{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T11:49:33Z","timestamp":1753876173745,"version":"3.41.2"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2021,9,13]],"date-time":"2021-09-13T00:00:00Z","timestamp":1631491200000},"content-version":"vor","delay-in-days":12,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,9,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Cardiac sarcoidosis (CS) is associated with poor prognosis, yet the clinical diagnosis is often challenging. Advanced cardiac imaging including cardiac magnetic resonance (CMR) and positron emission tomographic (PET) have emerged as useful modalities to diagnose CS.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case summary<\/jats:title>\n                  <jats:p>A 66-year-old woman presented with palpitations. A 24-h Holter monitor detected a high premature ventricular contraction burden of 25.6%. She underwent two transthoracic echocardiograms; both showed normal results. Stress perfusion CMR did not show any evidence of ischaemic aetiology; however, myocardial lesions detected by late gadolinium enhancement (LGE) imaging raised suspicion for CS. While there was no myocardial uptake of fluorodeoxyglucose (FDG) in subsequent cardiac PET, high FDG uptake was seen in hilar lymph nodes. Lymph node biopsy confirmed the diagnosis of sarcoidosis.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>Cardiac magnetic resonance and PET imaging are designed to evaluate different aspects CS pathophysiology. The characteristic LGE in the absence of increased FDG uptake suggested inactive CS with residual myocardial scarring.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytab300","type":"journal-article","created":{"date-parts":[[2021,9,13]],"date-time":"2021-09-13T08:03:35Z","timestamp":1631520215000},"source":"Crossref","is-referenced-by-count":1,"title":["Is positron emission tomography enough to rule out cardiac sarcoidosis? A case report"],"prefix":"10.1093","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5410-4479","authenticated-orcid":false,"given":"Siyi","family":"Huang","sequence":"first","affiliation":[{"name":"Internal Medicine, University of California, San Francisco, Fresno , 155 N Fresno St , Fresno, CA 93701, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siri","family":"Kunchakarra","sequence":"additional","affiliation":[{"name":"Cardiology, University of California, San Francisco, Fresno , 2335 E Kashian Ln , Fresno, CA 93701, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ankit","family":"Rathod","sequence":"additional","affiliation":[{"name":"Cardiology, University of California, San Francisco, Fresno , 2335 E Kashian Ln , Fresno, CA 93701, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,9,13]]},"reference":[{"key":"2022081608175683100_ytab300-B1","doi-asserted-by":"crossref","first-page":"1969","DOI":"10.1161\/CIRCULATIONAHA.109.851352","article-title":"Detection of myocardial damage in patients with sarcoidosis","volume":"120","author":"Patel","year":"2009","journal-title":"Circulation"},{"key":"2022081608175683100_ytab300-B2","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.jacc.2016.03.605","article-title":"Cardiac sarcoidosis","volume":"68","author":"Birnie","year":"2016","journal-title":"J Am Coll Cardiol"},{"key":"2022081608175683100_ytab300-B3","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1016\/j.hrthm.2014.03.043","article-title":"HRS expert consensus statement on the diagnosis and management of arrhythmias associated with cardiac sarcoidosis","volume":"11","author":"Birnie","year":"2014","journal-title":"Heart Rhythm"},{"key":"2022081608175683100_ytab300-B4","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.ahj.2008.09.009","article-title":"Cardiac sarcoidosis","volume":"157","author":"Kim","year":"2009","journal-title":"Am Heart J"},{"key":"2022081608175683100_ytab300-B5","doi-asserted-by":"crossref","first-page":"e007030","DOI":"10.1161\/CIRCIMAGING.117.007030","article-title":"Complementary value of cardiac magnetic resonance imaging and positron emission tomography\/computed tomography in the assessment of cardiac sarcoidosis","volume":"11","author":"Vita","year":"2018","journal-title":"Circ Cardiovasc Imaging"},{"key":"2022081608175683100_ytab300-B6","doi-asserted-by":"crossref","first-page":"1538","DOI":"10.1093\/eurheartj\/ehi180","article-title":"Focal uptake on 18F-fluoro-2-deoxyglucose positron emission tomography images indicates cardiac involvement of sarcoidosis","volume":"26","author":"Ishimaru","year":"2005","journal-title":"Eur Heart J"},{"key":"2022081608175683100_ytab300-B7","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1007\/s00259-007-0650-8","article-title":"Myocardial imaging with 18F-fluoro-2-deoxyglucose positron emission tomography and magnetic resonance imaging in sarcoidosis","volume":"35","author":"Ohira","year":"2008","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"2022081608175683100_ytab300-B8","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.jcmg.2012.10.021","article-title":"CMR imaging predicts death and other adverse events in suspected cardiac sarcoidosis","volume":"6","author":"Greulich","year":"2013","journal-title":"JACC Cardiovasc Imaging"},{"key":"2022081608175683100_ytab300-B9","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.jcmg.2016.05.009","article-title":"Prognostic value of myocardial scarring on CMR in patients with cardiac sarcoidosis","volume":"10","author":"Coleman","year":"2017","journal-title":"JACC Cardiovasc Imaging"},{"key":"2022081608175683100_ytab300-B10","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.amjcard.2020.08.007","article-title":"Utility of cardiac magnetic resonance imaging versus cardiac positron emission tomography for risk stratification for ventricular arrhythmias in patients with cardiac sarcoidosis","volume":"134","author":"Gowani","year":"2020","journal-title":"Am J Cardiol"}],"container-title":["European Heart Journal - Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ehjcr\/article-pdf\/5\/9\/ytab300\/45434612\/ytab300.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ehjcr\/article-pdf\/5\/9\/ytab300\/45434612\/ytab300.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,16]],"date-time":"2022-08-16T08:18:23Z","timestamp":1660637903000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ehjcr\/article\/doi\/10.1093\/ehjcr\/ytab300\/6369196"}},"subtitle":[],"editor":[{"given":"Parham","family":"Eshtehardi","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Danny","family":"van de Sande","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Erica","family":"Tirr","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Zahra Raisi","family":"Estabragh","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Brett Sydney","family":"Bernstein","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Katharine","family":"Kott","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2021,9,1]]},"references-count":10,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2021,9,4]]}},"URL":"https:\/\/doi.org\/10.1093\/ehjcr\/ytab300","relation":{},"ISSN":["2514-2119"],"issn-type":[{"type":"electronic","value":"2514-2119"}],"subject":[],"published-other":{"date-parts":[[2021,9,1]]},"published":{"date-parts":[[2021,9,1]]},"article-number":"ytab300"}}