{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T15:49:37Z","timestamp":1787845777655,"version":"build-2784847793"},"reference-count":37,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2023,5,17]],"date-time":"2023-05-17T00:00:00Z","timestamp":1684281600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,10,27]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>We aim to evaluate the clinical relevance and the prognostic value of arterial and venous renal Doppler in acute decompensated precapillary pulmonary hypertension (PH).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>The renal resistance index (RRI) and the Doppler-derived renal venous stasis index (RVSI) were monitored at admission and on Day 3 in a prospective cohort of precapillary PH patients managed in intensive care unit for acute right heart failure (RHF). The primary composite endpoint included death, circulatory assistance, urgent transplantation, or rehospitalization for acute RHF within 90 days following inclusion. Ninety-one patients were enrolled (58% female, age 58 \u00b1 16 years). The primary endpoint event occurred in 32 patients (33%). In univariate logistic regression analysis, variables associated with RRI higher than the median value were non-variable parameters (age and history of hypertension), congestion (right atrial pressure and renal pulse pressure), cardiac function [tricuspid annular plane systolic excursion (TAPSE) and left ventricular outflow tract- velocity time integral], systemic pressures and NT-proBNP. Variables associated with RVSI higher than the median value were congestion (high central venous pressure, right atrial pressure, and renal pulse pressure), right cardiac function (TAPSE), severe tricuspid regurgitation, and systemic pressures. Inotropic support was more frequently required in patients with high RRI (P = 0.01) or high RVSI (P = 0.003) at the time of admission. At Day 3, a RRI value &amp;lt;0.9 was associated with a better prognosis after adjusting to the estimated glomerular filtration rate.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Renal Doppler provides additional information to assess the severity of patients admitted to the intensive care unit for acute decompensated precapillary PH.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjci\/jead104","type":"journal-article","created":{"date-parts":[[2023,5,17]],"date-time":"2023-05-17T08:36:09Z","timestamp":1684312569000},"page":"1518-1527","source":"Crossref","is-referenced-by-count":6,"title":["Clinical relevance and prognostic value of renal Doppler in acute decompensated precapillary pulmonary hypertension"],"prefix":"10.1093","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9295-9344","authenticated-orcid":false,"given":"J\u00e9r\u00e9mie","family":"Pichon","sequence":"first","affiliation":[{"name":"Assistance Publique - H\u00f4pitaux de Paris (AP-HP), Service de Pneumologie et Soins Intensifs Respiratoires, H\u00f4pital Bic\u00eatre , 78 rue du g\u00e9n\u00e9ral Leclerc, 94270 Le Kremlin-Bic\u00eatre , France"},{"name":"INSERM UMR_S 999 \u00ab Pulmonary Hypertension: Pathophysiology and Novel Therapies \u00bb, H\u00f4pital Marie Lannelongue , 92350 Le Plessis-Robinson , France"},{"name":"Universit\u00e9 Paris-Saclay, Facult\u00e9 de M\u00e9decine , 94276 Le Kremlin Bic\u00eatre , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Roche","sequence":"additional","affiliation":[{"name":"Assistance Publique - H\u00f4pitaux de Paris (AP-HP), Service de Pneumologie et Soins Intensifs Respiratoires, H\u00f4pital Bic\u00eatre , 78 rue du g\u00e9n\u00e9ral Leclerc, 94270 Le Kremlin-Bic\u00eatre , France"},{"name":"INSERM UMR_S 999 \u00ab Pulmonary Hypertension: Pathophysiology and Novel Therapies \u00bb, H\u00f4pital Marie Lannelongue , 92350 Le Plessis-Robinson , France"},{"name":"Universit\u00e9 Paris-Saclay, Facult\u00e9 de M\u00e9decine , 94276 Le Kremlin Bic\u00eatre , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles","family":"Fauvel","sequence":"additional","affiliation":[{"name":"CHU Rouen, Department of Cardiology , F-76000 Rouen , France"},{"name":"Universit\u00e9 Rouen Normandie, Inserm U1096 , F-76000 Rouen , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ath\u00e9nais","family":"Boucly","sequence":"additional","affiliation":[{"name":"Assistance Publique - H\u00f4pitaux de Paris (AP-HP), Service de Pneumologie et Soins Intensifs Respiratoires, H\u00f4pital Bic\u00eatre , 78 rue du g\u00e9n\u00e9ral Leclerc, 94270 Le Kremlin-Bic\u00eatre , 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