to the normal reference for each model and size of valve. PPM was defined using EOA indexed (EOAi) to body surface area as moderate if \u22640.85\u00a0cm2\/m2 and severe if \u2264 0.65\u00a0cm2\/m2 (respectively, \u2264 0.70 and \u2264 0.55\u00a0cm2\/m2 if body mass index\u2009\u2265 30\u00a0kg\/m2). The outcome endpoints were high residual gradient (\u226520\u00a0mmHg) and the composite of cardiovascular mortality and hospital readmission for heart failure at 1\u2009year. Overall, 1088 patients underwent a TAVR (55% male, age 79.1\u2009\u00b1\u20098.4\u2009years, and STS score 6.6\u2009\u00b1\u20094.7%); balloon-expandable device was used in 83%. Incidence of moderate (10% vs. 27%) and severe (1% vs. 17%) PPM was markedly lower when defined by predicted vs. measured EOAi (P\u2009&amp;lt;\u20090.001). Balloon-expandable device implantation (OR: 1.90, P\u2009=\u20090.029) and valve-in-valve procedure (n\u2009=\u2009118; OR: 3.21, P\u2009&amp;lt;\u20090.001) were the main factors associated with PPM occurrence. Compared with measured PPM, predicted PPM showed stronger association with high residual gradient. Severe measured or predicted PPM was not associated with clinical outcomes.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>The utilization of the predicted EOAi reclassifies the majority of patients with PPM to no PPM following TAVR. Compared with measured PPM, predicted PPM had stronger association with haemodynamic outcomes, while both methods were not associated with clinical outcomes.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjci\/jeaa235","type":"journal-article","created":{"date-parts":[[2020,8,4]],"date-time":"2020-08-04T19:20:20Z","timestamp":1596568820000},"page":"11-20","source":"Crossref","is-referenced-by-count":58,"title":["Reclassification of prosthesis\u2013patient mismatch after transcatheter aortic valve replacement using predicted vs. measured indexed effective orifice area"],"prefix":"10.1093","volume":"22","author":[{"given":"Julien","family":"Ternacle","sequence":"first","affiliation":[{"name":"Institut Universitaire de Cardiologie et de Pneumologie de Qu\u00e9bec- Universit\u00e9 Laval\/Qu\u00e9bec Heart and Lung Institute, Laval University, 2725 Chemin Sainte-Foy, Qu\u00e9bec city, Qu\u00e9bec G1V-4G5, Canada"},{"name":"Cardiology Department, Expert Valve Center, Henri Mondor ho spital, 51 avenue du Mar\u00e9chal de Lattre de Tassigny, 94000, Cr\u00e9teil, France"},{"name":"INSERM Unit U955, Team 8, Paris-Est Creteil University, Val-de-Marne, 8 rue du G\u00e9n\u00e9ral Sarrail, 94010, Cr\u00e9teil, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonardo","family":"Guimaraes","sequence":"additional","affiliation":[{"name":"Institut Universitaire de Cardiologie et de Pneumologie de Qu\u00e9bec- Universit\u00e9 Laval\/Qu\u00e9bec Heart and Lung Institute, Laval University, 2725 Chemin Sainte-Foy, Qu\u00e9bec city, Qu\u00e9bec G1V-4G5, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flavien","family":"Vincent","sequence":"additional","affiliation":[{"name":"Institut Universitaire de Cardiologie et de Pneumologie de Qu\u00e9bec- Universit\u00e9 Laval\/Qu\u00e9bec Heart and Lung Institute, Laval University, 2725 Chemin Sainte-Foy, Qu\u00e9bec city, Qu\u00e9bec G1V-4G5, Canada"},{"name":"D\u00e9partement de cardiologie, CHU de Lille, Institut C\u0153ur Poumon, Universit\u00e9 de Lille, INSERM U1011, Institut Pasteur de Lille, EGID, Boulevard du Professeur Jules Leclercq, 59000 Lille,, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy","family":"C\u00f4t\u00e9","sequence":"additional","affiliation":[{"name":"Institut Universitaire de Cardiologie et de Pneumologie de Qu\u00e9bec- Universit\u00e9 Laval\/Qu\u00e9bec Heart and Lung Institute, Laval University, 2725 Chemin Sainte-Foy, Qu\u00e9bec city, Qu\u00e9bec G1V-4G5, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e9lanie","family":"C\u00f4t\u00e9","sequence":"additional","affiliation":[{"name":"Institut Universitaire de Cardiologie et de Pneumologie de Qu\u00e9bec- Universit\u00e9 Laval\/Qu\u00e9bec Heart and Lung Institute, Laval University, 2725 Chemin Sainte-Foy, Qu\u00e9bec city, Qu\u00e9bec G1V-4G5, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique","family":"Lachance","sequence":"additional","affiliation":[{"name":"Institut Universitaire de Cardiologie et de Pneumologie de Qu\u00e9bec- Universit\u00e9 Laval\/Qu\u00e9bec Heart and Lung Institute, Laval University, 2725 Chemin Sainte-Foy, Qu\u00e9bec city, Qu\u00e9bec G1V-4G5, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Annick","family":"Clavel","sequence":"additional","affiliation":[{"name":"Institut Universitaire de Cardiologie et de Pneumologie de Qu\u00e9bec- Universit\u00e9 Laval\/Qu\u00e9bec Heart and Lung Institute, Laval University, 2725 Chemin Sainte-Foy, Qu\u00e9bec city, Qu\u00e9bec G1V-4G5, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amr E","family":"Abbas","sequence":"additional","affiliation":[{"name":"Oakland University William Beaumont School of Medicine, Auburn Hills, 586 Pioneer Dr, Rochester, MI 48309, USA"},{"name":"Beaumont Health, 3601 W 13 Mile Rd, Royal Oak, MI 48073, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3607-279X","authenticated-orcid":false,"given":"Philippe","family":"Pibarot","sequence":"additional","affiliation":[{"name":"Institut Universitaire de Cardiologie et de Pneumologie de Qu\u00e9bec- Universit\u00e9 Laval\/Qu\u00e9bec Heart and Lung Institute, Laval University, 2725 Chemin Sainte-Foy, Qu\u00e9bec city, Qu\u00e9bec G1V-4G5, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josep","family":"Rod\u00e9s-Cabau","sequence":"additional","affiliation":[{"name":"Institut Universitaire de Cardiologie et de Pneumologie de Qu\u00e9bec- Universit\u00e9 Laval\/Qu\u00e9bec Heart and Lung Institute, Laval University, 2725 Chemin Sainte-Foy, Qu\u00e9bec city, Qu\u00e9bec G1V-4G5, 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