{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T19:34:54Z","timestamp":1790710494852,"version":"4.1.0"},"reference-count":26,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2023,2,17]],"date-time":"2023-02-17T00:00:00Z","timestamp":1676592000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,7,24]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>The procedural planning of transcatheter mitral valve replacement (TMVR) requires a specific imaging assessment to establish patient eligibility. Computed tomography (CT) is considered the reference method. In this setting, data regarding the role of transoesophageal echocardiography (TOE) are lacking. We evaluated the feasibility and reliability of a comprehensive 3D-TOE screening in TMVR candidates.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>We performed a retrospective observational study including 72 consecutive patients who underwent a pre-procedural CT and 3D-TOE for TMVR evaluation. The measurements of mitral annulus (MA), length of anterior mitral leaflet (AML), native left ventricular outflow tract (LVOT), and predicted neo-LVOT acquired with CT and 3D-TOE were compared using a novel semi-automated software for post processing analysis (3 mensio Structural Heart 10.1\u20143mSH, Pie Medical Imaging, Bilthoven, Netherlands). The final suitability decision was given by the valve manufacturer based on CT measurements and clinical conditions. Among 72 patients screened, all patients had adequate image quality for 3D-TOE analysis. 3D-TOE and CT measurements for AML length (r = 0.97), MA area (r = 0.90), perimeter (r = 0.68), anteroposterior (r = 0.88), and posteromedial-anterolateral (r = 0.74) diameters were found highly correlated, as well as for native LVOT (r = 0.86) and predicted neo-LVOT areas (r = 0.96) (all P-values &amp;lt;0.0001). An almost perfect agreement between CT and 3DTOE was found in assessing the eligibility for TMVR implantation (Cohen kappa 0.83, P &amp;lt; 0.001).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>3D-TOE appraisements showed good correlations with CT measurements and high accuracy to predict TMVR screening success.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjci\/jead015","type":"journal-article","created":{"date-parts":[[2023,2,17]],"date-time":"2023-02-17T04:29:38Z","timestamp":1676608178000},"page":"1043-1051","source":"Crossref","is-referenced-by-count":8,"title":["Feasibility and reliability of comprehensive three-dimensional transoesophageal echocardiography screening process for transcatheter mitral valve replacement"],"prefix":"10.1093","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6817-2923","authenticated-orcid":false,"given":"Francesco","family":"Piroli","sequence":"first","affiliation":[{"name":"Cardiovascular Imaging Unit, Cardio-Thoracic-Vascular Department, IRCCS San Raffaele Scientific Institute , via Olgettina 60, 20132 Milan , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Boccellino","sequence":"additional","affiliation":[{"name":"Cardiovascular Imaging Unit, Cardio-Thoracic-Vascular Department, IRCCS San Raffaele Scientific Institute , via Olgettina 60, 20132 Milan , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giacomo","family":"Ingallina","sequence":"additional","affiliation":[{"name":"Cardiovascular Imaging Unit, Cardio-Thoracic-Vascular Department, IRCCS San Raffaele Scientific Institute , via Olgettina 60, 20132 Milan , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Rolando","sequence":"additional","affiliation":[{"name":"Cardiovascular Imaging Unit, Cardio-Thoracic-Vascular Department, IRCCS San Raffaele Scientific Institute , via Olgettina 60, 20132 Milan , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2159-1359","authenticated-orcid":false,"given":"Francesco","family":"Melillo","sequence":"additional","affiliation":[{"name":"Cardiovascular Imaging Unit, Cardio-Thoracic-Vascular Department, IRCCS San Raffaele Scientific Institute , via Olgettina 60, 20132 Milan , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7972-0689","authenticated-orcid":false,"given":"Francesco","family":"Ancona","sequence":"additional","affiliation":[{"name":"Cardiovascular Imaging Unit, Cardio-Thoracic-Vascular Department, IRCCS San Raffaele Scientific Institute , via Olgettina 60, 20132 Milan , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Stella","sequence":"additional","affiliation":[{"name":"Cardiovascular Imaging Unit, Cardio-Thoracic-Vascular Department, IRCCS San Raffaele Scientific Institute , via Olgettina 60, 20132 Milan , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federico","family":"Biondi","sequence":"additional","affiliation":[{"name":"Cardiovascular Imaging Unit, Cardio-Thoracic-Vascular Department, IRCCS San Raffaele Scientific Institute , via Olgettina 60, 20132 Milan , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1564-2060","authenticated-orcid":false,"given":"Anna","family":"Palmisano","sequence":"additional","affiliation":[{"name":"Cardiovascular Imaging Unit, Cardio-Thoracic-Vascular Department, IRCCS San Raffaele Scientific Institute , via Olgettina 60, 20132 Milan , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Esposito","sequence":"additional","affiliation":[{"name":"Cardiovascular Imaging Unit, Cardio-Thoracic-Vascular Department, IRCCS San Raffaele Scientific Institute , via Olgettina 60, 20132 Milan , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3075-0203","authenticated-orcid":false,"given":"Paolo","family":"Denti","sequence":"additional","affiliation":[{"name":"Cardiovascular Imaging Unit, Cardio-Thoracic-Vascular Department, IRCCS San Raffaele Scientific Institute , via Olgettina 60, 20132 Milan , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9732-9459","authenticated-orcid":false,"given":"Matteo","family":"Montorfano","sequence":"additional","affiliation":[{"name":"Cardiovascular Imaging Unit, Cardio-Thoracic-Vascular Department, IRCCS San Raffaele Scientific Institute , via Olgettina 60, 20132 Milan , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3691-1709","authenticated-orcid":false,"given":"Francesco","family":"Maisano","sequence":"additional","affiliation":[{"name":"Cardiovascular Imaging Unit, Cardio-Thoracic-Vascular Department, IRCCS San Raffaele Scientific Institute , via Olgettina 60, 20132 Milan , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Castiglioni","sequence":"additional","affiliation":[{"name":"Cardiovascular Imaging Unit, Cardio-Thoracic-Vascular Department, IRCCS San Raffaele Scientific Institute , via Olgettina 60, 20132 Milan , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4834-2187","authenticated-orcid":false,"given":"Eustachio","family":"Agricola","sequence":"additional","affiliation":[{"name":"Cardiovascular Imaging Unit, Cardio-Thoracic-Vascular Department, IRCCS San Raffaele Scientific Institute , via Olgettina 60, 20132 Milan , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,2,17]]},"reference":[{"key":"2023072413345402200_jead015-B1","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/j.jacc.2016.10.068","article-title":"Tendyne global feasibility trial investigators. 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EAE\/ASE recommendations for image acquisition and display using three-dimensional echocardiography","volume":"25","author":"Lang","year":"2012","journal-title":"J Am Soc Echocardiogr"},{"key":"2023072413345402200_jead015-B11","doi-asserted-by":"crossref","first-page":"1878","DOI":"10.1093\/eurheartj\/ehv333","article-title":"Clinical trial design principles and endpoint definitions for transcatheter mitral valve repair and replacement: part 2: endpoint definitions: a consensus document from the mitral valve academic research consortium","volume":"36","author":"Stone","year":"2015","journal-title":"Eur Heart J"},{"key":"2023072413345402200_jead015-B12","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1016\/j.jcmg.2020.09.027","article-title":"Neo-LVOT and transcatheter mitral valve replacement: expert recommendations","volume":"14","author":"Reid","year":"2021","journal-title":"JACC Cardiovasc Imaging"},{"key":"2023072413345402200_jead015-B13","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1016\/j.recesp.2015.08.003","article-title":"Percutaneous transcatheter mitral valve replacement: patient-specific three-dimensional computer-based heart model and prototyping","volume":"68","author":"Vaquerizo","year":"2015","journal-title":"Rev Esp Cardiol (Engl Ed)"},{"key":"2023072413345402200_jead015-B14","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1016\/j.jcmg.2020.12.018","article-title":"Role of cardiac CT in Pre-procedure planning for transcatheter mitral valve replacement","volume":"14","author":"Ge","year":"2021","journal-title":"JACC Cardiovasc Imaging"},{"key":"2023072413345402200_jead015-B15","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.jcin.2018.12.001","article-title":"Predictors of left ventricular outflow tract obstruction after transcatheter mitral valve replacement","volume":"12","author":"Yoon","year":"2019","journal-title":"JACC Cardiovasc Interv"},{"key":"2023072413345402200_jead015-B16","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S0140-6736(86)90837-8","article-title":"Statistical methods for assessing agreement between two methods of clinical measurement","volume":"1","author":"Bland","year":"1986","journal-title":"Lancet"},{"key":"2023072413345402200_jead015-B17","doi-asserted-by":"crossref","first-page":"159","DOI":"10.2307\/2529310","article-title":"The measurement of observer agreement for categorical data","volume":"33","author":"Landis","year":"1977","journal-title":"Biometrics"},{"key":"2023072413345402200_jead015-B18","doi-asserted-by":"crossref","first-page":"e004176","DOI":"10.1161\/CIRCIMAGING.115.004176","article-title":"Three-Dimensional echocardiography compared with computed tomography to determine mitral Annulus size before transcatheter mitral valve implantation","volume":"9","author":"Mak","year":"2016","journal-title":"Circ Cardiovasc Imaging"},{"key":"2023072413345402200_jead015-B19","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1016\/j.jcmg.2015.08.004","article-title":"Multimodality imaging in the context of transcatheter mitral valve replacement: establishing consensus among modalities and disciplines","volume":"8","author":"Blanke","year":"2015","journal-title":"JACC Cardiovasc Imaging"},{"key":"2023072413345402200_jead015-B20","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1002\/ccd.27447","article-title":"Validating a prediction modeling tool for left ventricular outflow tract (LVOT) obstruction after transcatheter mitral valve replacement (TMVR)","volume":"92","author":"Wang","year":"2018","journal-title":"Catheter Cardiovasc Interv"},{"key":"2023072413345402200_jead015-B21","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.1148\/rg.2020200027","article-title":"CT For Pre- and postprocedural evaluation of transcatheter mitral valve replacement","volume":"40","author":"Ranganath","year":"2020","journal-title":"Radiographics"},{"key":"2023072413345402200_jead015-B22","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1093\/ehjci\/jez045","article-title":"Assessment of left ventricular outflow tract and aortic root: comparison of 2D and 3D transthoracic echocardiography with multidetector computed tomography","volume":"20","author":"Visby","year":"2019","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"2023072413345402200_jead015-B23","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1080\/14017431.2020.1761559","article-title":"Three-dimensional versus two-dimensional transthoracic echocardiography for left ventricular outflow tract measurements in severe aortic stenosis. A cross-sectional study using computer tomography and haegar sizers as reference","volume":"54","author":"Norum","year":"2020","journal-title":"Scand Cardiovasc J"},{"key":"2023072413345402200_jead015-B24","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1093\/ehjci\/jew328","article-title":"Three-dimensional echocardiographic quantification of the left-heart chambers using an automated adaptive analytics algorithm: multicentre validation study","volume":"19","author":"Medvedofsky","year":"2018","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"2023072413345402200_jead015-B25","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.jjcc.2018.02.017","article-title":"Superiority of novel automated assessment of aortic annulus by intraoperative three-dimensional transesophageal echocardiography in patients with severe aortic stenosis: comparison with conventional cross-sectional assessment","volume":"72","author":"Kato","year":"2018","journal-title":"J Cardiol"},{"key":"2023072413345402200_jead015-B26","doi-asserted-by":"crossref","first-page":"1854","DOI":"10.1016\/j.jcmg.2018.06.024","article-title":"3-Dimensional Echocardiography: latest developments and future directions","volume":"11","author":"Lang","year":"2018","journal-title":"JACC Cardiovasc Imaging"}],"container-title":["European Heart Journal - Cardiovascular Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ehjcimaging\/article-pdf\/24\/8\/1043\/50946269\/jead015.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ehjcimaging\/article-pdf\/24\/8\/1043\/50946269\/jead015.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,24]],"date-time":"2023-07-24T13:36:03Z","timestamp":1690205763000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ehjcimaging\/article\/24\/8\/1043\/7043512"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,17]]},"references-count":26,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2023,2,17]]},"published-print":{"date-parts":[[2023,7,24]]}},"URL":"https:\/\/doi.org\/10.1093\/ehjci\/jead015","relation":{},"ISSN":["2047-2404","2047-2412"],"issn-type":[{"value":"2047-2404","type":"print"},{"value":"2047-2412","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,8]]},"published":{"date-parts":[[2023,2,17]]}}}