{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T23:10:45Z","timestamp":1740179445903,"version":"3.37.3"},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2020,11,22]],"date-time":"2020-11-22T00:00:00Z","timestamp":1606003200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["2018R1D1A1A09083902"],"award-info":[{"award-number":["2018R1D1A1A09083902"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Ventricular arrhythmia and sudden cardiac arrest caused by multivessel coronary artery spasm (CAS) is rare. Although coronary angiography (CAG) with provocation testing is the diagnostic gold standard in current vasospastic angina guidelines, it can cause severe procedure-related complications. Here, we report a novel technique involving dual-acquisition coronary computed tomography angiography (CCTA) to detect multivessel CAS in a patient who survived out-of-hospital cardiac arrest (OHCA).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case summary<\/jats:title>\n                  <jats:p>A 58-year-old healthy Korean male survived OHCA caused by ventricular fibrillation (VF), experiencing seven episodes of defibrillation and cardiopulmonary resuscitation, and was referred to the Emergency Room. Vital signs were stable and physical examination, electrocardiogram, chest, and brain CT did not show any abnormal findings, except elevated hs-Troponin I levels (0.1146\u2009ng\/mL). Echocardiogram revealed a regional wall motion abnormality in the inferior wall, with a low normal left ventricular ejection fraction (50%). A multivessel CAS (both left and right) was detected using a dual-acquisition CCTA technique (presence and absence of intravenous nitrate). During CAG with the 2nd injection of ergonovine, a prolonged and refractory total occlusion in the proximal-ostial right coronary artery was completely relieved after a seven-cycle intracoronary injection regimen of nitroglycerine. The patient was discharged with the recommendation of smoking and alcohol cessation. Nitrate and calcium channel blockers were also prescribed. The patient had no further events at 3\u2009months of follow-up after discharge.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>Dual-acquisition CCTA is a promising tool to detect multivessel CAS.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytaa369","type":"journal-article","created":{"date-parts":[[2020,11,22]],"date-time":"2020-11-22T09:26:40Z","timestamp":1606037200000},"page":"1-5","source":"Crossref","is-referenced-by-count":1,"title":["Severe multivessel coronary artery spasm detected by computed tomography: a case report"],"prefix":"10.1093","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2043-1978","authenticated-orcid":false,"given":"Cai De","family":"Jin","sequence":"first","affiliation":[{"name":"Department of Cardiology, Dong-A University Hospital, 26 Daesingongwon-ro, Seo-gu, Busan\u00a049201, Republic of Korea"},{"name":"Department of Cardiology, Affiliated Hospital of Zunyi Medical University, Zunyi 563003, Guizhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3468-6453","authenticated-orcid":false,"given":"Moo Hyun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Dong-A University Hospital, 26 Daesingongwon-ro, Seo-gu, Busan\u00a049201, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Su-A","family":"Jo","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Dong-A University Hospital, 26 Daesingongwon-ro, Seo-gu, Busan\u00a049201, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7262-1848","authenticated-orcid":false,"given":"Kyunghee","family":"Lim","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Dong-A University Hospital, 26 Daesingongwon-ro, Seo-gu, Busan\u00a049201, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2020,11,22]]},"reference":[{"key":"2021010812222096100_ytaa369-B1","first-page":"83","article-title":"Sudden cardiac death secondary to severe multivessel coronary spasm","volume":"149","author":"Sanchez-Somonte","year":"2017","journal-title":"Med Clin (Barc)"},{"key":"2021010812222096100_ytaa369-B2","doi-asserted-by":"crossref","first-page":"296","DOI":"10.5001\/omj.2014.77","article-title":"Malignant multivessel coronary spasm complicated by myocardial infarction, transient complete heart block, ventricular fibrillation, cardiogenic shock and ischemic stroke","volume":"29","author":"Thomson","year":"2014","journal-title":"Oman Med J"},{"key":"2021010812222096100_ytaa369-B3","doi-asserted-by":"crossref","first-page":"2779","DOI":"10.1253\/circj.CJ-66-0098","article-title":"Guidelines for diagnosis and treatment of patients with vasospastic angina (Coronary Spastic Angina) (JCS 2013)","volume":"78","year":"2014","journal-title":"Circ J"},{"key":"2021010812222096100_ytaa369-B4","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1093\/eurheartj\/ehs199","article-title":"Clinical implications of provocation tests for coronary artery spasm: safety, arrhythmic complications, and prognostic impact: multicentre registry study of the Japanese Coronary Spasm Association","volume":"34","author":"Takagi","year":"2013","journal-title":"Eur Heart J"},{"key":"2021010812222096100_ytaa369-B5","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1007\/s00330-016-4476-2","article-title":"Noninvasive detection of coronary vasospastic angina using a double-acquisition coronary CT angiography protocol in the presence and absence of an intravenous nitrate: a pilot study","volume":"27","author":"Kang","year":"2017","journal-title":"Eur Radiol"},{"key":"2021010812222096100_ytaa369-B6","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1159\/000478926","article-title":"Assessing vessel tone during coronary artery spasm by dual-acquisition multidetector computed tomography angiography","volume":"139","author":"Jin","year":"2018","journal-title":"Cardiology"},{"key":"2021010812222096100_ytaa369-B7","doi-asserted-by":"crossref","first-page":"e91","DOI":"10.1016\/j.jacc.2017.10.054","article-title":"2017 AHA\/ACC\/HRS guideline for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: a report of the American College of Cardiology\/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society","volume":"72","author":"Al-Khatib","year":"2018","journal-title":"J Am Coll Cardiol"},{"key":"2021010812222096100_ytaa369-B8","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.ijcard.2011.05.055","article-title":"Sudden cardiac arrest and syncope triggered by coronary spasm","volume":"163","author":"Togashi","year":"2013","journal-title":"Int J Cardiol"},{"key":"2021010812222096100_ytaa369-B9","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1253\/circj.CJ-12-0846","article-title":"Characteristics of patients with cardiac arrest caused by coronary vasospasm","volume":"77","author":"Kobayashi","year":"2013","journal-title":"Circ J"},{"key":"2021010812222096100_ytaa369-B10","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1016\/j.ijcard.2013.12.284","article-title":"Predictors of recurrent sudden cardiac death in patients associated with coronary vasospasm","volume":"172","author":"Lee","year":"2014","journal-title":"Int J Cardiol"},{"key":"2021010812222096100_ytaa369-B11","doi-asserted-by":"crossref","first-page":"53","DOI":"10.2183\/pjab.95.005","article-title":"Coronary artery spasm - clinical features, pathogenesis and treatment","volume":"95","author":"Yasue","year":"2019","journal-title":"Proc Jpn Acad Ser B"},{"key":"2021010812222096100_ytaa369-B12","doi-asserted-by":"crossref","first-page":"1144","DOI":"10.1016\/j.jacc.2013.07.018","article-title":"Prognostic stratification of patients with vasospastic angina: a comprehensive clinical risk score developed by the Japanese Coronary Spasm Association","volume":"62","author":"Takagi","year":"2013","journal-title":"J Am Coll Cardiol"},{"key":"2021010812222096100_ytaa369-B13","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.jacc.2016.04.050","article-title":"Prognosis of variant angina manifesting as aborted sudden cardiac death","volume":"68","author":"Ahn","year":"2016","journal-title":"J Am Coll Cardiol"},{"key":"2021010812222096100_ytaa369-B14","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1016\/j.jacc.2012.03.070","article-title":"Clinical implications of an implantable cardioverter-defibrillator in patients with vasospastic angina and lethal ventricular arrhythmia","volume":"60","author":"Matsue","year":"2012","journal-title":"J Am Coll Cardiol"}],"container-title":["European Heart Journal - Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/ehjcr\/article-pdf\/4\/6\/1\/35545027\/ytaa369.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/ehjcr\/article-pdf\/4\/6\/1\/35545027\/ytaa369.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,13]],"date-time":"2021-01-13T23:55:07Z","timestamp":1610582107000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ehjcr\/article\/4\/6\/1\/5998319"}},"subtitle":[],"editor":[{"given":"Akodad","family":"Mariama","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Wood","family":"Alice","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Asher","family":"Elad","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Simovic","family":"Stefan","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Patel","family":"Peysh A","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2020,11,22]]},"references-count":14,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2020,11,22]]},"published-print":{"date-parts":[[2020,12,1]]}},"URL":"https:\/\/doi.org\/10.1093\/ehjcr\/ytaa369","relation":{},"ISSN":["2514-2119"],"issn-type":[{"type":"electronic","value":"2514-2119"}],"subject":[],"published-other":{"date-parts":[[2020,12]]},"published":{"date-parts":[[2020,11,22]]}}}