{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T23:10:26Z","timestamp":1740179426112,"version":"3.37.3"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Although left bundle branch area pacing (LBBAP) can capture the His-Purkinje conduction system and create a narrower paced QRS duration, its mechanism has not been investigated. In this case report, ventricular activation patterns were evaluated using three-dimensional electroanatomical mapping during LBBAP and right ventricular septal pacing (RVSP).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case summary<\/jats:title>\n                  <jats:p>An 81-year-old woman with sick sinus syndrome received LBBAP, followed 4\u2009months later with atrial fibrillation ablation. We compared ventricular activation patterns during RVSP and LBBAP using a three-dimensional electro-anatomical mapping system. Paced QRS durations during RVSP and LBBAP were 163 ms and 115 ms, respectively. The activation pattern and the total left ventricular (LV) activation time were similar during RVSP and LBBAP (86 and 73 ms, respectively), despite the conduction system capture during LBBAP. The stimulus interval to the latest LV activation point during RVSP was 117 ms, and transseptal conduction time was 31 ms (117\u2009\u2212\u200986 ms).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>Although LBBAP could capture the His-Purkinje conduction system, neither ventricular activation patterns nor total activation time changed dramatically. The mechanism of narrower paced QRS duration during LBBAP compared to that during RVSP can be attributable to passing over the slow transseptal conduction.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytaa239","type":"journal-article","created":{"date-parts":[[2020,8,13]],"date-time":"2020-08-13T07:07:29Z","timestamp":1597302449000},"page":"1-5","source":"Crossref","is-referenced-by-count":4,"title":["What is the mechanism of narrow paced QRS duration during left bundle branch area pacing? A case report"],"prefix":"10.1093","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3822-829X","authenticated-orcid":false,"given":"Yusuke","family":"Hayashi","sequence":"first","affiliation":[{"name":"Department of Cardiology, Osaka City General Hospital, 2-13-22 Miyakojima-hondori, Miyakojima-ku, Osaka 534-0021, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9330-899X","authenticated-orcid":false,"given":"Kenji","family":"Shimeno","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Osaka City General Hospital, 2-13-22 Miyakojima-hondori, Miyakojima-ku, Osaka 534-0021, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenichi","family":"Nakatsuji","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Osaka City General Hospital, 2-13-22 Miyakojima-hondori, Miyakojima-ku, Osaka 534-0021, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takahiko","family":"Naruko","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Osaka City General Hospital, 2-13-22 Miyakojima-hondori, Miyakojima-ku, Osaka 534-0021, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2020,8,12]]},"reference":[{"key":"2020101507350884300_ytaa239-B1","doi-asserted-by":"crossref","first-page":"2932","DOI":"10.1161\/01.CIR.0000072769.17295.B1","article-title":"Adverse effect of ventricular pacing on heart failure and atrial fibrillation among patients with normal baseline QRS duration in a clinical trial of pacemaker therapy for sinus node dysfunction","volume":"107","author":"Sweeney","year":"2003","journal-title":"Circulation"},{"key":"2020101507350884300_ytaa239-B2","doi-asserted-by":"crossref","first-page":"3115","DOI":"10.1001\/jama.288.24.3115","article-title":"Dual-chamber pacing or ventricular backup pacing in patients with an implantable defibrillator: the dual chamber and VVI implantable defibrillator (DAVID) trial","volume":"288","author":"Wilkoff","year":"2002","journal-title":"JAMA"},{"key":"2020101507350884300_ytaa239-B3","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1016\/j.hrthm.2017.12.022","article-title":"Permanent His-bundle pacing: long-term lead performance and clinical outcomes","volume":"15","author":"Vijayaraman","year":"2018","journal-title":"Heart Rhythm"},{"key":"2020101507350884300_ytaa239-B4","first-page":"1766","article-title":"Permanent left bundle branch area pacing for atrioventricular block: feasibility, safety, and acute effect","volume":"16","author":"Li","year":"2019","journal-title":"Heart Rhyhtm"},{"key":"2020101507350884300_ytaa239-B5","first-page":"1774","article-title":"Prospective evaluation of feasibility, electrophysiologic and echocardiographic characteristics of left bundle branch area pacing","volume":"16","author":"Vijayaraman","year":"2019","journal-title":"Heart Rhyhtm"},{"key":"2020101507350884300_ytaa239-B6","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.1016\/j.hrthm.2019.06.016","article-title":"A beginner's guide to permanent left bundle branch pacing","volume":"16","author":"Huang","year":"2019","journal-title":"Heart Rhythm"},{"key":"2020101507350884300_ytaa239-B7","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1007\/s10840-013-9858-7","article-title":"The infrahisian conduction system and endocavitary cardiac structures: relevance for the invasive electrophysiologist","volume":"39","author":"Syed","year":"2014","journal-title":"J Interv Card Electrophysiol"},{"key":"2020101507350884300_ytaa239-B8","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.jelectrocard.2017.03.004","article-title":"The normal variants in the left bundle branch system","volume":"50","author":"Elizari","year":"2017","journal-title":"J Electrocardiol"},{"key":"2020101507350884300_ytaa239-B9","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1161\/CIRCEP.111.000028","article-title":"Transeptal conduction as an important determinant for cardiac resynchronization therapy, as revealed by extensive electrical mapping in the dyssynchronous canine heart","volume":"6","author":"Strik","year":"2013","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"2020101507350884300_ytaa239-B10","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1161\/01.RES.0000199396.30688.eb","article-title":"Evidence of structural remodeling in the dyssynchronous failing heart","volume":"98","author":"Helm","year":"2006","journal-title":"Circ Res"}],"container-title":["European Heart Journal - Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/ehjcr\/article-pdf\/4\/4\/1\/33889735\/ytaa239.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/ehjcr\/article-pdf\/4\/4\/1\/33889735\/ytaa239.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,15]],"date-time":"2020-10-15T11:41:55Z","timestamp":1602762115000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ehjcr\/article\/4\/4\/1\/5891812"}},"subtitle":[],"editor":[{"given":"Benedict","family":"Glover","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Konstantinos","family":"Iliodromitis","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Habib","family":"Khan","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Peter Henry","family":"Waddingham","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Amir","family":"Aziz","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Peysh A","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Osaka City General Hospital, 2-13-22 Miyakojima-hondori, Miyakojima-ku, Osaka 534-0021, Japan"}],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2020,8,1]]},"references-count":10,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2020,8,12]]},"published-print":{"date-parts":[[2020,8,1]]}},"URL":"https:\/\/doi.org\/10.1093\/ehjcr\/ytaa239","relation":{},"ISSN":["2514-2119"],"issn-type":[{"type":"electronic","value":"2514-2119"}],"subject":[],"published-other":{"date-parts":[[2020,8]]},"published":{"date-parts":[[2020,8,1]]}}}