{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T05:25:23Z","timestamp":1769577923930,"version":"3.49.0"},"reference-count":16,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2020,4,24]],"date-time":"2020-04-24T00:00:00Z","timestamp":1587686400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Transcatheter aortic valve implantation operators have adapted to a less invasive technique by foregoing the use of general anaesthesia and transoesophageal echocardiography. This is known as a \u2018minimalist approach\u2019. This approach has yet to be explored in transcatheter mitral valve replacement (TMVR). Two patients with high perioperative risk underwent TMVR using only monitored conscious sedation (CS) and intracardiac echocardiography (ICE).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case summary<\/jats:title>\n                  <jats:p>The patients were symptomatic and required treatment of severe mitral regurgitation and severe mitral stenosis in a mitral valve ring and prosthetic mitral valve, respectively. With the use of an antegrade transseptal approach, the procedure was conducted under CS using ICE only. After placement of the prosthetic mitral valve, the valve was assessed by advancing the ICE catheter through the interatrial septal defect and no significant paravalvular leak occurred. In one case, ad hoc treatment of right to left shunting was successfully pursued. Valve function was excellent immediately and at 24\u2009h after implantation and resulted in significant haemodynamic improvement.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>With more TMVR cases being conducted, the \u2018minimalist approach\u2019 with CS and ICE may be considered in selected cases.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytaa058","type":"journal-article","created":{"date-parts":[[2020,4,24]],"date-time":"2020-04-24T16:15:51Z","timestamp":1587744951000},"page":"1-5","source":"Crossref","is-referenced-by-count":14,"title":["\u2018Minimalist approach\u2019 for transcatheter mitral valve replacement using intracardiac echocardiography and conscious sedation: a case series"],"prefix":"10.1093","volume":"4","author":[{"given":"Robert J","family":"Cubeddu","sequence":"first","affiliation":[{"name":"Department of Cardiology, Heart & Vascular Institute, Cleveland Clinic Florida, 2590 Cleveland Clinic Blvd, Weston, FL 33331, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8065-6525","authenticated-orcid":false,"given":"Abdullah","family":"Sarkar","sequence":"first","affiliation":[{"name":"Department of Cardiology, Heart & Vascular Institute, Cleveland Clinic Florida, 2590 Cleveland Clinic Blvd, Weston, FL 33331, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Viviana","family":"Navas","sequence":"first","affiliation":[{"name":"Department of Cardiology, Heart & Vascular Institute, Cleveland Clinic Florida, 2590 Cleveland Clinic Blvd, Weston, FL 33331, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4089-2202","authenticated-orcid":false,"given":"Jose L","family":"Navia","sequence":"first","affiliation":[{"name":"Department of Cardiology, Heart & Vascular Institute, Cleveland Clinic Florida, 2590 Cleveland Clinic Blvd, Weston, FL 33331, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2020,4,24]]},"reference":[{"key":"2020062620240928300_ytaa058-B1","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/j.jcin.2012.01.018","article-title":"Transfemoral aortic valve replacement with the Edwards SAPIEN and Edwards SAPIEN XT prosthesis using exclusively local anesthesia and fluoroscopic guidance: feasibility and 30-day outcomes","volume":"5","author":"Durand","year":"2012","journal-title":"JACC Cardiovasc Interv"},{"key":"2020062620240928300_ytaa058-B2","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1136\/heartjnl-2014-307351","article-title":"Early discharge after transfemoral transcatheter aortic valve implantation","volume":"101","author":"Barbanti","year":"2015","journal-title":"Heart"},{"key":"2020062620240928300_ytaa058-B3","first-page":"420","article-title":"Safety and efficacy of minimalist 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