{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T23:41:37Z","timestamp":1767829297343,"version":"3.49.0"},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2021,2,16]],"date-time":"2021-02-16T00:00:00Z","timestamp":1613433600000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,2,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>SARS-CoV2, also known as COVID-19, is a specific strain of coronavirus that is responsible for an ongoing global pandemic. COVID-19 primarily targets the respiratory system via droplet transmission, causing symptoms similar to influenza, including fever, cough, and shortness of breath. It is now known to impact other organ systems, causing significant cardiovascular and gastrointestinal illness, among others.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case summary<\/jats:title>\n                  <jats:p>We describe two cases of COVID-19 induced myocarditis presenting with cardiogenic shock. These cases highlight the importance of understanding the lethal cardiac complications of COVID-19 infection, as well as its presentation, diagnosis, pathophysiology, and potential treatment options. These two cases involve patients without underlying cardiovascular disease risk factors who experienced prolonged symptoms of COVID-19 infection. Both patients presented with cardiogenic shock more than one week after symptom onset and diagnosis. These cases demonstrate the late presentation of myocarditis and cardiogenic shock, treated with corticosteroids and inotropes, with subsequent recovery of cardiac function.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>The cases highlight the importance of recognizing late presentation viral myocarditis secondary to COVID-19 infection, even in patients without underlying cardiac disease.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytab028","type":"journal-article","created":{"date-parts":[[2021,2,19]],"date-time":"2021-02-19T06:32:18Z","timestamp":1613716338000},"source":"Crossref","is-referenced-by-count":10,"title":["Myocarditis in COVID-19 presenting with cardiogenic shock: a case series"],"prefix":"10.1093","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7319-5668","authenticated-orcid":false,"given":"Adam","family":"Purdy","sequence":"first","affiliation":[{"name":"Department of Pulmonary & Critical Care, St. Luke's University Health Network, 709 Delaware Avenue, Bethlehem, PA 18015, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Firas","family":"Ido","sequence":"additional","affiliation":[{"name":"Department of Pulmonary & Critical Care, St. Luke's University Health Network, 709 Delaware Avenue, Bethlehem, PA 18015, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stacie","family":"Sterner","sequence":"additional","affiliation":[{"name":"Department of Pulmonary & Critical Care, St. Luke's University Health Network, 709 Delaware Avenue, Bethlehem, PA 18015, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7950-6159","authenticated-orcid":false,"given":"Eric","family":"Tesoriero","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology & Critical Care, St. Luke's University Health Network, 709 Delaware Avenue, Bethlehem, PA 18015, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tokunbo","family":"Matthews","sequence":"additional","affiliation":[{"name":"Department of Pulmonary & Critical Care, St. Luke's University Health Network, 709 Delaware Avenue, Bethlehem, PA 18015, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9051-5435","authenticated-orcid":false,"given":"Abhishek","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Heart Failure, and Transplantation Cardiology, Atlantic Health System, Morristown, NJ, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,2,16]]},"reference":[{"key":"2021021616380906600_ytab028-B1","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1001\/jama.2020.1585","article-title":"Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China","volume":"323","author":"Wang","year":"2020","journal-title":"JAMA"},{"key":"2021021616380906600_ytab028-B2","author":"Basu-Ray","year":"2020"},{"key":"2021021616380906600_ytab028-B3","doi-asserted-by":"crossref","first-page":"1798","DOI":"10.1093\/eurheartj\/ehaa231","article-title":"Coronaviruses and the cardiovascular system: acute and long-term implications","volume":"41","author":"Xiong","year":"2020","journal-title":"Eur Heart J"},{"key":"2021021616380906600_ytab028-B4","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1161\/CIRCRESAHA.115.306573","article-title":"Myocarditis","volume":"118","author":"Fung","year":"2016","journal-title":"Circ Res"},{"key":"2021021616380906600_ytab028-B5","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1016\/j.hrthm.2020.05.001","article-title":"Recognizing COVID-19-related myocarditis: the possible pathophysiology and proposed guideline for diagnosis and management","volume":"17","author":"Siripanthong","year":"2020","journal-title":"Heart Rhythm"},{"key":"2021021616380906600_ytab028-B6","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.cell.2020.02.052","article-title":"SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor","volume":"181","author":"Hoffmann","year":"2020","journal-title":"Cell"},{"key":"2021021616380906600_ytab028-B7","doi-asserted-by":"crossref","first-page":"e69","DOI":"10.1161\/CIR.0000000000000745","article-title":"Recognition and initial management of fulminant myocarditis: a scientific statement from the American Heart Association","volume":"141","author":"Kociol","year":"2020","journal-title":"Circulation"},{"key":"2021021616380906600_ytab028-B8","first-page":"30497","article-title":"Systematic review of COVID-19 related myocarditis: insights on management and outcome","author":"Sawalha","year":"2020","journal-title":"Cardiovasc Revasc Med"}],"container-title":["European Heart Journal - 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