{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T10:42:09Z","timestamp":1772188929312,"version":"3.50.1"},"reference-count":24,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T00:00:00Z","timestamp":1700179200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100013709","name":"European Association of Cardiovascular Imaging","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013709","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,3,27]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>Permanent pacemaker (PM) implantation is common after transcatheter aortic valve implantation (TAVI). Left ventricular mechanical dispersion (MeDi) by speckle tracking echocardiography is a marker of fibrosis that causes alterations in the conduction system. We hypothesized that MeDi can be a predictor of the need for PM implantation after TAVI.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>Consecutively, 200 TAVI patients were enrolled. Transthoracic echocardiography and electrocardiography examinations were recorded before TAVI to evaluate global longitudinal strain (GLS), MeDi, and conduction disturbances. PM implantation information was obtained 3 months after TAVI. Patients were stratified into PM or no PM group. Mean age was 80 + 7 years (44% women). Twenty-nine patients (16%) received PM. MeDi, QRS duration, existence of right bundle branch abnormality (RBBB), and first-degree atrioventricular (AV) block were significantly different between groups. MeDi was 57 \u00b1 15\u2005ms and 48 \u00b1 12\u2005ms in PM and no PM groups, respectively (P &amp;lt; 0.001). In multivariate analysis, MeDi predicted the need for PM after TAVI independently of GLS, QRS duration, RBBB, and first-degree AV block [odds ratio (OR): 1.73, 95% confidence interval (CI): 1.22\u20132.45] with an area under the curve (AUC) of 0.68 in receiver operating characteristic (ROC) curves. Moreover, RBBB was an independent predictor of PM need after TAVI (OR: 8.98, 95% CI: 1.78\u201345.03). When added to RBBB, MeDi had an incremental predictive value with an AUC of 0.73 in ROC curves (P = 0.01).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>MeDi may be used as an echocardiographic functional predictor of the need for PM after TAVI.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjci\/jead315","type":"journal-article","created":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T18:30:17Z","timestamp":1700245817000},"page":"539-547","source":"Crossref","is-referenced-by-count":5,"title":["Left ventricular mechanical dispersion as a predictor of the need for pacemaker implantation after transcatheter aortic valve implantation: MeDiPace TAVI study"],"prefix":"10.1093","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4350-7365","authenticated-orcid":false,"given":"Esra","family":"Kaya","sequence":"first","affiliation":[{"name":"Department of Cardiology, Clinic of Heart, Lung and Vessel Disease, Rikshospitalet, Oslo University Hospital , Sognsvannsveien 20, 0372 Oslo , Norway"},{"name":"Clinic of Heart, Lung and Vessel Disease, Rikshospitalet, Institude for Surgical Research, Oslo University Hospital , Sognsvannsveien 20,0372 Oslo , Norway"},{"name":"PROCARDIO-Center for Innovation, Clinic of Heart, Lung and Vessel Disease, Rikshospitalet, Oslo University Hospital , Oslo , Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristoffer","family":"Andresen","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Clinic of Heart, Lung and Vessel Disease, Rikshospitalet, Oslo University Hospital , Sognsvannsveien 20, 0372 Oslo , Norway"},{"name":"PROCARDIO-Center for Innovation, Clinic of Heart, Lung and Vessel Disease, Rikshospitalet, Oslo University Hospital , Oslo , Norway"},{"name":"Institude of Clinical Medicine, University of Oslo , Blindern 0318, Oslo , Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00d8yvind H","family":"Lie","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Clinic of Heart, Lung and Vessel Disease, Rikshospitalet, Oslo University Hospital , Sognsvannsveien 20, 0372 Oslo , Norway"},{"name":"PROCARDIO-Center for Innovation, Clinic of Heart, Lung and Vessel Disease, Rikshospitalet, Oslo University Hospital , Oslo , Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lars","family":"Aaberge","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Clinic of Heart, Lung and Vessel Disease, Rikshospitalet, Oslo University Hospital , Sognsvannsveien 20, 0372 Oslo , Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristina H","family":"Haugaa","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Clinic of Heart, Lung and Vessel Disease, Rikshospitalet, Oslo University Hospital , Sognsvannsveien 20, 0372 Oslo , Norway"},{"name":"PROCARDIO-Center for Innovation, Clinic of Heart, Lung and Vessel Disease, Rikshospitalet, Oslo University Hospital , Oslo , Norway"},{"name":"Institude of Clinical Medicine, University of Oslo , Blindern 0318, Oslo , Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3800-765X","authenticated-orcid":false,"given":"Thor","family":"Edvardsen","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Clinic of Heart, Lung and Vessel Disease, Rikshospitalet, Oslo University Hospital , Sognsvannsveien 20, 0372 Oslo , Norway"},{"name":"PROCARDIO-Center for Innovation, Clinic of Heart, Lung and Vessel Disease, Rikshospitalet, Oslo University Hospital , Oslo , Norway"},{"name":"Institude of Clinical Medicine, University of Oslo , Blindern 0318, Oslo , Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4787-8841","authenticated-orcid":false,"given":"Helge","family":"Skulstad","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Clinic of Heart, Lung and Vessel Disease, Rikshospitalet, Oslo University Hospital , Sognsvannsveien 20, 0372 Oslo , Norway"},{"name":"Clinic of Heart, Lung and Vessel Disease, Rikshospitalet, Institude for Surgical Research, Oslo University Hospital , Sognsvannsveien 20,0372 Oslo , Norway"},{"name":"PROCARDIO-Center for Innovation, Clinic of Heart, Lung and Vessel Disease, Rikshospitalet, Oslo University Hospital , Oslo , Norway"},{"name":"Institude of Clinical Medicine, University of Oslo , Blindern 0318, Oslo , 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