{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T16:19:27Z","timestamp":1791389967071,"version":"4.3.3"},"reference-count":20,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2024,1,25]],"date-time":"2024-01-25T00:00:00Z","timestamp":1706140800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Berta-Ottenstein-Programme for Advanced Clinician Scientists, Faculty of Medicine"},{"DOI":"10.13039\/501100002714","name":"University of Freiburg","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002714","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,5,31]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>To identify radiographic differences between patients with uncomplicated and complicated descending aortic dissections.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>Between April 2009 and July 2021, 209 patients with acute descending aortic dissections were analysed as complicated (malperfusion, rupture, diameter progress, and diameter \u2265 55\u2005mm) or uncomplicated. Detailed CTA measurements (slice thickness \u2264 3\u2005mm) were taken in multiplanar reconstruction. A composite endpoint (early aortic failure) was defined as reoperation, diameter progression, and early mortality. Seventy-seven patients were female (36.8%) [complicated n = 27 (36.5%); uncomplicated n = 50 (37.0%) P = 1.00]. Seventy-four (35%) patients were categorized as morphologically complicated, and 135 (65%) as uncomplicated. In patients with complicated dissections, the dissection extended more frequently to the aortic bifurcation (P = 0.044), the coeliac trunk (P = 0.003), the superior mesenteric artery (P = 0.007), and both iliac arteries (P &amp;lt; 0.001) originated less frequently from the true lumen. The length of the most proximal communication (entry) in type B aortic dissection was longer, 14.0\u2005mm [12.0\u2005mm; 27.0\u2005mm] vs. 6.0\u2005mm [4,0\u2005mm; 13.0\u2005mm] in complicated cases (P = 0.005). Identified risk factors for adverse aortic events were connective tissue disease [HR 8.0 (1.9\u201333.7 95% CI HR)], length of the aortic arch [HR 4.7 (1.5\u201315.1 95% CI HR)], a false lumen diameter &amp;gt; 19.38\u2005mm [HR 3.389 (1.1\u201310.2 95% CI HR)], and origin of the inferior mesenteric artery from the false lumen [HR 4.2 (1.0\u20135.5 95% CI HR)].<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>We identified significant morphological differences and predictors for adverse events in patients presenting complicated and uncomplicated descending dissections. Our morphological findings will help guide future aortic therapies, taking a tailored patient approach.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjci\/jeae030","type":"journal-article","created":{"date-parts":[[2024,1,25]],"date-time":"2024-01-25T09:49:04Z","timestamp":1706176144000},"page":"867-877","source":"Crossref","is-referenced-by-count":11,"title":["Radiographic complicated and uncomplicated descending aortic dissections: aortic morphological differences by CT angiography and risk factor analysis"],"prefix":"10.1093","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6263-9123","authenticated-orcid":false,"given":"Tim","family":"Berger","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, University Heart Centre Freiburg, University Medical Centre Freiburg , S\u00fcdring 15, 79189 Bad Krozingen, Freiburg , Germany"},{"name":"Faculty of Medicine, Albert-Ludwigs-University of Freiburg , Breisacher Strasse 153, 79110 Freiburg , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annika","family":"Maier","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, University Heart Centre Freiburg, University Medical Centre Freiburg , S\u00fcdring 15, 79189 Bad Krozingen, Freiburg , Germany"},{"name":"Faculty of Medicine, Albert-Ludwigs-University of Freiburg , Breisacher Strasse 153, 79110 Freiburg , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Kletzer","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, University Heart Centre Freiburg, University Medical Centre Freiburg , S\u00fcdring 15, 79189 Bad Krozingen, Freiburg , Germany"},{"name":"Faculty of Medicine, Albert-Ludwigs-University of Freiburg , Breisacher Strasse 153, 79110 Freiburg , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher L","family":"Schlett","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Albert-Ludwigs-University of Freiburg , Breisacher Strasse 153, 79110 Freiburg , Germany"},{"name":"Department of Diagnostic and Interventional Radiology, University Medical Centre Freiburg , Freiburg , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stoyan","family":"Kondov","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, University Heart Centre Freiburg, University Medical Centre Freiburg , S\u00fcdring 15, 79189 Bad Krozingen, Freiburg , Germany"},{"name":"Faculty of Medicine, Albert-Ludwigs-University of Freiburg , Breisacher Strasse 153, 79110 Freiburg , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Czerny","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, University Heart Centre Freiburg, University Medical Centre Freiburg , S\u00fcdring 15, 79189 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