{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T23:22:39Z","timestamp":1771456959642,"version":"3.50.1"},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2020,7,21]],"date-time":"2020-07-21T00:00:00Z","timestamp":1595289600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background\u2003<\/jats:title>\n                  <jats:p>Post-cardiac injury syndrome (PCIS) is an inflammatory process that may occur after myocardial infarction, cardiac surgery, percutaneous cardiac interventions or chest trauma. To our knowledge, PCIS following transcatheter mitral valve repair (TMVr) using the MitraClip system has not been reported.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case summary\u2003<\/jats:title>\n                  <jats:p>A 79-year-old female with chronic heart failure and severe mitral regurgitation received TMVr using the MitraClip system. After the procedure she developed elevated inflammatory markers, pericardial and pleural effusion. Cardiac magnetic resonance provided signs of pericardial and pleural inflammation. After initiating an anti-inflammatory therapy with Aspirin and Colchicine, inflammatory markers decreased markedly, pleural and pericardial effusions were regressive, and the patient showed rapid clinical improvement.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion\u2003<\/jats:title>\n                  <jats:p>Post-cardiac injury syndrome may occur after TMVr and should be considered as a differential diagnosis in patients developing chest pain, signs of pericarditis with or without pericardial effusion and elevated inflammatory markers.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytaa143","type":"journal-article","created":{"date-parts":[[2020,7,21]],"date-time":"2020-07-21T04:56:49Z","timestamp":1595307409000},"page":"1-5","source":"Crossref","is-referenced-by-count":10,"title":["Post-cardiac injury syndrome after transcatheter mitral valve repair using MitraClip system: a case report"],"prefix":"10.1093","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5883-2561","authenticated-orcid":false,"given":"Mhd Nawar","family":"Alachkar","sequence":"first","affiliation":[{"name":"Department of Cardiology, Angiology and Intensive Care, University Hospital RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Lehrke","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Angiology and Intensive Care, University Hospital RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6141-634X","authenticated-orcid":false,"given":"Nikolaus","family":"Marx","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Angiology and Intensive Care, University Hospital RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4765-109X","authenticated-orcid":false,"given":"Mohammad","family":"Almalla","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Angiology and Intensive Care, University Hospital RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2020,7,21]]},"reference":[{"key":"2020101507245955900_ytaa143-B1","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1016\/j.ijcard.2012.09.052","article-title":"Post-cardiac injury syndromes. An emerging cause of pericardial diseases","volume":"168","author":"Imazio","year":"2013","journal-title":"Int J Cardiol"},{"key":"2020101507245955900_ytaa143-B2","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1016\/j.amjcard.2011.06.025","article-title":"Contemporary features, risk factors, and prognosis of the post-pericardiotomy syndrome","volume":"108","author":"Imazio","year":"2011","journal-title":"Am J Cardiol"},{"key":"2020101507245955900_ytaa143-B3","doi-asserted-by":"crossref","first-page":"2921","DOI":"10.1093\/eurheartj\/ehv318","article-title":"2015 ESC Guidelines for the diagnosis and management of pericardial diseases: the Task Force for the Diagnosis and Management of Pericardial Diseases of the European Society of Cardiology (ESC) endorsed by: the European Association for Cardio-Thoracic Surgery (EACTS","volume":"36","author":"Adler","year":"2015","journal-title":"Eur Heart J"},{"key":"2020101507245955900_ytaa143-B4","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.1001\/jama.2015.12763","article-title":"Evaluation and treatment of pericarditis: a systematic review","volume":"314","author":"Imazio","year":"2015","journal-title":"JAMA"},{"key":"2020101507245955900_ytaa143-B5","doi-asserted-by":"crossref","first-page":"784.e1","DOI":"10.1016\/j.amjmed.2015.01.040","article-title":"Etiology of pericarditis in a prospective cohort of 1162 cases","volume":"128","author":"Gouriet","year":"2015","journal-title":"Am J Med"},{"key":"2020101507245955900_ytaa143-B6","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1186\/s12872-018-0964-4","article-title":"Post-cardiac injury syndrome in acute myocardial infarction patients undergoing PCI: a case report and literature review","volume":"18","author":"Gao","year":"2018","journal-title":"BMC Cardiovasc Disord"},{"key":"2020101507245955900_ytaa143-B7","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1007\/s00392-014-0716-0","article-title":"Post cardiac injury syndrome after initially uncomplicated CRT-D implantation: a case report and a systematic review","volume":"103","author":"Sedaghat-Hamedani","year":"2014","journal-title":"Clin Res Cardiol"},{"key":"2020101507245955900_ytaa143-B8","doi-asserted-by":"crossref","first-page":"307.e1","DOI":"10.1016\/j.repc.2013.12.005","article-title":"Post-cardiac injury syndrome following transvenous pacing: case report","volume":"33","author":"Sousa","year":"2014","journal-title":"Rev Port Cardiol"},{"key":"2020101507245955900_ytaa143-B9","first-page":"yty107","article-title":"The first post-cardiac injury syndrome reported following transcatheter aortic valve implantation: a case report","volume":"2","author":"Llubani","year":"2018","journal-title":"Eur Heart J Case Rep"},{"key":"2020101507245955900_ytaa143-B10","doi-asserted-by":"crossref","first-page":"351","DOI":"10.2459\/JCM.0b013e328353807d","article-title":"Postpericardiotomy syndrome: a proposal for diagnostic criteria","volume":"14","author":"Imazio","year":"2013","journal-title":"J Cardiovasc Med (Hagerstown)"},{"key":"2020101507245955900_ytaa143-B11","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1016\/j.jcmg.2010.04.009","article-title":"Multimodality imaging of pericardial diseases","volume":"3","author":"Yared","year":"2010","journal-title":"JACC Cardiovasc Imaging"},{"key":"2020101507245955900_ytaa143-B12","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/0002-8703(80)90618-3","article-title":"Evaluation of pericardial effusion with computed tomography","volume":"99","author":"Tomoda","year":"1980","journal-title":"Am Heart J"},{"key":"2020101507245955900_ytaa143-B13","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1093\/ehjci\/jeu128","article-title":"European Association of Cardiovascular Imaging (EACVI) position paper: multimodality imaging in pericardial disease","volume":"16","author":"Cosyns","year":"2015","journal-title":"Eur Heart J Cardiovasc Imaging"}],"container-title":["European Heart Journal - 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