{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T11:49:57Z","timestamp":1753876197414,"version":"3.41.2"},"reference-count":7,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2021,3,7]],"date-time":"2021-03-07T00:00:00Z","timestamp":1615075200000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,2,28]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n Left ventricular (LV) aneurysms complicate anterior myocardial infarctions (MIs) in 8\u201315% of cases. In case of associated LV dysfunction, rapidly evolving heart failure may follow, and urgent surgery becomes life-saving.<\/jats:p>\n <\/jats:sec>\n \n Case summary<\/jats:title>\n Following an acute anterior MI treated by percutaneous coronary intervention, which resulted in apical hypokinesis, depressed LV function, and moderate mitral regurgitation, a 70-year-old male patient kept in contact with our cardiology department through phone calls. Over 6 weeks, the patient's conditions worsened. For fear of contracting COVID-19, he refused to attend to the Emergency Room. Conditions did not improve despite medical therapy adjustments, and he was admitted to hospital following a syncope. Computed tomography scan revealed pneumonia, and he was placed in a \u2018grey\u2019 ward while waiting for nose-swab results for COVID-19. A rapid escalation of treatment was necessary as conditions did not improve with low-dose inotropes, and he required invasive ventilation. An Impella 5.0 was implanted as support prior to surgery, was maintained during the procedure and as a means of weaning off extracorporeal circulation. Surgery was successful and Impella 5.0 was removed on postoperative Day 5.<\/jats:p>\n <\/jats:sec>\n \n Discussion<\/jats:title>\n To date, Impella use in cardiothoracic surgery has been described in case of ventricular septal rupture or as a bridge to permanent LV assist device. In our case, Impella 5.0 was implanted, used as a bridge to surgery, and as postoperative support in a patient with evolving cardiogenic shock due to LV aneurysm and depressed LV ejection fraction following acute MI, in the difficult setting of the COVID-19 pandemic.<\/jats:p>\n <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytab037","type":"journal-article","created":{"date-parts":[[2021,3,11]],"date-time":"2021-03-11T04:44:17Z","timestamp":1615437857000},"source":"Crossref","is-referenced-by-count":5,"title":["Impella 5.0 support before, during, and after surgical ventriculoplasty following acute myocardial infarction in the COVID-19 era: a case report"],"prefix":"10.1093","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8010-4306","authenticated-orcid":false,"given":"Martina","family":"Briani","sequence":"first","affiliation":[{"name":"Department of Clinical and Interventional Cardiology, Humanitas Clinical and Research Centre, IRCCS, Via Alessandro Manzoni, 56, Rozzano, 20089 Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucia","family":"Torracca","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Humanitas Clinical and Research Centre, IRCCS, Via Alessandro Manzoni, 56, Rozzano, 20089 Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Crescenzi","sequence":"additional","affiliation":[{"name":"Department of Anesthesia and Intensive Care Medicine, Humanitas Clinical and Research Hospital, IRCCS, Via Alessandro Manzoni, 56, Rozzano, 20089 Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5120-5802","authenticated-orcid":false,"given":"Alessandro","family":"Barbone","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Humanitas Clinical and Research Centre, IRCCS, Via Alessandro Manzoni, 56, Rozzano, 20089 Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,3,7]]},"reference":[{"key":"2021031104313494200_ytab037-B1","volume-title":"Cardiac Surgey in the Adult","author":"Cohn","year":"2007","edition":"3rd ed."},{"key":"2021031104313494200_ytab037-B2","doi-asserted-by":"crossref","first-page":"i49","DOI":"10.1093\/ejcts\/ezy367","article-title":"Myocardial reconstruction in ischaemic cardiomyopathy","volume":"155","author":"Castelvecchio","year":"2019","journal-title":"Eur J Cardio-Thorac Surg"},{"key":"2021031104313494200_ytab037-B3","volume-title":"Kirklin\/Baratt-Boyes Cardiac Surgery","author":"Kouchoukos","year":"2012","edition":"4th ed."},{"year":"2018","author":"Mohite","key":"2021031104313494200_ytab037-B4"},{"key":"2021031104313494200_ytab037-B5","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1002\/ehf2.12622","article-title":"Early cardiac unloading with Impella CP in acute myocardial infarction with ventricular septal defect","volume":"7","author":"Via","year":"2020","journal-title":"ESC Heart Fail"},{"key":"2021031104313494200_ytab037-B6","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1016\/j.amjcard.2018.07.011","article-title":"Meta-analysis and trial sequential analysis comparing percutaneous ventricular assist devices versus intra-aortic balloon pump during high-risk percutaneous coronary intervention or cardiogenic shock","volume":"122","author":"Rios","year":"2018","journal-title":"Am J Cardiol"},{"key":"2021031104313494200_ytab037-B7","doi-asserted-by":"crossref","first-page":"e000987","DOI":"10.1136\/openhrt-2018-000987","article-title":"Skurk CImpella versus IABP in acute myocardial infarction complicated by cardiogenic shock","volume":"6","author":"Alushi","year":"2019","journal-title":"Open Heart"}],"container-title":["European Heart Journal - 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