{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T16:49:44Z","timestamp":1793292584292,"version":"4.5.0"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2018,12,1]],"date-time":"2018-12-01T00:00:00Z","timestamp":1543622400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,5,1]]},"DOI":"10.1093\/ehjci\/jey178","type":"journal-article","created":{"date-parts":[[2018,10,30]],"date-time":"2018-10-30T04:41:46Z","timestamp":1540874506000},"page":"565-573","source":"Crossref","is-referenced-by-count":17,"title":["Natural history of bivalvular functional regurgitation"],"prefix":"10.1093","volume":"20","author":[{"given":"Philipp E","family":"Bartko","sequence":"first","affiliation":[{"name":"Department of Internal Medicine II, Medical University of Vienna, Waehringer Guertel 18-20, A Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrike","family":"Arfsten","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine II, Medical University of Vienna, Waehringer Guertel 18-20, A Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregor","family":"Heitzinger","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine II, Medical University of Vienna, Waehringer Guertel 18-20, A Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noemi","family":"Pavo","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine II, Medical University of Vienna, Waehringer Guertel 18-20, A Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Max-Paul","family":"Winter","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine II, Medical University of Vienna, Waehringer Guertel 18-20, A Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aurel","family":"Toma","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine II, Medical University of Vienna, Waehringer Guertel 18-20, A Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guido","family":"Strunk","sequence":"additional","affiliation":[{"name":"FH Campus Vienna and Complexity Research, Favoritenstra\u00dfe 226, A Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Hengstenberg","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine II, Medical University of Vienna, Waehringer Guertel 18-20, A Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"H\u00fclsmann","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine II, Medical University of Vienna, Waehringer Guertel 18-20, A Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georg","family":"Goliasch","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine II, Medical University of Vienna, Waehringer Guertel 18-20, A Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2018,12,1]]},"reference":[{"key":"2019042304540375200_jey178-B1","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1093\/eurheartj\/ehx402","article-title":"Refining the prognostic impact of functional mitral regurgitation in chronic heart failure","volume":"39","author":"Goliasch","year":"2018","journal-title":"Eur Heart J"},{"key":"2019042304540375200_jey178-B2","doi-asserted-by":"crossref","first-page":"1675","DOI":"10.1136\/hrt.2011.225789","article-title":"Independent prognostic value of functional mitral regurgitation in patients with heart failure. A quantitative analysis of 1256 patients with ischaemic and non-ischaemic dilated cardiomyopathy","volume":"97","author":"Rossi","year":"2011","journal-title":"Heart"},{"key":"2019042304540375200_jey178-B3","doi-asserted-by":"crossref","first-page":"1826","DOI":"10.1161\/01.CIR.96.6.1826","article-title":"Integrated mechanism for functional mitral regurgitation: leaflet restriction versus coapting force: in vitro studies","volume":"96","author":"He","year":"1997","journal-title":"Circulation"},{"key":"2019042304540375200_jey178-B4","doi-asserted-by":"crossref","first-page":"2739","DOI":"10.1093\/eurheartj\/ehx391","article-title":"ESC\/EACTS Guidelines for the management of valvular heart disease","volume":"38","author":"Baumgartner","year":"2017","journal-title":"Eur Heart J"},{"key":"2019042304540375200_jey178-B5","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1093\/eurheartj\/ehw128","article-title":"2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: the task force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC)Developed with the special contribution of the Heart Failure Association (HFA) of the ESC","volume":"37","author":"Ponikowski","year":"2016","journal-title":"Eur Heart J"},{"key":"2019042304540375200_jey178-B6","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1016\/S0140-6736(16)00558-4","article-title":"Mitral valve disease\u2014current management and future challenges","volume":"387","author":"Nishimura","year":"2016","journal-title":"Lancet"},{"key":"2019042304540375200_jey178-B7","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/j.jacc.2007.07.093","article-title":"Mitral regurgitation augments post-myocardial infarction remodeling failure of hypertrophic compensation","volume":"51","author":"Beeri","year":"2008","journal-title":"J Am Coll Cardiol"},{"key":"2019042304540375200_jey178-B8","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1016\/j.yjmcc.2009.06.001","article-title":"Extracellular matrix remodeling during the progression of volume overload-induced heart failure","volume":"48","author":"Hutchinson","year":"2010","journal-title":"J Mol Cell Cardiol"},{"key":"2019042304540375200_jey178-B9","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1067\/mhj.2002.123575","article-title":"Prognostic significance of mitral regurgitation and tricuspid regurgitation in patients with left ventricular systolic dysfunction","volume":"144","author":"Koelling","year":"2002","journal-title":"Am Heart J"},{"key":"2019042304540375200_jey178-B10","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1016\/S0002-9149(98)00624-9","article-title":"Usefulness of echocardiographic determined tricuspid regurgitation in predicting event-free survival in severe heart failure secondary to idiopathic-dilated cardiomyopathy or to ischemic cardiomyopathy","volume":"82","author":"Hung","year":"1998","journal-title":"Am J Cardiol"},{"key":"2019042304540375200_jey178-B11","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.jacc.2003.09.036","article-title":"Impact of tricuspid regurgitation on long-term survival","volume":"43","author":"Nath","year":"2004","journal-title":"J Am Coll Cardiol"},{"key":"2019042304540375200_jey178-B12","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1093\/eurheartj\/ehs465","article-title":"Impact of tricuspid regurgitation on survival in patients with chronic heart failure: unexpected findings of a long-term observational study","volume":"34","author":"Neuhold","year":"2013","journal-title":"Eur Heart J"},{"key":"2019042304540375200_jey178-B13","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1111\/j.1540-8175.2008.00823.x","article-title":"Reduction in mitral regurgitation in patients undergoing cardiac resynchronization treatment: assessment of predictors by two-dimensional radial strain echocardiography","volume":"26","author":"Goland","year":"2009","journal-title":"Echocardiography"},{"key":"2019042304540375200_jey178-B14","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1093\/ejechocard\/jeq031","article-title":"European Association of Echocardiography recommendations for the assessment of valvular regurgitation. Part 2: mitral and tricuspid regurgitation (native valve disease)","volume":"11","author":"Lancellotti","year":"2010","journal-title":"Eur J Echocardiogr"},{"key":"2019042304540375200_jey178-B15","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1016\/S0140-6736(18)30473-2","article-title":"Outcome and undertreatment of mitral regurgitation: a community cohort study","volume":"391","author":"Dziadzko","year":"2018","journal-title":"Lancet"},{"key":"2019042304540375200_jey178-B16","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1161\/01.CIR.103.13.1759","article-title":"Ischemic mitral regurgitation: long-term outcome and prognostic implications with quantitative Doppler assessment","volume":"103","author":"Grigioni","year":"2001","journal-title":"Circulation"},{"key":"2019042304540375200_jey178-B17","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1093\/ehjci\/jey023","article-title":"Evolution of secondary mitral regurgitation","volume":"19","author":"Bartko","year":"2018","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"2019042304540375200_jey178-B18","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.athoracsur.2004.06.057","article-title":"Secondary tricuspid regurgitation or dilatation: which should be the criteria for surgical repair?","volume":"79","author":"Dreyfus","year":"2005","journal-title":"Ann Thorac Surg"},{"key":"2019042304540375200_jey178-B19","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1016\/j.jtcvs.2010.05.050","article-title":"Tricuspid annuloplasty prevents right ventricular dilatation and progression of tricuspid regurgitation in patients with tricuspid annular dilatation undergoing mitral valve repair","volume":"141","author":"Van de Veire","year":"2011","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2019042304540375200_jey178-B20","doi-asserted-by":"crossref","first-page":"e1680","DOI":"10.4244\/EIJV11I14A320","article-title":"Impact of percutaneous mitral valve repair using the MitraClip system on tricuspid regurgitation","volume":"11","author":"Frangieh","year":"2016","journal-title":"EuroIntervention"},{"key":"2019042304540375200_jey178-B21","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1016\/j.amjcard.2017.05.044","article-title":"Postprocedural changes of tricuspid regurgitation after MitraClip therapy for mitral regurgitation","volume":"120","author":"Toyama","year":"2017","journal-title":"Am J Cardiol"},{"key":"2019042304540375200_jey178-B22","doi-asserted-by":"crossref","first-page":"e1809","DOI":"10.4244\/EIJ-D-16-00850","article-title":"Impact of tricuspid valve regurgitation in surgical high-risk patients undergoing MitraClip implantation: results from the TRAMI registry","volume":"12","author":"Kalbacher","year":"2017","journal-title":"EuroIntervention"},{"key":"2019042304540375200_jey178-B23","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1007\/s00392-016-1062-1","article-title":"Impact of baseline tricuspid regurgitation on long-term clinical outcomes and survival after interventional edge-to-edge repair for mitral regurgitation","volume":"106","author":"Schueler","year":"2017","journal-title":"Clin Res Cardiol"},{"key":"2019042304540375200_jey178-B24","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1093\/ehjci\/jeu114","article-title":"Association of tricuspid regurgitation with clinical and echocardiographic outcomes after percutaneous mitral valve repair with the MitraClip System: 30-day and 12-month follow-up from the GRASP Registry","volume":"15","author":"Ohno","year":"2014","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"2019042304540375200_jey178-B25","doi-asserted-by":"crossref","first-page":"I288","DOI":"10.1161\/CIRCULATIONAHA.106.681114","article-title":"Early repair of moderate ischemic mitral regurgitation reverses left ventricular remodeling: a functional and molecular study","volume":"116","author":"Beeri","year":"2007","journal-title":"Circulation"},{"key":"2019042304540375200_jey178-B26","doi-asserted-by":"crossref","first-page":"S248","DOI":"10.1161\/CIRCULATIONAHA.112.000124","article-title":"Late repair of ischemic mitral regurgitation does not prevent left ventricular remodeling: importance of timing for beneficial repair","volume":"128","author":"Beaudoin","year":"2013","journal-title":"Circulation"},{"key":"2019042304540375200_jey178-B27","doi-asserted-by":"crossref","first-page":"2844","DOI":"10.1016\/j.jacc.2015.10.018","article-title":"Randomized comparison of percutaneous repair and surgery for mitral regurgitation: 5-year results of EVEREST II","volume":"66","author":"Feldman","year":"2015","journal-title":"J Am Coll Cardiol"},{"key":"2019042304540375200_jey178-B28","doi-asserted-by":"crossref","first-page":"2134","DOI":"10.1016\/j.jacc.2005.07.065","article-title":"Percutaneous mitral valve repair using the edge-to-edge technique: six-month results of the EVEREST Phase I Clinical Trial","volume":"46","author":"Feldman","year":"2005","journal-title":"J Am Coll Cardiol"},{"key":"2019042304540375200_jey178-B29","article-title":"Transcatheter mitral-valve repair in patients with heart failure","author":"Stone","journal-title":"N Engl J Med"},{"key":"2019042304540375200_jey178-B30","doi-asserted-by":"crossref","first-page":"1932","DOI":"10.1056\/NEJMoa1602003","article-title":"Two-year outcomes of surgical treatment of moderate ischemic mitral regurgitation","volume":"374","author":"Michler","year":"2016","journal-title":"N Engl J Med"}],"container-title":["European Heart Journal - Cardiovascular Imaging"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/ehjcimaging\/article-pdf\/20\/5\/565\/28496512\/jey178.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,23]],"date-time":"2019-04-23T08:55:58Z","timestamp":1556009758000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ehjcimaging\/article\/20\/5\/565\/5224510"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12,1]]},"references-count":30,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2018,12,1]]},"published-print":{"date-parts":[[2019,5,1]]}},"URL":"https:\/\/doi.org\/10.1093\/ehjci\/jey178","relation":{},"ISSN":["2047-2404","2047-2412"],"issn-type":[{"value":"2047-2404","type":"print"},{"value":"2047-2412","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2019,5]]},"published":{"date-parts":[[2018,12,1]]}}}