{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T23:10:19Z","timestamp":1740179419490,"version":"3.37.3"},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2020,6,17]],"date-time":"2020-06-17T00:00:00Z","timestamp":1592352000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Grant-in-Aid for Scientific Research"},{"name":"JSPS KAKENHI","award":["16K09522","20K08433"],"award-info":[{"award-number":["16K09522","20K08433"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Near-infrared spectroscopy (NIRS) has been used for analysis the composition of the atherosclerotic plaque in coronary arteries. However, meaning of significant decrease in max lipid core burden index at 4\u2009mm (max LCBI4mm) during percutaneous coronary intervention (PCI) is poorly understood.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case summary<\/jats:title>\n                  <jats:p>A 64-year-old male with unstable angina underwent coronary angiography, which demonstrated a hazy tight culprit lesion in the mid-right coronary artery. Pre-intervention NIRS\u2013intravascular ultrasound (NIRS\u2013IVUS) and chemogram showed plaque with high lipid burden at the culprit lesion. Then, we used a distal protection device before PCI because of high max LCBI4mm in the lesion. After pre-dilation with a scoring balloon, repeat NIRS\u2013IVUS interrogation revealed an almost complete disappearance of the yellow signal and decrease in max LCBI4mm (from 537 to 44) significantly, suggesting decrease in the lipid content of the plaque. Finally, a drug-eluting stent deployment followed by inflation of a non-compliant balloon led to an excellent result. After PCI, we detected trapped large amounts of debris on retrieval of the filter. Pathological diagnosis confirmed that trapped material was lipid-rich plaque including cholesterol crystals.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>This is the first report directly demonstrated that significant decrease in max LCBI4mm at culprit lesion should be associated with the leakage of cholesterol crystals from lipid-rich plaque during PCI in the clinical patient.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytaa148","type":"journal-article","created":{"date-parts":[[2020,6,17]],"date-time":"2020-06-17T04:23:46Z","timestamp":1592367826000},"page":"1-5","source":"Crossref","is-referenced-by-count":1,"title":["Significant decrease in lipid core burden index following balloon dilation was associated with the leakage of cholesterol crystals in a patient: a case report"],"prefix":"10.1093","volume":"4","author":[{"given":"Soshi","family":"Moriya","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Medicine, Juntendo University, 2-1-1, Hongo, Bunkyo-ku, 113-8421 Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8878-9792","authenticated-orcid":false,"given":"Kikuo","family":"Isoda","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Juntendo University, 2-1-1, Hongo, Bunkyo-ku, 113-8421 Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomotaka","family":"Dohi","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Juntendo University, 2-1-1, Hongo, Bunkyo-ku, 113-8421 Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinya","family":"Okazaki","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Juntendo University, 2-1-1, Hongo, Bunkyo-ku, 113-8421 Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2020,6,17]]},"reference":[{"key":"2020101507244280800_ytaa148-B1","doi-asserted-by":"crossref","first-page":"1738","DOI":"10.1016\/S0735-1097(02)01877-6","article-title":"Prognostic significance of elevated troponin I after percutaneous coronary intervention","volume":"39","author":"Cantor","year":"2002","journal-title":"J Am Coll Cardiol"},{"key":"2020101507244280800_ytaa148-B2","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1016\/S0195-668X(03)00258-6","article-title":"Role of cardiac troponin T in the long-term risk stratification of patients undergoing percutaneous coronary intervention","volume":"24","author":"Kizer","year":"2003","journal-title":"Eur Heart J"},{"key":"2020101507244280800_ytaa148-B3","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/S0167-5273(03)00105-0","article-title":"Cardiac troponin T and I and creatine kinase-MB as markers of myocardial injury and predictors of outcome following percutaneous coronary intervention","volume":"92","author":"Nageh","year":"2003","journal-title":"Int J Cardiol"},{"key":"2020101507244280800_ytaa148-B4","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1161\/CIRCIMAGING.113.000448","article-title":"Intracoronary and noninvasive imaging for prediction of distal embolization and periprocedural myocardial infarction during native coronary artery percutaneous intervention","volume":"6","author":"Patel","year":"2013","journal-title":"Circ Cardiovasc Imaging"},{"key":"2020101507244280800_ytaa148-B5","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.carrev.2015.06.001","article-title":"Role of near-infrared spectroscopy in intravascular coronary imaging","volume":"16","author":"Negi","year":"2015","journal-title":"Cardiovasc Revasc Med"},{"key":"2020101507244280800_ytaa148-B6","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.5114\/aoms.2016.62904","article-title":"The role of near-infrared spectroscopy in the detection of vulnerable atherosclerotic plaques","volume":"6","author":"Horvath","year":"2016","journal-title":"Arch Med Sci"},{"key":"2020101507244280800_ytaa148-B7","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1002\/ccd.22164","article-title":"Current status of vulnerable plaque detection","volume":"75","author":"Sharif","year":"2009","journal-title":"Cathet Cardiovasc Intervent"},{"key":"2020101507244280800_ytaa148-B8","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1007\/s11883-012-0304-6","article-title":"Imaging of vulnerable plaques using near-infrared spectroscopy for risk stratification of atherosclerosis","volume":"15","author":"Sanon","year":"2013","journal-title":"Curr Atheroscler Rep"},{"key":"2020101507244280800_ytaa148-B9","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.jacc.2009.10.090","article-title":"First-in-man clinical use of combined near-infrared spectroscopy and intravascular ultrasound: a potential key to predict distal embolization and no-reflow?","volume":"56","author":"Schultz","year":"2010","journal-title":"J Am Coll Cardiol"},{"key":"2020101507244280800_ytaa148-B10","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1002\/ccd.23358","article-title":"Multimodality direct coronary imaging with combined near-infrared spectroscopy and intravascular ultrasound: initial US experience","volume":"81","author":"Madder","year":"2013","journal-title":"Cathet Cardiovasc Intervent"},{"key":"2020101507244280800_ytaa148-B11","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1161\/CIRCINTERVENTIONS.111.963264","article-title":"Detection of lipid-core plaques by intracoronary near-infrared spectroscopy identifies high risk of periprocedural myocardial infarction","volume":"4","author":"Goldstein","year":"2011","journal-title":"Circ Cardiovasc Interv"},{"key":"2020101507244280800_ytaa148-B12","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.1016\/j.jcmg.2009.10.003","article-title":"Coronary embolization following balloon dilation of lipid-core plaques","volume":"2","author":"Goldstein","year":"2009","journal-title":"JACC Cardiovasc Imaging"}],"container-title":["European Heart Journal - Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/ehjcr\/article-pdf\/4\/4\/1\/33889441\/ytaa148.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/ehjcr\/article-pdf\/4\/4\/1\/33889441\/ytaa148.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,15]],"date-time":"2020-10-15T11:33:04Z","timestamp":1602761584000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ehjcr\/article\/4\/4\/1\/5858283"}},"subtitle":[],"editor":[{"given":"Riccardo","family":"Liga","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Romain","family":"Didier","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Andre","family":"Dias","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Christian Fielder","family":"Camm","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Peregrine","family":"Green","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Juntendo University, 2-1-1, Hongo, Bunkyo-ku, 113-8421 Tokyo, Japan"}],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2020,6,17]]},"references-count":12,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2020,6,17]]},"published-print":{"date-parts":[[2020,8,1]]}},"URL":"https:\/\/doi.org\/10.1093\/ehjcr\/ytaa148","relation":{},"ISSN":["2514-2119"],"issn-type":[{"type":"electronic","value":"2514-2119"}],"subject":[],"published-other":{"date-parts":[[2020,8]]},"published":{"date-parts":[[2020,6,17]]}}}