{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T11:50:21Z","timestamp":1753876221003,"version":"3.41.2"},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2021,10,8]],"date-time":"2021-10-08T00:00:00Z","timestamp":1633651200000},"content-version":"vor","delay-in-days":7,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,10,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Intra-cardiac masses are always a challenging diagnosis, especially when it involves the right side of the heart. There are multiples aetiologies that can be responsible for these masses, namely thrombosis, neoplasm, or vegetations. Occasionally, these may be related to an autoimmune process not yet diagnosed. We present a case of a 17-year-old patient with an exuberant right ventricular mass due to a not yet diagnosed Beh\u00e7et\u2019s disease. The best approach and treatment for these patients remains uncertain.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case summary<\/jats:title>\n                  <jats:p>The authors present a case of a 17-year-old patient with a right ventricular mass who presented as an initial manifestation of Beh\u00e7et\u2019s disease. It was firstly assumed as a thrombotic mass and medicated with anticoagulation, with no resolution. After performing a cardiac magnetic resonance, the case was discussed in a multidisciplinary team, including cardiology, paediatrics, and rheumatology, and the diagnosis of Beh\u00e7et\u2019s disease with cardiac complication was established. The patient started immunosuppressive therapy with clinical and echocardiographic response.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>Beh\u00e7et\u2019s disease is a multi-systemic autoimmune vasculitis that usually manifests by recurrent oral and genital ulcers as well as ocular symptoms. Cardiac manifestations are rare but important aspects of the course of the disease, especially in what concerns morbidity burden. The treatment of these cardiovascular complications is generally empirical and involves the treatment of the underlying disease.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytab299","type":"journal-article","created":{"date-parts":[[2021,10,10]],"date-time":"2021-10-10T20:51:39Z","timestamp":1633899099000},"source":"Crossref","is-referenced-by-count":2,"title":["Beh\u00e7et\u2019s disease: a case report about a rare cause of intra-cardiac mass"],"prefix":"10.1093","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8107-4658","authenticated-orcid":false,"given":"Alexandra","family":"Briosa","sequence":"first","affiliation":[{"name":"Cardiology Department, Hospital Garcia de Orta EPE, Av. Prof. Torrado da Silva, 2801-951 Almada, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7485-1244","authenticated-orcid":false,"given":"Ana Catarina","family":"Gomes","sequence":"additional","affiliation":[{"name":"Cardiology Department, Hospital Garcia de Orta EPE, Av. Prof. Torrado da Silva, 2801-951 Almada, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9560-7635","authenticated-orcid":false,"given":"Ana","family":"CastelBranco","sequence":"additional","affiliation":[{"name":"Pediatric Department, Hospital Garcia de Orta EPE, Av. Prof. Torrado da Silva, 2801-951 Almada, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5053-8218","authenticated-orcid":false,"given":"Margarida","family":"Cunha","sequence":"additional","affiliation":[{"name":"Rheumatology Department, Hospital Garcia de Orta EPE, Av. Prof. Torrado da Silva, 2801-951 Almada, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1897-452X","authenticated-orcid":false,"given":"Sandra","family":"Sousa","sequence":"additional","affiliation":[{"name":"Rheumatology Department, Hospital Garcia de Orta EPE, Av. Prof. Torrado da Silva, 2801-951 Almada, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2634-6777","authenticated-orcid":false,"given":"Ana Rita","family":"Almeida","sequence":"additional","affiliation":[{"name":"Cardiology Department, Hospital Garcia de Orta EPE, Av. Prof. Torrado da Silva, 2801-951 Almada, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo","family":"Calhau","sequence":"additional","affiliation":[{"name":"Pediatric Department, Hospital Garcia de Orta EPE, Av. Prof. Torrado da Silva, 2801-951 Almada, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8656-4883","authenticated-orcid":false,"given":"H\u00e9lder","family":"Pereira","sequence":"additional","affiliation":[{"name":"Cardiology Department, Hospital Garcia de Orta EPE, Av. Prof. Torrado da Silva, 2801-951 Almada, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,10,8]]},"reference":[{"key":"2021100804422486000_ytab299-B1","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1111\/jdv.12107","article-title":"The International Criteria for Beh\u00e7et\u2019s Disease (ICBD): a collaborative study of 27 countries on the sensitivity and specificity of the new criteria","volume":"28","author":"Davatchi","year":"2014","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"2021100804422486000_ytab299-B2","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1111\/1756-185X.12691","article-title":"Adult Behcet\u2019s disease in Iran: analysis of 6075 patients","volume":"19","author":"Davatchi","year":"2016","journal-title":"Int J Rheum Dis"},{"key":"2021100804422486000_ytab299-B3","doi-asserted-by":"crossref","first-page":"2057","DOI":"10.1111\/1756-185X.13465","article-title":"Beh\u00e7et\u2019s disease","volume":"21","author":"Davatchi","year":"2018","journal-title":"Int J Rheum Dis"},{"key":"2021100804422486000_ytab299-B4","first-page":"1078","article-title":"OJ. 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