{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T09:05:45Z","timestamp":1771232745373,"version":"3.50.1"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2021,2,16]],"date-time":"2021-02-16T00:00:00Z","timestamp":1613433600000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,2,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background\u2003<\/jats:title>\n                  <jats:p>Post-myocardial infarction ventricular septal defects (VSDs) have become rare in the reperfusion era but remain associated with very high morbidity and mortality. As patients defer prompt evaluation and management of acute coronary syndromes during the COVID-19 global pandemic, the incidence of these and other post-infarction mechanical complications is expected to increase.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case summary\u2003<\/jats:title>\n                  <jats:p>A 37-year-old gentleman with multiple coronary artery disease risk factors presented with intermittent chest discomfort and 1\u2009week of heart failure symptoms. An echocardiogram demonstrated a large muscular VSD and coronary angiography confirmed the presence of an anterior wall infarction. He was subsequently referred for transcatheter VSD repair and showed rapid clinical improvement in his symptoms.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion\u2003<\/jats:title>\n                  <jats:p>Post-infarction VSDs remain associated with a high degree of morbidity and mortality. Surgical repair of acutely ruptured myocardium can be technically challenging, and transcatheter repair has emerged as a safe and effective alternative.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytab027","type":"journal-article","created":{"date-parts":[[2021,2,19]],"date-time":"2021-02-19T06:42:46Z","timestamp":1613716966000},"source":"Crossref","is-referenced-by-count":7,"title":["Ventricular septal defect complicating delayed presentation of acute myocardial infarction during COVID-19 lockdown: a case report"],"prefix":"10.1093","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9386-4032","authenticated-orcid":false,"given":"Matthew C","family":"Evans","sequence":"first","affiliation":[{"name":"Division of Cardiology, Medical University of South Carolina, 30 Courtenay Drive, 326\/MSC 592, Charleston, SC 29425, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel H","family":"Steinberg","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Medical University of South Carolina, 30 Courtenay Drive, 326\/MSC 592, Charleston, SC 29425, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2928-6316","authenticated-orcid":false,"given":"John F","family":"Rhodes","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Medical University of South Carolina, 30 Courtenay Drive, 326\/MSC 592, Charleston, SC 29425, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9045-7722","authenticated-orcid":false,"given":"Ryan J","family":"Tedford","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Medical University of South Carolina, 30 Courtenay Drive, 326\/MSC 592, Charleston, SC 29425, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,2,16]]},"reference":[{"key":"2021021616382267000_ytab027-B1","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1161\/01.CIR.101.1.27","article-title":"Risk factors, angiographic patterns, and outcomes in patients with ventricular septal defect complicating acute myocardial infarction. GUSTO-I (Global Utilization of Streptokinase and TPA for Occluded Coronary Arteries) Trial Investigators","volume":"101","author":"Crenshaw","year":"2000","journal-title":"Circulation"},{"key":"2021021616382267000_ytab027-B2","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1111\/joic.12556","article-title":"Management of post-myocardial infarction ventricular septal defects: a critical assessment","volume":"31","author":"Omar","year":"2018","journal-title":"J Interven Cardiol"},{"key":"2021021616382267000_ytab027-B3","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1016\/S0735-1097(00)00878-0","article-title":"Outcome and profile of ventricular septal rupture with cardiogenic shock after myocardial infarction: a report from the SHOCK Trial Registry. 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Improved early results combined with analysis of late functional status","volume":"99","author":"Skillington","year":"1990","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2021021616382267000_ytab027-B10","article-title":"Impact of coronavirus disease 2019 (COVID-19) outbreak on outcome of myocardial infarction in Hong Kong, China. 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