{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T03:53:27Z","timestamp":1793073207955,"version":"4.5.0"},"reference-count":29,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,12,21]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>In \u223c5\u201315% of all cases of acute coronary syndromes (ACS) have unobstructed coronaries on angiography. Cardiac magnetic resonance (CMR) has proven useful to identify in most patients the underlying diagnosis associated with this presentation. However, the role of CMR to reclassify patients from the initial suspected condition has not been clarified. The aim of this study was to assess the proportion of patients with suspected MINOCA, or non-MINOCA, that CMR reclassifies with an alternative diagnosis from the original clinical suspicion.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>A retrospective cohort of patients in a tertiary cardiology centre was identified from a registry database. Patients who were referred for CMR for investigation of suspected MINOCA, and a diagnosis pre- and post-CMR was recorded to determine the proportion of diagnoses reclassified. A total of 888 patients were identified in the registry. CMR reclassified diagnosis in 78% of patients. Diagnosis of MINOCA was confirmed in only 243 patients (27%), whilst most patients had an alternative diagnosis (73%): myocarditis n = 217 (24%), Takotsubo syndrome n = 115 (13%), cardiomyopathies n = 97 (11%), and normal CMR\/non-specific n = 216 (24%).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>In a large single-centre cohort of patients presenting with ACS and unobstructed coronary arteries, most patients had a non-MINOCA diagnosis (73%) (myocarditis, Takotsubo, cardiomyopathies, or normal CMR\/non-specific findings), whilst only a minority had confirmed MINOCA (27%). Performing CMR led to reclassifying patients\u2019 diagnosis in 78% of cases, thus confirming its important clinical role and underscoring the clinical challenge in diagnosing MINOCA and non MINOCA conditions.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjci\/jead182","type":"journal-article","created":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T11:51:54Z","timestamp":1690890714000},"page":"8-15","source":"Crossref","is-referenced-by-count":38,"title":["CMR reclassifies the majority of patients with suspected MINOCA and non MINOCA"],"prefix":"10.1093","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8117-3637","authenticated-orcid":false,"given":"Kate","family":"Liang","sequence":"first","affiliation":[{"name":"Bristol Medical School, Faculty of Health Sciences, University of Bristol , Senate House, Tyndall Avenue, Bristol, BS8 1TH , UK"},{"name":"Department of Cardiology, Bristol Heart Institute, University Hospitals Bristol and Weston NHS Trust , Upper Maudlin Street, Bristol, BS2 8HY , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giandomenico","family":"Bisaccia","sequence":"additional","affiliation":[{"name":"Royal Brompton and Harefield Hospitals, Guys\u2019 and St Thomas NHS Trust, Royal Brompton Hospital , Sydney Street, Greater London, SW3 6NP , UK"},{"name":"Department of Neuroscience, Imaging and Clinical Sciences, G. d\u2019Annunzio University of Chieti-Pescara , 66100 Chieti , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabella","family":"Leo","sequence":"additional","affiliation":[{"name":"Royal Brompton and Harefield Hospitals, Guys\u2019 and St Thomas NHS Trust, Royal Brompton Hospital , Sydney Street, Greater London, SW3 6NP , UK"},{"name":"Department of Experimental and Clinical Medicine, Magna Graecia University , 88100 Catanzaro , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew G L","family":"Williams","sequence":"additional","affiliation":[{"name":"Bristol Medical School, Faculty of Health Sciences, University of Bristol , Senate House, Tyndall Avenue, Bristol, BS8 1TH , UK"},{"name":"Department of Cardiology, Bristol Heart Institute, University Hospitals Bristol and Weston NHS Trust , Upper Maudlin Street, Bristol, BS2 8HY , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8688-5326","authenticated-orcid":false,"given":"Amardeep","family":"Dastidar","sequence":"additional","affiliation":[{"name":"Bristol Medical School, Faculty of Health Sciences, University of Bristol , Senate House, Tyndall Avenue, Bristol, BS8 1TH , UK"},{"name":"Department of Cardiology, Bristol Heart Institute, University Hospitals Bristol and Weston NHS Trust , Upper Maudlin Street, Bristol, BS2 8HY , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julian W","family":"Strange","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Bristol Heart Institute, University Hospitals Bristol and Weston NHS Trust , Upper Maudlin Street, Bristol, BS2 8HY , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Sammut","sequence":"additional","affiliation":[{"name":"Bristol Medical School, Faculty of Health Sciences, University of Bristol , Senate House, Tyndall Avenue, Bristol, BS8 1TH , UK"},{"name":"Department of Cardiology, Bristol Heart Institute, University Hospitals Bristol and Weston NHS Trust , Upper Maudlin Street, Bristol, BS2 8HY , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas W","family":"Johnson","sequence":"additional","affiliation":[{"name":"Bristol Medical School, Faculty of Health Sciences, University of Bristol , Senate House, Tyndall Avenue, Bristol, BS8 1TH , UK"},{"name":"Department of Cardiology, Bristol Heart Institute, University Hospitals Bristol 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