{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T12:03:51Z","timestamp":1792325031731,"version":"4.4.0"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2020,7,8]],"date-time":"2020-07-08T00:00:00Z","timestamp":1594166400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Mobile valvular masses are often considered pathognomonic for infective endocarditis. We present a case of a young patient with mobile valvular masses in the context of myocarditis likely secondary to active ileal Crohn\u2019s disease. Cardiac magnetic resonance (CMR) imaging was crucial in diagnosing and monitoring our patient.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case summary<\/jats:title>\n                  <jats:p>A 27-year-old woman presented with pleuritic chest pain, dyspnoea, and a 3-day history of fevers. She also reported a 2-month history of intermittent visual loss in her right eye. She had a history of histologically proven ileal Crohn\u2019s disease, diagnosed 5\u2009months prior. She was haemodynamically unstable on presentation. Abnormalities on a transthoracic echocardiogram necessitated a transoesophageal echocardiogram. After blood cultures were sent, the patient was commenced on empirical treatment for infective endocarditis with gentamicin and flucloxacillin. Eight days after her initial presentation, all blood cultures remained negative and she was changed to empirical treatment for culture negative endocarditis with ceftriaxone and vancomycin, according to local protocol. Despite 8\u2009days of treatment for infective endocarditis she remained febrile. A CMR was organized on Day 9 and this showed myocarditis, which changed the treatment paradigm. She responded swiftly to steroids and anti-coagulation.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>In this case, echo-dense valvular lesions are not pathognomonic for infective endocarditis and a careful diagnostic process involving multi-modality imaging, including CMR, occurred to arrive at a diagnosis of myocarditis likely secondary to Crohn\u2019s disease.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytaa120","type":"journal-article","created":{"date-parts":[[2020,7,8]],"date-time":"2020-07-08T03:54:23Z","timestamp":1594180463000},"page":"1-6","source":"Crossref","is-referenced-by-count":6,"title":["Myocarditis in Crohn\u2019s disease: a case report"],"prefix":"10.1093","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6627-3739","authenticated-orcid":false,"given":"Lucy","family":"McGrath-Cadell","sequence":"first","affiliation":[{"name":"Department of Cardiology, St Vincent\u2019s Hospital, 390 Victoria Street, Darlinghurst, Sydney, 2010 NSW, Australia"},{"name":"University of New South Wales, St Vincent's Clinical School, St Vincent's Hospital Campus, Darlinghurst, Sydney, 2010 NSW, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole K","family":"Bart","sequence":"additional","affiliation":[{"name":"Department of Cardiology, St Vincent\u2019s Hospital, 390 Victoria Street, Darlinghurst, Sydney, 2010 NSW, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Cardiology, St Vincent\u2019s Hospital, 390 Victoria Street, Darlinghurst, Sydney, 2010 NSW, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2489-6430","authenticated-orcid":false,"given":"Simon","family":"Ghaly","sequence":"additional","affiliation":[{"name":"University of New South Wales, St Vincent's Clinical School, St Vincent's Hospital Campus, Darlinghurst, Sydney, 2010 NSW, Australia"},{"name":"Department of Gastroenterology, St Vincent\u2019s Hospital, 390 Victoria Street, Darlinghurst, Sydney, 2010 NSW, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cameron J","family":"Holloway","sequence":"additional","affiliation":[{"name":"Department of Cardiology, St Vincent\u2019s Hospital, 390 Victoria Street, Darlinghurst, Sydney, 2010 NSW, Australia"},{"name":"University of New South Wales, St Vincent's Clinical School, St Vincent's Hospital Campus, Darlinghurst, Sydney, 2010 NSW, Australia"},{"name":"Victor Chang Cardiac Research Institute, Lowy Packer Building, 405 Liverpool Street, Darlinghurst, Sydney, 2010 NSW, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,7,8]]},"reference":[{"key":"2020101507151532000_ytaa120-B1","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1056\/NEJMcp1206782","article-title":"Infective endocarditis","volume":"368","author":"Hoen","year":"2013","journal-title":"N Engl J Med"},{"key":"2020101507151532000_ytaa120-B2","doi-asserted-by":"crossref","first-page":"107155","DOI":"10.1016\/j.carpath.2019.107155","article-title":"Myocarditis: somethings old and something new","volume":"44","author":"Razzano","year":"2020","journal-title":"Cardiovasc Pathol"},{"key":"2020101507151532000_ytaa120-B3","doi-asserted-by":"crossref","first-page":"1877","DOI":"10.1016\/j.jacc.2017.08.044","article-title":"Cardiac Magnetic Resonance Working Group of the Italian Society of Cardiology. Cardiac MR with late gadolinium enhancement in acute myocarditis with preserved systolic function: ITAMY study","volume":"70","author":"Aquaro","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"2020101507151532000_ytaa120-B4","doi-asserted-by":"crossref","first-page":"e199","DOI":"10.1016\/j.athoracsur.2017.12.005","article-title":"Nonbacterial thrombotic endocarditis associated with Crohn disease","volume":"105","author":"Uchida","year":"2018","journal-title":"Ann Thorac Surg"},{"key":"2020101507151532000_ytaa120-B5","doi-asserted-by":"crossref","DOI":"10.33552\/OJCR.2019.01.000519","article-title":"Marantic or non-bacterial thrombotic endocarditis","volume":"1","author":"Ahluwalia","year":"2019","journal-title":"Online J Cardiovasc Res"},{"key":"2020101507151532000_ytaa120-B6","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1016\/S0140-6736(11)60648-X","article-title":"Myocarditis","volume":"379","author":"Sagar","year":"2012","journal-title":"Lancet"},{"key":"2020101507151532000_ytaa120-B7","doi-asserted-by":"crossref","first-page":"1964","DOI":"10.1016\/j.jacc.2017.08.050","article-title":"Prognostic value of cardiac magnetic resonance tissue characterization in risk stratifying patients with suspected myocarditis","volume":"70","author":"Grani","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"2020101507151532000_ytaa120-B8","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1016\/j.jacc.2009.02.007","article-title":"for the international consensus group on cardiovascular MR in myocarditis. Cardiovascular magnetic resonance in myocarditis: a JACC white paper","volume":"53","author":"Friedrich","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"2020101507151532000_ytaa120-B9","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCIMAGING.116.005242","article-title":"Detection and monitoring of acute myocarditis applying quantitative cardiovascular magnetic resonance","volume":"10","author":"Knobelsdorff-Brenkenhoff","year":"2017","journal-title":"Circ Cardiovasc Imaging"},{"key":"2020101507151532000_ytaa120-B10","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.116.003603","article-title":"Comprehensive cardiac magnetic resonance for short-term follow-up in acute myocarditis","volume":"5","author":"Luetkens","year":"2016","journal-title":"J Am Heart Assoc"}],"container-title":["European Heart Journal - Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/ehjcr\/article-pdf\/4\/4\/1\/33889800\/ytaa120.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/ehjcr\/article-pdf\/4\/4\/1\/33889800\/ytaa120.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,15]],"date-time":"2020-10-15T11:26:21Z","timestamp":1602761181000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ehjcr\/article\/4\/4\/1\/5868576"}},"subtitle":[],"editor":[{"given":"Christian Fielder","family":"Camm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"Stefan","family":"Simovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"Vishal Shahil","family":"Mehta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2020,7,8]]},"references-count":10,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2020,7,8]]},"published-print":{"date-parts":[[2020,8,1]]}},"URL":"https:\/\/doi.org\/10.1093\/ehjcr\/ytaa120","relation":{},"ISSN":["2514-2119"],"issn-type":[{"value":"2514-2119","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2020,8]]},"published":{"date-parts":[[2020,7,8]]}}}