{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T06:53:25Z","timestamp":1771656805417,"version":"3.50.1"},"reference-count":11,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2021,9,16]],"date-time":"2021-09-16T00:00:00Z","timestamp":1631750400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,10,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Aortic valve involvement is rare in patients with Beh\u00e7et\u2019 s disease (BD); however, recurrent prosthetic valve detachment after valve surgery has frequently been reported. We report a rare case of Beh\u00e7et\u2019s aortitis involving the aortic valve, mimicking active infective endocarditis (IE) with perivalvular abscess.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case summary<\/jats:title>\n                  <jats:p>A 16-year-old boy, with an unknown case of BD, presented with pyrexia of unknown origin, severe aortic valve regurgitation, vegetation, and perivalvular abscess in the aortic valve. All cultures tested negative for microorganisms. As we suspected IE, aortic valve replacement was performed. After the initial surgery, recurrent prosthetic valve detachment and pseudoaneurysm formation occurred, which resulted in the diagnosis of BD. The patient underwent a modified Bentall procedure, in which the valve conduit was proximally sutured to the left ventricular outflow tract instead of the aortic annulus. Immunosuppressive therapy was initiated on the 10th postoperative day. His condition became stable, and additional surgery was not required.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>The echocardiographic findings of Beh\u00e7et\u2019s aortitis involving the aortic valve resemble those of aortic valve IE. Modified Bentall procedure, combined with effective immunosuppressive therapy, may be useful in preventing prosthetic valve detachment.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytab315","type":"journal-article","created":{"date-parts":[[2021,9,16]],"date-time":"2021-09-16T14:52:56Z","timestamp":1631803976000},"source":"Crossref","is-referenced-by-count":2,"title":["An adolescent with Beh\u00e7et\u2019s aortitis mimicking infective endocarditis: a case report"],"prefix":"10.1093","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6422-2671","authenticated-orcid":false,"given":"Kaoru","family":"Hattori","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, Yamato Seiwa Hospital, 9-8-2 Minami-Rinkan, Yamato, Kanagawa 242-0006, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mimiko","family":"Tabata","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Yamato Seiwa Hospital, 9-8-2 Minami-Rinkan, Yamato, Kanagawa 242-0006, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tohru","family":"Nojiri","sequence":"additional","affiliation":[{"name":"Department of Surgery, Yamato Seiwa Hospital, 9-8-2 Minami-Rinkan, Yamato, Kanagawa 242-0006, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsushi","family":"Kurata","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Yamato Seiwa Hospital, 9-8-2 Minami-Rinkan, Yamato, Kanagawa 242-0006, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,9,16]]},"reference":[{"key":"2021100605452043200_ytab315-B1","doi-asserted-by":"crossref","first-page":"e147","DOI":"10.1016\/j.athoracsur.2012.11.027","article-title":"An adolescent with aortic regurgitation caused by Behcet\u2019s disease mimicking endocarditis","volume":"95","author":"Kang","year":"2013","journal-title":"Ann Thorac Surg"},{"key":"2021100605452043200_ytab315-B2","doi-asserted-by":"crossref","first-page":"578.e1\u20134","DOI":"10.1016\/j.echo.2005.12.012","article-title":"Behcet\u2019s aortitis mimicking aortic valve endocarditis with subaortic complications","volume":"19","author":"Shiran","year":"2006","journal-title":"J Am Soc Echocardiogr"},{"key":"2021100605452043200_ytab315-B3","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1111\/j.1540-8191.2011.01392.x","article-title":"Aortic regurgitation caused by Behcet\u2019s disease: surgical experience during an 11-year period","volume":"27","author":"Ma","year":"2012","journal-title":"J Card Surg"},{"key":"2021100605452043200_ytab315-B4","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1093\/rheumatology\/40.6.668","article-title":"Lack of association of HLA-B51 with a severe disease course in Behcet\u2019s disease","volume":"40","author":"G\u00fcl","year":"2001","journal-title":"Rheumatology (Oxford)"},{"key":"2021100605452043200_ytab315-B5","doi-asserted-by":"crossref","first-page":"399","DOI":"10.4070\/kcj.2011.41.7.399","article-title":"Aseptic endocarditis in Behcet\u2019s disease presenting as tricuspid valve stenosis","volume":"41","author":"Lee","year":"2011","journal-title":"Korean Circ J"},{"key":"2021100605452043200_ytab315-B6","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1016\/j.echo.2009.07.025","article-title":"Behcet\u2019s disease as a frequently unrecognized cause of aortic regurgitation: suggestive and misleading echocardiography findings","volume":"22","author":"Han","year":"2009","journal-title":"J Am Soc Echocardiogr"},{"key":"2021100605452043200_ytab315-B7","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.jccase.2020.06.005","article-title":"Early detachment of prosthetic aortic valve one year after replacement for severe aortic regurgitation due to perforated aortic valve aneurysm; 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