{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T05:22:33Z","timestamp":1793251353642,"version":"4.5.0"},"reference-count":33,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Fondation Coeur et Recherche"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,7,31]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>Tricuspid annular plane systolic excursion over systolic pulmonary artery pressure (TAPSE\/sPAP) assessed by echocardiography appears to be a good non-invasive approach for right ventricular to pulmonary artery coupling assessment. We aimed to assess the in-hospital prognostic value of TAPSE\/sPAP among patients hospitalized for acute heart failure (AHF).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and results<\/jats:title>\n                  <jats:p>In total, 333 consecutive patients (mean age 68 \u00b1 14 years, 70% of male, mean left ventricular ejection fraction 44 \u00b1 16%) were hospitalized for AHF across 39 French cardiology departments, with TAPSE\/sPAP measured by echocardiography within the first 24\u2005h of hospitalization were included in this prospective study. The primary outcome was in-hospital major adverse cardiovascular events (MACEs) defined as all-cause death, resuscitated cardiac arrest or cardiogenic shock and occurred in 50 (15%) patients. Using receiver operating characteristic curve analysis, the best TAPSE\/sPAP threshold for in-hospital MACEs was 0.40\u2005mm\/mmHg. TAPSE\/sPAP &amp;lt; 0.40\u2005mm\/mmHg was independently associated with in-hospital MACEs, even after adjustment with comorbidities [odds ratio (OR): 3.75, 95% CI (1.87\u20137.93), P &amp;lt; 0.001], clinical severity [OR: 2.80, 95% CI (1.36\u20135.95), P = 0.006]. Using a 1:1 propensity-matched population, TAPSE\/sPAP ratio &amp;lt; 0.40 was associated with a higher rate of in-hospital MACEs [OR: 2.98, 95% CI (1.53\u20136.12), P = 0.002]. After adjustment, TAPSE\/sPAP &amp;lt; 0.40 showed the best improvement in model discrimination and reclassification above traditional prognostic factors (C-statistic improvement: 0.05; \u03c72 improvement: 14.4; likelihood-ratio test P &amp;lt; 0.001). These results were consistent in an external validation cohort of 133 patients.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>TAPSE\/sPAP &amp;lt; 0.40\u2005mm\/mmHg assessed by an early echocardiography during an AHF episode is independently associated with in-hospital MACEs suggesting enhanced close monitoring and strengthened heart failure-specific care in these patients.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Trial Registration<\/jats:title>\n                  <jats:p>ClinicalTrials.gov Identifier: NCT05063097<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjci\/jeae059","type":"journal-article","created":{"date-parts":[[2024,3,2]],"date-time":"2024-03-02T01:40:50Z","timestamp":1709343650000},"page":"1099-1108","source":"Crossref","is-referenced-by-count":23,"title":["In-hospital prognostic value of TAPSE\/sPAP in patients hospitalized for acute heart failure"],"prefix":"10.1093","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6243-2544","authenticated-orcid":false,"given":"Charles","family":"Fauvel","sequence":"first","affiliation":[{"name":"Department of Cardiology, CHU Rouen, Inserm U1096, Univ Rouen Normandie , 1 rue de Germont, F-76000 Rouen , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Guillaume","family":"Dillinger","sequence":"additional","affiliation":[{"name":"Inserm U-942, Assistance Publique-H\u00f4pitaux de Paris, H\u00f4pital Lariboisi\u00e8re, Department of Cardiology, Universit\u00e9 de Paris Cit\u00e9 , 2 rue Ambroise Par\u00e9, 75010 Paris , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reza","family":"Rossanaly Vasram","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Felix-Guyon University Hospital , 11021 All. Des Topazes, Saint-Denis-de-la-R\u00e9union , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Bouleti","sequence":"additional","affiliation":[{"name":"Cardiology Department, Clinical Investigation Center (INSERM 1204), University Hospital of Poitiers , 2 Rue de la Mil\u00e9trie, 86000 Poitiers , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damien","family":"Logeart","sequence":"additional","affiliation":[{"name":"Inserm U-942, Assistance Publique-H\u00f4pitaux de Paris, H\u00f4pital Lariboisi\u00e8re, Department of Cardiology, Universit\u00e9 de Paris Cit\u00e9 , 2 rue Ambroise Par\u00e9, 75010 Paris , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois","family":"Roubille","sequence":"additional","affiliation":[{"name":"Department of Cardiology, CHU Montpellier , 191 Av. du Doyen Gaston Giraud, 34295 Montpellier , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8147-9265","authenticated-orcid":false,"given":"Christophe","family":"Meune","sequence":"additional","affiliation":[{"name":"Department of Cardiology, H\u00f4pital Avicenne, Assistance Publique-H\u00f4pitaux de Paris , 125 Rue de Stalingrad, 93000 Bobigny , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Ohlmann","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Nouvel H\u00f4pital Civil, Strasbourg University Hospital , 1 place de l'H\u00f4pital, Strasbourg , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Bonnefoy-Coudraz","sequence":"additional","affiliation":[{"name":"Intensive Cardiological Care Division, Louis Pradel Hospital, Hospices Civils de Lyon , 59 Bd Pinel, Bron , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franck","family":"Albert","sequence":"additional","affiliation":[{"name":"Service de Cardiologie, Centre Hospitalier de Chartres , 4 rue Claude Bernard, 28360 Le Coudray , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabir","family":"Attou","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Caen University Hospital , Av. de la C\u00f4te de Nacre,14000 Caen , France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marouane","family":"Boukhris","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Limoges University Hospital , 2 Av. 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