{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T23:10:28Z","timestamp":1740179428627,"version":"3.37.3"},"reference-count":11,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2020,4,27]],"date-time":"2020-04-27T00:00:00Z","timestamp":1587945600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Due to ongoing left ventricular (LV) remodeling and consecutive geometric displacement of both papillary muscles, end-stage heart failure is frequently associated with relevant functional mitral regurgitation (FMR) Type IIIb. Treatment strategies of FMR and their prognostic impact are still controversial.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case summary<\/jats:title>\n                  <jats:p>We present a case of an 80-year-old patient who suffered from recurrent symptoms of congestive heart failure due to dilated cardiomyopathy and concomitant severe FMR. To specifically address severe tethering of both mitral leaflets heart team decision was to perform minimally invasive mitral valve repair (MVR) including a subannular LV remodeling procedure, instead of an interventional edge-to-edge repair (MitraClip\u00ae procedure). In addition to mitral valve ring annuloplasty, standardized relocation of both papillary muscles was performed successfully, leading to a complete resolution of mitral leaflet tethering. There were no procedural complications and the patient was discharged with an excellent functional result without residual mitral regurgitation. Furthermore, after 12 and 24\u2009months, he reported an increase of his functional exercise capacity and a remarkable reverse LV remodeling could be demonstrated.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>Novel subannular repair techniques, especially the relocation of both papillary muscles, specifically address severe leaflet tethering in FMR and have an obvious potential to improve long-term competence of MVR. Therefore, they could be considered as a viable therapeutic option even in elderly patients presenting with end-stage cardiomyopathy and severe leaflet tenting.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytaa087","type":"journal-article","created":{"date-parts":[[2020,4,27]],"date-time":"2020-04-27T19:58:25Z","timestamp":1588017505000},"page":"1-5","source":"Crossref","is-referenced-by-count":4,"title":["Left ventricular reverse remodeling after successful subannular mitral valve repair in end-stage heart failure: a case report"],"prefix":"10.1093","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7418-1815","authenticated-orcid":false,"given":"Jonas","family":"Pausch","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, University Heart and Vascular Center Hamburg, Martinistra\u00dfe 52, D-20246 Hamburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatiana","family":"Sequeira Gross","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, University Heart and Vascular Center Hamburg, Martinistra\u00dfe 52, D-20246 Hamburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hermann","family":"Reichenspurner","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, University Heart and Vascular Center Hamburg, Martinistra\u00dfe 52, D-20246 Hamburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evaldas","family":"Girdauskas","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, University Heart and Vascular Center Hamburg, Martinistra\u00dfe 52, D-20246 Hamburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2020,4,27]]},"reference":[{"key":"2020062620241206200_ytaa087-B1","first-page":"26","article-title":"Mitral regurgitation\u2014unmet need for improved management strategies","volume":"5","author":"Trochu","year":"2014","journal-title":"Int J Cardiol Heart Vasc"},{"key":"2020062620241206200_ytaa087-B2","doi-asserted-by":"crossref","first-page":"e1159","DOI":"10.1161\/CIR.0000000000000503","article-title":"2017 AHA\/ACC focused update of the 2014 AHA\/ACC guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology\/American Heart Association Task Force on Clinical Practice Guidelines","volume":"135","author":"Nishimura","year":"2017","journal-title":"Circulation"},{"key":"2020062620241206200_ytaa087-B3","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1016\/j.athoracsur.2007.11.021","article-title":"Recurrence of mitral regurgitation parallels the absence of left ventricular reverse remodeling after mitral repair in advanced dilated cardiomyopathy","volume":"85","author":"De Bonis","year":"2008","journal-title":"Ann Thorac 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