{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T15:53:32Z","timestamp":1781279612442,"version":"3.54.1"},"reference-count":19,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2021,3,3]],"date-time":"2021-03-03T00:00:00Z","timestamp":1614729600000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,2,28]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Severe aortic regurgitation (AR) is an extremely rare complication after coronary catheterization and percutaneous coronary intervention (PCI), where most reported cases have required relatively urgent surgical intervention due to acute-onset AR and cardiac decompensation.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case summary<\/jats:title>\n                  <jats:p>We report a case of a 60-year-old woman that previously presented with a non-ST-elevation myocardial infarction (NSTEMI) due to an ostial right coronary artery stenosis. During the course of 2\u2009years, she developed five recurrent NSTEMI due to in-stent thrombosis, necessitating either a new coronary stent or balloon. She developed a chronic severe AR due to a drug-eluting coronary stent protruding from the right coronary artery and underwent successful aortic valve replacement and coronary artery by-pass grafting.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>We performed a literature review and identified 16 reported cases of iatrogenic severe aortic regurgitation related to coronary catheterization or percutaneous coronary intervention. All patients developed an acute aortic regurgitation and, thus, we report the first case of a delayed complication caused by a protruding coronary stent. The surgical strategy is related to the extent of the damage, where smaller perforations or lacerations seems to be feasible for aortic valve repair and larger defects more often lead to aortic valve replacement. Our patient developed a fibrotic right coronary cusp which could not be used to perform a successful aortic valve repair.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytab044","type":"journal-article","created":{"date-parts":[[2021,3,7]],"date-time":"2021-03-07T18:56:03Z","timestamp":1615143363000},"source":"Crossref","is-referenced-by-count":8,"title":["Severe chronic aortic regurgitation after percutaneous coronary intervention: a case report and literature review"],"prefix":"10.1093","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3867-8568","authenticated-orcid":false,"given":"Johan O","family":"Wedin","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic Surgery and Anesthesiology, Entrance 50, 7th Floor, Uppsala University Hospital, SE-75185 Uppsala, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8825-896X","authenticated-orcid":false,"given":"Per","family":"Vikholm","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery and Anesthesiology, Entrance 50, 7th Floor, Uppsala University Hospital, SE-75185 Uppsala, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0549-8103","authenticated-orcid":false,"given":"Ulrica","family":"Alstr\u00f6m","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery and Anesthesiology, Entrance 50, 7th Floor, Uppsala University Hospital, SE-75185 Uppsala, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1790-3711","authenticated-orcid":false,"given":"Petter","family":"Schiller","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery and Anesthesiology, Entrance 50, 7th Floor, Uppsala University Hospital, SE-75185 Uppsala, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,3,3]]},"reference":[{"key":"2021031118311602400_ytab044-B1","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1016\/S0002-9149(98)01064-9","article-title":"Prevalence and clinical determinants of mitral, tricuspid, and aortic regurgitation (the Framingham Heart Study)","volume":"83","author":"Singh","year":"1999","journal-title":"Am J Cardiol"},{"key":"2021031118311602400_ytab044-B2","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1136\/hrt.2004.042614","article-title":"Aortic regurgitation","volume":"92","author":"Maurer","year":"2006","journal-title":"Heart Br Card Soc"},{"key":"2021031118311602400_ytab044-B3","doi-asserted-by":"crossref","first-page":"3232","DOI":"10.1161\/CIRCULATIONAHA.108.782292","article-title":"Acute valvular regurgitation","volume":"119","author":"Stout","year":"2009","journal-title":"Circulation"},{"key":"2021031118311602400_ytab044-B4","doi-asserted-by":"crossref","first-page":"e8\u201311","DOI":"10.1161\/CIRCINTERVENTIONS.110.960369","article-title":"Severe aortic regurgitation after transradial percutaneous coronary intervention","volume":"4","author":"Ong","year":"2011","journal-title":"Circ Cardiovasc Interv"},{"key":"2021031118311602400_ytab044-B5","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1111\/jocs.14272","article-title":"Rare case of iatrogenic aortic valve leaflet tear following a diagnostic coronary angiogram","volume":"35","author":"Madigan","year":"2020","journal-title":"J Card Surg"},{"key":"2021031118311602400_ytab044-B6","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.4070\/kcj.2018.0136","article-title":"Pivotal role of intraoperative transesophageal echocardiography for detecting iatrogenic aortic regurgitation due to cardiac catheterization","volume":"48","author":"Kolla","year":"2018","journal-title":"Korean Circ J"},{"key":"2021031118311602400_ytab044-B7","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.recesp.2016.07.020","article-title":"Percutaneous coronary intervention: a rare cause of acute traumatic aortic regurgitation","volume":"70","author":"Gamaza Chuli\u00e1n","year":"2017","journal-title":"Rev Espanola Cardiol Engl Ed"},{"key":"2021031118311602400_ytab044-B8","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1111\/jocs.12846","article-title":"Aortic valve laceration following coronary angiography and percutaneous coronary intervention","volume":"31","author":"Roy","year":"2016","journal-title":"J Card Surg"},{"key":"2021031118311602400_ytab044-B9","first-page":"E22","article-title":"An unusual complication after coronary catheterization","volume":"24","author":"Grisoli","year":"2012","journal-title":"J Invasive Cardiol"},{"key":"2021031118311602400_ytab044-B10","doi-asserted-by":"crossref","first-page":"e3","DOI":"10.1016\/j.jacc.2011.11.076","article-title":"Aortic valve avulsion: uncommon complication of coronary angiography","volume":"60","author":"Shim","year":"2012","journal-title":"J Am Coll Cardiol"},{"key":"2021031118311602400_ytab044-B11","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1510\/icvts.2010.252155","article-title":"Aortic valve lesion after coronary angiography","volume":"12","author":"Rolf","year":"2011","journal-title":"Interact Cardiovasc Thorac Surg"},{"key":"2021031118311602400_ytab044-B12","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1111\/j.1540-8191.2011.01306.x","article-title":"Repair of iatrogenic aortic regurgitation following cardiac catheterization","volume":"26","author":"Bouabdallaoui","year":"2011","journal-title":"J Card Surg"},{"key":"2021031118311602400_ytab044-B13","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1016\/j.jcin.2010.04.018","article-title":"Aortic regurgitation after cardiac catheterization","volume":"3","author":"Safar","year":"2010","journal-title":"JACC Cardiovasc Interv"},{"key":"2021031118311602400_ytab044-B14","first-page":"717","article-title":"Delayed aortic regurgitation caused by a right coronary stent protruding into the aorta","volume":"18","author":"Quintana","year":"2009","journal-title":"J Heart Valve Dis"},{"key":"2021031118311602400_ytab044-B15","doi-asserted-by":"crossref","first-page":"1765","DOI":"10.1016\/j.athoracsur.2006.12.054","article-title":"Aortic valve as a victim of percutaneous coronary angioplasty and stenting","volume":"84","author":"Kotoulas","year":"2007","journal-title":"Ann Thorac Surg"},{"key":"2021031118311602400_ytab044-B16","first-page":"281","article-title":"Repair of aortic cusp traumatic laceration caused by cardiac catheterization","volume":"5","author":"Fundar\u00f2","year":"1996","journal-title":"J Heart Valve Dis"},{"key":"2021031118311602400_ytab044-B17","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1111\/j.1540-8191.1988.tb00233.x","article-title":"Pericardial patch repair of aortic cusp perforation caused by cardiac catheterization","volume":"3","author":"Denyer","year":"1988","journal-title":"J Cardiac Surgery"},{"key":"2021031118311602400_ytab044-B18","doi-asserted-by":"crossref","first-page":"1897","DOI":"10.1016\/j.jacc.2010.07.028","article-title":"In-stent restenosis in the drug-eluting stent era","volume":"56","author":"Dangas","year":"2010","journal-title":"J Am Coll Cardiol"},{"key":"2021031118311602400_ytab044-B19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/ehjcr\/ytaa001","article-title":"Repetitive restenosis in a biodegradable polymer sirolimus-eluting stent with hypersensitivity reaction: a case report","volume":"4","author":"Jimba","year":"2020","journal-title":"Eur Heart J - Case Rep"}],"container-title":["European Heart Journal - Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/ehjcr\/article-pdf\/5\/3\/ytab044\/36577836\/ytab044.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/ehjcr\/article-pdf\/5\/3\/ytab044\/36577836\/ytab044.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,11]],"date-time":"2021-03-11T18:31:41Z","timestamp":1615487501000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ehjcr\/article\/doi\/10.1093\/ehjcr\/ytab044\/6157090"}},"subtitle":[],"editor":[{"given":"Georg","family":"Goliasch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"Tina","family":"Khan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"Giuseppe","family":"Musumeci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"Hibba","family":"Kurdi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"Ross","family":"Thomson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2021,2,28]]},"references-count":19,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,2,28]]}},"URL":"https:\/\/doi.org\/10.1093\/ehjcr\/ytab044","relation":{},"ISSN":["2514-2119"],"issn-type":[{"value":"2514-2119","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2021,3,1]]},"published":{"date-parts":[[2021,2,28]]},"article-number":"ytab044"}}