{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T12:35:44Z","timestamp":1779194144060,"version":"3.51.4"},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2020,9,24]],"date-time":"2020-09-24T00:00:00Z","timestamp":1600905600000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Hypertrophic cardiomyopathy (HCM) is a genetically determined myocardial disease that constitutes the main cause of sudden cardiac death (SCD) in young athletes. Apical HCM (ApHCM) represents a complex subset of patients, whose risk of SCD seems not negligible. Most applied scores likely underestimate the risk of heart events in this subset of patients.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case summary<\/jats:title>\n                  <jats:p>We report the case of a 55-year-old man who was admitted in the emergency department after an episode of aborted sudden death due to ventricular fibrillation. The electrocardiogram made at admission was noted for atrial fibrillation and a new-onset left bundle branch block. Emergency coronary angiography was normal. The electrocardiogram was repeated and showed symmetrical and profound inversion of T waves in the lateral leads. Transthoracic echocardiogram and cardiac magnetic resonance revealed left ventricular apical hypertrophy suggestive of apical variant of HCM. A cardiac defibrillator was implanted for secondary prevention of SCD. After 6 months of follow-up no further rhythmic events were noted.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>Although low, the risk of SCD of ApHCM patients is not negligible. This case illustrates the need for searching of new predictors of rhythmic risk in patients with ApHCM.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytaa316","type":"journal-article","created":{"date-parts":[[2020,9,24]],"date-time":"2020-09-24T02:26:46Z","timestamp":1600914406000},"page":"1-4","source":"Crossref","is-referenced-by-count":5,"title":["Apical hypertrophic cardiomyopathy, are low-risk patients really at low risk? A case report"],"prefix":"10.1093","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4176-5814","authenticated-orcid":false,"given":"Rui","family":"Files Flores","sequence":"first","affiliation":[{"name":"Cardiology Department, Hospital of Braga, Sete Fontes\u2014S\u00e3o Victor, 4710-243 Braga, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2722-8596","authenticated-orcid":false,"given":"Fernando","family":"Man\u00e9","sequence":"additional","affiliation":[{"name":"Cardiology Department, Hospital of Braga, Sete Fontes\u2014S\u00e3o Victor, 4710-243 Braga, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nuno","family":"Antunes","sequence":"additional","affiliation":[{"name":"Cardiology Department, Hospital of Braga, Sete Fontes\u2014S\u00e3o Victor, 4710-243 Braga, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9314-0453","authenticated-orcid":false,"given":"V\u00edtor Hugo","family":"Pereira","sequence":"additional","affiliation":[{"name":"Cardiology Department, Hospital of Braga, Sete Fontes\u2014S\u00e3o Victor, 4710-243 Braga, Portugal"},{"name":"Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal"},{"name":"ICVS\/3B\u2019s-PT Government Associate Laboratory, Campus de Gualtar, 4710-057 Braga\/Guimar\u00e3es, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2020,9,23]]},"reference":[{"key":"2020110901534651600_ytaa316-B1","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1056\/NEJMra1710575","article-title":"Clinical course and management of hypertrophic 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(Lond)"},{"key":"2020110901534651600_ytaa316-B5","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1007\/s11239-019-02026-1","article-title":"Tissue-level inflammation and ventricular remodeling in hypertrophic cardiomyopathy","volume":"49","author":"Becker","year":"2020","journal-title":"J Thromb Thrombolysis"},{"key":"2020110901534651600_ytaa316-B6","doi-asserted-by":"crossref","first-page":"S25","DOI":"10.1017\/S1047951116002195","article-title":"Hypertrophic cardiomyopathy","volume":"27","author":"Shah","year":"2017","journal-title":"Cardiol Young"},{"key":"2020110901534651600_ytaa316-B7","doi-asserted-by":"crossref","first-page":"e276","DOI":"10.1097\/MJT.0000000000000107","article-title":"Sudden cardiac arrest in a patient with apical hypertrophic cardiomyopathy: case report and a brief review of literature","volume":"23","author":"Gupta","year":"2016","journal-title":"Am J 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cardiomyopathy\u2014a tertiary centre mri registry","volume":"103","author":"Khan","year":"2017","journal-title":"Heart"},{"key":"2020110901534651600_ytaa316-B12","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.hlc.2018.07.019","article-title":"Sudden cardiac death and ventricular arrhythmias in hypertrophic cardiomyopathy","volume":"28","author":"Moore","year":"2019","journal-title":"Heart Lung Circ"}],"container-title":["European Heart Journal - Case 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