{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T02:45:46Z","timestamp":1769827546267,"version":"3.49.0"},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T00:00:00Z","timestamp":1761868800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,30]]},"DOI":"10.1093\/ehjci\/jeaf303","type":"journal-article","created":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T13:14:54Z","timestamp":1761830094000},"page":"10-11","source":"Crossref","is-referenced-by-count":0,"title":["A little calcium goes a long way: rethinking early calcific aortic valve disease"],"prefix":"10.1093","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8924-740X","authenticated-orcid":false,"given":"Marie-Annick","family":"Clavel","sequence":"first","affiliation":[{"name":"Institut Universitaire de Cardiologie et de Pneumologie de Qu\u00e9bec, Universit\u00e9 Laval , 2725 Chemin Sainte-Foy, Qu\u00e9bec city, Qu\u00e9bec G1V-4G5 ,","place":["Canada"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,10,31]]},"reference":[{"key":"2026013009121077700_jeaf303-B1","doi-asserted-by":"crossref","first-page":"2329","DOI":"10.1016\/j.jacc.2013.08.1621","article-title":"The complex nature of discordant severe calcified aortic valve disease grading: new insights from combined Doppler-echocardiographic and computed tomographic study","volume":"62","author":"Clavel","year":"2013","journal-title":"J Am Coll Cardiol"},{"key":"2026013009121077700_jeaf303-B2","doi-asserted-by":"crossref","first-page":"2852","DOI":"10.1016\/j.jacc.2014.04.018","article-title":"The prevalence, incidence, progression, and risks of aortic valve sclerosis: a systematic review and meta-analysis","volume":"63","author":"Coffey","year":"2014","journal-title":"J Am Coll Cardiol"},{"key":"2026013009121077700_jeaf303-B3","first-page":"1","article-title":"Impact of age on aortic valve calcium progression and risk for aortic stenosis: multi-ethnic study of atherosclerosis","volume":"27","author":"Marrero","year":"2026","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"2026013009121077700_jeaf303-B4","doi-asserted-by":"crossref","first-page":"2096","DOI":"10.1016\/j.jacc.2017.02.037","article-title":"Impact of aortic valve calcification and sex on hemodynamic progression and clinical outcomes in AS","volume":"69","author":"Tastet","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"2026013009121077700_jeaf303-B5","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1136\/heartjnl-2014-307154","article-title":"Haemodynamic and anatomic progression of aortic stenosis","volume":"101","author":"Nguyen","year":"2015","journal-title":"Heart"},{"key":"2026013009121077700_jeaf303-B6","doi-asserted-by":"crossref","first-page":"e013165","DOI":"10.1161\/CIRCIMAGING.121.013165","article-title":"Sex differences in factors associated with progression of aortic valve calcification in the general population","volume":"15","author":"Diederichsen","year":"2022","journal-title":"Circ Cardiovasc Imaging"},{"key":"2026013009121077700_jeaf303-B7","doi-asserted-by":"crossref","first-page":"e015610","DOI":"10.1161\/JAHA.119.015610","article-title":"Age, sex, and valve phenotype differences in fibro-calcific remodeling of calcified aortic valve","volume":"9","author":"Voisine","year":"2020","journal-title":"J Am Heart Assoc"},{"key":"2026013009121077700_jeaf303-B8","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1093\/ehjci\/jew013","article-title":"Systolic hypertension and progression of aortic valve calcification in patients with aortic stenosis: results from the PROGRESSA study","volume":"18","author":"Tastet","year":"2017","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"2026013009121077700_jeaf303-B9","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1016\/j.jacc.2015.07.020","article-title":"Oxidized phospholipids, lipoprotein(a), and progression of calcific aortic valve stenosis","volume":"66","author":"Capoulade","year":"2015","journal-title":"J Am Coll Cardiol"}],"container-title":["European Heart Journal - Cardiovascular Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ehjcimaging\/advance-article-pdf\/doi\/10.1093\/ehjci\/jeaf303\/65050637\/jeaf303.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ehjcimaging\/article-pdf\/27\/1\/10\/65050637\/jeaf303.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ehjcimaging\/article-pdf\/27\/1\/10\/65050637\/jeaf303.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T14:12:20Z","timestamp":1769782340000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ehjcimaging\/article\/27\/1\/10\/8307562"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,31]]},"references-count":9,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,10,31]]},"published-print":{"date-parts":[[2026,1,30]]}},"URL":"https:\/\/doi.org\/10.1093\/ehjci\/jeaf303","relation":{},"ISSN":["2047-2404","2047-2412"],"issn-type":[{"value":"2047-2404","type":"print"},{"value":"2047-2412","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,1]]},"published":{"date-parts":[[2025,10,31]]}}}