{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T19:32:21Z","timestamp":1740166341416,"version":"3.37.3"},"reference-count":16,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2023,7,15]],"date-time":"2023-07-15T00:00:00Z","timestamp":1689379200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Funda\u00e7\u00e3o de Amparo a Pesquisa do Estado de S\u00e3o Paulo","award":["2011\/20876-2"],"award-info":[{"award-number":["2011\/20876-2"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,11,23]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>To analyse the association of myocardial oedema (ME), observed as high T2 signal intensity (HT2) in cardiac magnetic resonance imaging, with the release of cardiac biomarkers, ventricular ejection, and clinical outcomes after revascularization.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>Patients with stable coronary artery disease with the indication for revascularization were included. Biomarker levels [troponin I (cTnI) and creatine kinase MB (CK-MB)] and T2-weighted and late gadolinium enhancement (LGE) images were obtained before and after the percutaneous or surgical revascularization procedures. The association of HT2 with the levels of biomarkers, with and without LGE, evolution of left ventricular ejection fraction (LVEF), and 5-year clinical outcomes were assessed. A total of 196 patients were divided into 2 groups: Group 1 (HT2, 40) and Group 2 (no HT2, 156). Both peak cTnI (8.9 and 1.6 ng\/mL) and peak CK-MB values (44.7 and 12.1 ng\/mL) were significantly higher in Group 1. Based on the presence of new LGE, patients were stratified into Groups A (no HT2\/LGE, 149), B (HT2, 9), C (LGE, 7), and D (both HT2\/LGE, 31). The peak cTnI and CK-MB values were 1.5 and 12.0, 5.4 and 44.7, 5.0 and 18.3, and 9.8 and 42.8 ng\/mL in Groups A, B, C, and D, respectively, and were significantly different. The average LVEF decreased by 4.4% in Group 1 and increased by 2.2% in Group 2 (P = 0.057).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>ME after revascularization procedures was associated with increased release of cardiac necrosis biomarkers, and a trend towards a difference in LVEF, indicating a role of ME in cardiac injury after interventions.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjci\/jead171","type":"journal-article","created":{"date-parts":[[2023,7,14]],"date-time":"2023-07-14T12:05:28Z","timestamp":1689336328000},"page":"1700-1709","source":"Crossref","is-referenced-by-count":0,"title":["Abnormal release of cardiac biomarkers in the presence of myocardial oedema evaluated by cardiac magnetic resonance after uncomplicated revascularization procedures"],"prefix":"10.1093","volume":"24","author":[{"given":"Fernando Faglioni","family":"Ribas","sequence":"first","affiliation":[{"name":"Divis\u00e3o Cl\u00ednica Instituto do Cora\u00e7\u00e3o (InCor), Hospital das Cl\u00ednicas HCFMUSP, Faculdade de Medicina, Universidade de S\u00e3o Paulo , Rua Dr. Eneas de Carvalho Aguiar 44, AB floor, Room 114, Cerqueira C\u00e9sar, S\u00e3o Paulo 05403-000 , Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3166-6054","authenticated-orcid":false,"given":"Whady","family":"Hueb","sequence":"additional","affiliation":[{"name":"Divis\u00e3o Cl\u00ednica Instituto do Cora\u00e7\u00e3o (InCor), Hospital das Cl\u00ednicas HCFMUSP, Faculdade de Medicina, Universidade de S\u00e3o Paulo , Rua Dr. Eneas de Carvalho Aguiar 44, AB floor, Room 114, Cerqueira C\u00e9sar, S\u00e3o Paulo 05403-000 , Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo Cury","family":"Rezende","sequence":"additional","affiliation":[{"name":"Divis\u00e3o Cl\u00ednica Instituto do Cora\u00e7\u00e3o (InCor), Hospital das Cl\u00ednicas HCFMUSP, Faculdade de Medicina, Universidade de S\u00e3o Paulo , Rua Dr. Eneas de Carvalho Aguiar 44, AB floor, Room 114, Cerqueira C\u00e9sar, S\u00e3o Paulo 05403-000 , Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos Eduardo","family":"Rochitte","sequence":"additional","affiliation":[{"name":"Divis\u00e3o Cl\u00ednica Instituto do Cora\u00e7\u00e3o (InCor), Hospital das Cl\u00ednicas HCFMUSP, Faculdade de Medicina, Universidade de S\u00e3o Paulo , Rua Dr. Eneas de Carvalho Aguiar 44, AB floor, Room 114, Cerqueira C\u00e9sar, S\u00e3o Paulo 05403-000 , Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cesar Higa","family":"Nomura","sequence":"additional","affiliation":[{"name":"Divis\u00e3o Cl\u00ednica Instituto do Cora\u00e7\u00e3o (InCor), Hospital das Cl\u00ednicas HCFMUSP, Faculdade de Medicina, Universidade de S\u00e3o Paulo , Rua Dr. Eneas de Carvalho Aguiar 44, AB floor, Room 114, Cerqueira C\u00e9sar, S\u00e3o Paulo 05403-000 , Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandre Volney","family":"Villa","sequence":"additional","affiliation":[{"name":"Divis\u00e3o Cl\u00ednica Instituto do Cora\u00e7\u00e3o (InCor), Hospital das Cl\u00ednicas HCFMUSP, Faculdade de Medicina, Universidade de S\u00e3o Paulo , Rua Dr. Eneas de Carvalho Aguiar 44, AB floor, Room 114, Cerqueira C\u00e9sar, S\u00e3o Paulo 05403-000 , Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thamara Carvalho","family":"Morais","sequence":"additional","affiliation":[{"name":"Divis\u00e3o Cl\u00ednica Instituto do Cora\u00e7\u00e3o (InCor), Hospital das Cl\u00ednicas HCFMUSP, Faculdade de Medicina, Universidade de S\u00e3o Paulo , Rua Dr. Eneas de Carvalho Aguiar 44, AB floor, Room 114, Cerqueira C\u00e9sar, S\u00e3o Paulo 05403-000 , Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo Gomes","family":"Lima","sequence":"additional","affiliation":[{"name":"Divis\u00e3o Cl\u00ednica Instituto do Cora\u00e7\u00e3o (InCor), Hospital das Cl\u00ednicas HCFMUSP, Faculdade de Medicina, Universidade de S\u00e3o Paulo , Rua Dr. Eneas de Carvalho Aguiar 44, AB floor, Room 114, Cerqueira C\u00e9sar, S\u00e3o Paulo 05403-000 , Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gustavo Andr\u00e9","family":"Boeing Boros","sequence":"additional","affiliation":[{"name":"Divis\u00e3o Cl\u00ednica Instituto do Cora\u00e7\u00e3o (InCor), Hospital das Cl\u00ednicas HCFMUSP, Faculdade de Medicina, Universidade de S\u00e3o Paulo , Rua Dr. Eneas de Carvalho Aguiar 44, AB floor, Room 114, Cerqueira C\u00e9sar, S\u00e3o Paulo 05403-000 , Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matheus de Oliveira Laterza","family":"Ribeiro","sequence":"additional","affiliation":[{"name":"Divis\u00e3o Cl\u00ednica Instituto do Cora\u00e7\u00e3o (InCor), Hospital das Cl\u00ednicas HCFMUSP, Faculdade de Medicina, Universidade de S\u00e3o Paulo , Rua Dr. Eneas de Carvalho Aguiar 44, AB floor, Room 114, Cerqueira C\u00e9sar, S\u00e3o Paulo 05403-000 , Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaime Paula Pessoa","family":"Linhares-Filho","sequence":"additional","affiliation":[{"name":"Divis\u00e3o Cl\u00ednica Instituto do Cora\u00e7\u00e3o (InCor), Hospital das Cl\u00ednicas HCFMUSP, Faculdade de Medicina, Universidade de S\u00e3o Paulo , Rua Dr. Eneas de Carvalho Aguiar 44, AB floor, Room 114, Cerqueira C\u00e9sar, S\u00e3o Paulo 05403-000 , Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anderson Roberto","family":"Dallazen","sequence":"additional","affiliation":[{"name":"Divis\u00e3o Cl\u00ednica Instituto do Cora\u00e7\u00e3o (InCor), Hospital das Cl\u00ednicas HCFMUSP, Faculdade de Medicina, Universidade de S\u00e3o Paulo , Rua Dr. Eneas de Carvalho Aguiar 44, AB floor, Room 114, Cerqueira C\u00e9sar, S\u00e3o Paulo 05403-000 , Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafael Rocha Mol","family":"Silva","sequence":"additional","affiliation":[{"name":"Divis\u00e3o Cl\u00ednica Instituto do Cora\u00e7\u00e3o (InCor), Hospital das Cl\u00ednicas HCFMUSP, Faculdade de Medicina, Universidade de S\u00e3o Paulo , Rua Dr. Eneas de Carvalho Aguiar 44, AB floor, Room 114, Cerqueira C\u00e9sar, S\u00e3o Paulo 05403-000 , Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose Antonio","family":"Franchini Ramires","sequence":"additional","affiliation":[{"name":"Divis\u00e3o Cl\u00ednica Instituto do Cora\u00e7\u00e3o (InCor), Hospital das Cl\u00ednicas HCFMUSP, Faculdade de Medicina, Universidade de S\u00e3o Paulo , Rua Dr. Eneas de Carvalho Aguiar 44, AB floor, Room 114, Cerqueira C\u00e9sar, S\u00e3o Paulo 05403-000 , 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