{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T11:50:16Z","timestamp":1753876216644,"version":"3.41.2"},"reference-count":3,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2021,8,15]],"date-time":"2021-08-15T00:00:00Z","timestamp":1628985600000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>An aortic sinus of Valsalva aneurysm (SVA) often remains undiagnosed until it ruptures. An SVA filled with thrombus can be challenging to diagnose accurately.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case summary<\/jats:title>\n                  <jats:p>A 70-year-old man was admitted with a clinical diagnosis of well-tolerated complete atrioventricular block (AVB). Transthoracic echocardiography revealed a spherical mass (43\u2009\u00d7\u200949\u2009mm) at the interatrial septum. Enhanced computed tomography (CT) showed a well-defined, hollow, and non-enhanced mass suggesting a cardiac tumour. However, 18F-fluorodeoxyglucose positron emission tomography\/CT (18F-FDG PET\/CT) showed no uptake in the mass. After implantation of a permanent pacemaker, anticoagulant therapy was started for paroxysmal atrial fibrillation. Two months later, follow-up evaluation by echocardiography and enhanced CT revealed an increase in size of the hollow interior cavity, suggesting thrombolysis by the anticoagulant. We diagnosed a non-coronary SVA filled with thrombus, which masqueraded as a cardiac tumour and may have caused complete AVB.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>We describe a rare case of a giant thrombosed SVA masquerading as a cardiac tumour. Initial 18F-FDG PET\/CT and serial imaging studies were helpful in distinguishing it from a cardiac tumour.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytab259","type":"journal-article","created":{"date-parts":[[2021,8,15]],"date-time":"2021-08-15T18:31:05Z","timestamp":1629052265000},"source":"Crossref","is-referenced-by-count":2,"title":["Thrombosed sinus of Valsalva aneurysm masquer ading as a cardiac tumour: a case report"],"prefix":"10.1093","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4936-074X","authenticated-orcid":false,"given":"Wakana","family":"Sato","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Medicine, Akita University Graduate School of Medicine, 1-1-1 Hondoh, Akita 010-8543, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsuhito","family":"Seki","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Akita University Graduate School of Medicine, 1-1-1 Hondoh, Akita 010-8543, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Akita University Graduate School of Medicine, 1-1-1 Hondoh, Akita 010-8543, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8690-2416","authenticated-orcid":false,"given":"Hiroyuki","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Akita University Graduate School of Medicine, 1-1-1 Hondoh, Akita 010-8543, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,8,15]]},"reference":[{"key":"2021081907105121200_ytab259-B1","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1016\/0002-8703(93)90141-U","article-title":"Ruptured congenital aneurysm of the sinus of valsalva with persistent left superior vena cava imaged by intraoperative transesophageal echocardiography","volume":"125","author":"Flynn","year":"1993","journal-title":"Am Heart J"},{"key":"2021081907105121200_ytab259-B2","doi-asserted-by":"crossref","first-page":"869","DOI":"10.4070\/kcj.2012.42.12.869","article-title":"Valsalva aneurysm filled with thrombi mimicking a cardiac tumor","volume":"42","author":"Lee","year":"2012","journal-title":"Korean Circ J"},{"key":"2021081907105121200_ytab259-B3","first-page":"281716","article-title":"Complete heart block with diastolic heart failure and pulmonary edema secondary to enlarging previously diagnosed thrombosed aneurysm of sinus of valsalva in a patient with history of autosomal dominant polycystic kidney disease","volume":"2015","author":"Eltawansy","year":"2015","journal-title":"Case Rep Cardiol"}],"container-title":["European Heart Journal - Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/ehjcr\/article-pdf\/5\/8\/ytab259\/39805155\/ytab259.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/ehjcr\/article-pdf\/5\/8\/ytab259\/39805155\/ytab259.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,19]],"date-time":"2021-08-19T07:11:27Z","timestamp":1629357087000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ehjcr\/article\/doi\/10.1093\/ehjcr\/ytab259\/6352641"}},"subtitle":[],"editor":[{"given":"Amardeep Ghosh","family":"Dastidar","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Stefan","family":"Simovic","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Nida","family":"Ahmed","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2021,8,1]]},"references-count":3,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2021,8,1]]}},"URL":"https:\/\/doi.org\/10.1093\/ehjcr\/ytab259","relation":{},"ISSN":["2514-2119"],"issn-type":[{"type":"electronic","value":"2514-2119"}],"subject":[],"published-other":{"date-parts":[[2021,8,1]]},"published":{"date-parts":[[2021,8,1]]},"article-number":"ytab259"}}