{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T20:17:09Z","timestamp":1767212229375,"version":"3.37.3"},"reference-count":7,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2020,8,24]],"date-time":"2020-08-24T00:00:00Z","timestamp":1598227200000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Primary cardiac lymphoma is an extra-nodal non-Hodgkin\u2019s lymphoma, which usually responds well to chemotherapy. The disease has high mortality rate unless it is recognized and treated in time. Tissue pathology is crucially the diagnosis gold standard for treatment plan. This is a case report of an elderly female who presented with a huge right-sided cardiac tumour obstructing tricuspid flow.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case summary<\/jats:title>\n                  <jats:p>An 81-year-old Asian female presented with clinical right-sided heart failure. Echocardiogram showed a large mass compressing and obliterating the right atrium. Trans-jugular tissue biopsy was performed. Initial pathology report was consistent with an angiosarcoma, based on an expression of Fli-1 (Friend leukaemia virus integration 1) from immunohistochemical staining. She died shortly after refusal to surgery. Autopsy was performed with diagnosis change to a diffuse large B-cell lymphoma (DLBCL) after tissue pathology.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>Primary cardiac lymphoma is extremely rare. Adequate tissue and proper immunohistochemical staining are mandatory for treatment plan. Besides an angiosarcoma, DLBCL should be considered in the differential diagnosis of Fli-1 positive tissue cardiac mass.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytaa160","type":"journal-article","created":{"date-parts":[[2020,8,23]],"date-time":"2020-08-23T23:57:37Z","timestamp":1598227057000},"page":"1-5","source":"Crossref","is-referenced-by-count":2,"title":["Diagnostic challenge in primary cardiac lymphoma: a case report"],"prefix":"10.1093","volume":"4","author":[{"given":"Chonthicha","family":"Tanking","sequence":"first","affiliation":[{"name":"Chulabhorn Hospital, 906 Kamphaeng Phet 6 Rd, Talat Bang Khen, Lak Si, Bangkok 10210, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9153-8441","authenticated-orcid":false,"given":"Supawat","family":"Ratanapo","sequence":"additional","affiliation":[{"name":"Phramongklutklao College of Medicine & Phramongklutklao Hospital, 315 Ratchawithi Rd, Thung Phaya Thai, Ratchathewi, Bangkok 10400, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2020,8,23]]},"reference":[{"key":"2020110901530211700_ytaa160-B1","doi-asserted-by":"crossref","first-page":"2707","DOI":"10.1245\/s10434-012-2334-2","article-title":"Cardiac angiosarcoma management and outcome: 20-years single-institution experience","volume":"19","author":"Look Hong","year":"2012","journal-title":"Ann Surg Oncol"},{"key":"2020110901530211700_ytaa160-B2","first-page":"1027","article-title":"Tumors of the heart. A 20-year experience with a review of 12,485 consecutive autopsies","volume":"117","author":"Lam","year":"1993","journal-title":"Arch Pathol Lab Med"},{"key":"2020110901530211700_ytaa160-B3","doi-asserted-by":"crossref","first-page":"103","DOI":"10.12659\/MSM.889875","article-title":"Primary cardiac angiosarcoma\u2014a review","volume":"20","author":"Patel","year":"2014","journal-title":"Med Sci Monit"},{"key":"2020110901530211700_ytaa160-B4","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1369\/jhc.4A6514.2005","article-title":"Immunohistochemical expression of endothelial markers CD31, CD34, von Willebrand factor, and Fli-1 in normal human tissues","volume":"54","author":"Pusztaszeri","year":"2006","journal-title":"J Histochem Cytochem"},{"key":"2020110901530211700_ytaa160-B5","first-page":"52","article-title":"Frequent CD99 and Fli-1 expression in diffuse large B-cell lymphoma and their association with proliferative and apoptotic rates","volume":"9","author":"Berber","year":"2013","journal-title":"Nobel Med"},{"key":"2020110901530211700_ytaa160-B6","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1002\/hon.2301","article-title":"Primary cardiac lymphoma: diagnosis, treatment and outcome in a modern series","volume":"35","author":"Carras","year":"2017","journal-title":"Hematol Oncol"},{"key":"2020110901530211700_ytaa160-B7","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/j.ijcard.2010.02.016","article-title":"Primary cardiac lymphoma","volume":"149","author":"Miguel","year":"2011","journal-title":"Int J Cardiol"}],"container-title":["European Heart Journal - Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/ehjcr\/article-pdf\/4\/5\/1\/34168302\/ytaa160.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/ehjcr\/article-pdf\/4\/5\/1\/34168302\/ytaa160.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,9]],"date-time":"2020-11-09T06:53:17Z","timestamp":1604904797000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ehjcr\/article\/4\/5\/1\/5896163"}},"subtitle":[],"editor":[{"given":"Alberto","family":"Bouzas-Mosquera","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Giampiero","family":"Vizzari","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Peysh A","family":"Patel","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Rami Riziq Yousef","family":"Abumuaileq","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Mohammed Majid","family":"Akhtar","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2020,8,23]]},"references-count":7,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2020,8,23]]},"published-print":{"date-parts":[[2020,10,1]]}},"URL":"https:\/\/doi.org\/10.1093\/ehjcr\/ytaa160","relation":{},"ISSN":["2514-2119"],"issn-type":[{"type":"electronic","value":"2514-2119"}],"subject":[],"published-other":{"date-parts":[[2020,10]]},"published":{"date-parts":[[2020,8,23]]}}}