{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T11:50:11Z","timestamp":1753876211224,"version":"3.41.2"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2021,6,5]],"date-time":"2021-06-05T00:00:00Z","timestamp":1622851200000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,5,29]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Catheter-based closure has emerged as a less invasive alternative to surgery in high-risk patients with paravalvular leak (PVL) and clinically significant regurgitation with feasibility and efficacy demonstrated in multiple studies.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case summary<\/jats:title>\n                  <jats:p>A 72-year-old female with a past history of long-standing rheumatic heart disease underwent mechanical mitral valve replacement in 2008. Ten years later, redo surgery was performed due to a worsening mitral PVL and the leakage was closed by direct pledget-supported sutures, preserving the mechanical valve. She was recently admitted again for haemolytic anaemia and congestive heart failure (New York Heart Association Classes III\u2013IV) due to a recurrent mitral PVL. We report our initial clinical experience using a novel software solution (EchoNavigator\u00ae-system) for intuitive guidance during a catheter-based transapical mitral PVL closure.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>Transapical mitral PVL closure with a specifically designed device demonstrated in our case to be a better option than redo surgery. Recently introduced fusion imaging modalities enhanced visualization of soft tissue anatomy and device location improving enormously the results of this challenging intervention.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytab190","type":"journal-article","created":{"date-parts":[[2021,6,5]],"date-time":"2021-06-05T19:08:50Z","timestamp":1622920130000},"source":"Crossref","is-referenced-by-count":2,"title":["EchoNavigator\u00ae technology facilitates transapical mitral paravalvular leak closure: a case report"],"prefix":"10.1093","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0511-9345","authenticated-orcid":false,"given":"Igor Vyacheslavovich","family":"Buzaev","sequence":"first","affiliation":[{"name":"Republican Heart Centre, Ufa, Russia"},{"name":"Bashkir State Medical University, Scientific Center of the Russian Academy of Science, Ufa, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1943-4971","authenticated-orcid":false,"given":"Gulchachak","family":"Khalikova","sequence":"additional","affiliation":[{"name":"Republican Heart Centre, Ufa, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6716-4048","authenticated-orcid":false,"given":"Vladimir Vyacheslavovich","family":"Plechev","sequence":"additional","affiliation":[{"name":"Republican Heart Centre, Ufa, Russia"},{"name":"Bashkir State Medical University, Scientific Center of the Russian Academy of Science, Ufa, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6750-5682","authenticated-orcid":false,"given":"Eustaquio Maria","family":"Onorato","sequence":"additional","affiliation":[{"name":"Bashkir State Medical University, Scientific Center of the Russian Academy of Science, Ufa, Russia"},{"name":"Centro Cardiologico Monzino, IRCCS University School of Milan, Via C. Parea, 4, 20138 Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,6,5]]},"reference":[{"key":"2021070816594527600_ytab190-B1","doi-asserted-by":"crossref","first-page":"2739","DOI":"10.1093\/eurheartj\/ehx391","article-title":"2017 ESC\/EACTS Guidelines for the management of valvular heart disease","volume":"38","author":"Baumgartner","year":"2017","journal-title":"Eur Heart J"},{"key":"2021070816594527600_ytab190-B2","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1161\/CIRCULATIONAHA.116.022684","article-title":"Percutaneous device closure of paravalvular leak: combined experience from the United Kingdom and Ireland","volume":"134","author":"Calvert","year":"2016","journal-title":"Circulation"},{"key":"2021070816594527600_ytab190-B3","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1253\/circj.CJ-15-0802","article-title":"Utility of real-time 3-dimensional transesophageal echocardiography in the assessment of mitral paravalvular leak","volume":"80","author":"Arribas-Jimenez","year":"2016","journal-title":"Circ J"},{"key":"2021070816594527600_ytab190-B4","doi-asserted-by":"crossref","first-page":"562","DOI":"10.4330\/wjc.v7.i9.562","article-title":"Initial clinical experience using the EchoNavigator-system during structural heart disease interventions","volume":"7","author":"Balzer","year":"2015","journal-title":"World J Cardiol"},{"key":"2021070816594527600_ytab190-B5","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.recesp.2017.10.041","article-title":"Fusion imaging for procedural guidance","volume":"71","author":"Wiley","year":"2018","journal-title":"Rev Esp Cardiol"},{"key":"2021070816594527600_ytab190-B6","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/j.jcin.2016.11.043","article-title":"Outcomes after paravalvular leak closure: transcatheter versus surgical approaches","volume":"10","author":"Wells","year":"2017","journal-title":"JACC Cardiovasc Interv"},{"key":"2021070816594527600_ytab190-B7","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.cjca.2014.12.012","article-title":"Transcatheter reduction of paravalvular leaks: a systematic review and meta-analysis","volume":"31","author":"Millan","year":"2015","journal-title":"Can J Cardiol"},{"key":"2021070816594527600_ytab190-B8","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.jtcvs.2015.11.046","article-title":"Long-term results after surgical treatment of paravalvular leak in the aortic and mitral position","volume":"151","author":"Bouhout","year":"2016","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2021070816594527600_ytab190-B9","first-page":"110","article-title":"Percutaneous management of paravalvular leaks: an alternative to surgery or first-line therapy","volume":"73","author":"Millan","year":"2020","journal-title":"Rev Esp Cardiol"},{"year":"2014","author":"Sharma","key":"2021070816594527600_ytab190-B10"},{"key":"2021070816594527600_ytab190-B11","first-page":"167","article-title":"Retrospective analysis of single-center early and midterm results of transapical catheter-based mitral paravalvular leak closure with a purpose-specific device","volume":"14","author":"Zorinas","year":"2018","journal-title":"Adv Interv Cardiol"},{"key":"2021070816594527600_ytab190-B12","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1002\/ccd.25992","article-title":"Multiplug paravalvular leak closure using Amplatzer Vascular Plugs III: a prospective registry","volume":"87","author":"Smolka","year":"2016","journal-title":"Catheter Cardiovasc Interv"},{"key":"2021070816594527600_ytab190-B13","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.4244\/EIJV11I10A237","article-title":"Early experience of percutaneous paravalvular leak closure using a novel Occlutech occluder","volume":"11","author":"Goktekin","year":"2016","journal-title":"EuroIntervention"},{"key":"2021070816594527600_ytab190-B14","first-page":"128","article-title":"Transcatheter closure of paravalvular leaks using a paravalvular leak device\u2014a prospective Polish registry","volume":"12","author":"Smolka","year":"2016","journal-title":"Adv Interv Cardiol"},{"key":"2021070816594527600_ytab190-B15","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.4244\/EIJ-D-19-00517","article-title":"Midterm procedural and clinical outcomes of percutaneous paravalvular leak closure with the Occlutech paravalvular leak device","volume":"15","author":"Onorato","year":"2020","journal-title":"EuroIntervention"}],"container-title":["European Heart Journal - 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