{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,30]],"date-time":"2025-08-30T16:21:03Z","timestamp":1756570863008,"version":"3.41.2"},"reference-count":11,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2021,9,7]],"date-time":"2021-09-07T00:00:00Z","timestamp":1630972800000},"content-version":"vor","delay-in-days":6,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Universit\u00e4tsmedizin Essen Clinician Scientist Acedemy"},{"DOI":"10.13039\/501100001659","name":"German Research Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,9,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background\u2003<\/jats:title>\n                  <jats:p>Ventricular arrhythmia in left ventricular assist device (LVAD) recipients represents a challenging clinical scenario and the optimal treatment strategy in this unique patient population still needs to be defined.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case summary\u2003<\/jats:title>\n                  <jats:p>We report on a 61-year-old LVAD patient with incessant ventricular fibrillation (VF) despite multiple unsuccessful attempts to restore normal rhythm with external defibrillation and antiarrhythmic medication. He remained initially stable as an outpatient and subsequently developed secondary organ failure.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion\u2003<\/jats:title>\n                  <jats:p>This case demonstrates that under LVAD support long-term haemodynamic stability is possible even in case of VF, a situation that resembles Fontan circulation. However, ventricular arrhythmias are associated with a high risk of secondary organ damage due to right heart failure if left untreated. In case of refractory ventricular tachycardia or electrical storm listing for heart transplantation with high priority status should be pursued when possible. Alternatively, catheter ablation may be considered in selected cases and be performed in experienced centres in close collaboration with all involved specialists.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytab337","type":"journal-article","created":{"date-parts":[[2021,9,7]],"date-time":"2021-09-07T14:51:24Z","timestamp":1631026284000},"source":"Crossref","is-referenced-by-count":5,"title":["Case report: incessant ventricular fibrillation in a conscious left ventricular assist device patient"],"prefix":"10.1093","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0275-7344","authenticated-orcid":false,"given":"Aiste Monika","family":"Jakstaite","sequence":"first","affiliation":[{"name":"Department of Cardiology and Vascular Medicine, West German Heart and Vascular Center, University Hospital Essen, Hufelandstrasse 55, 45147 Essen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Luedike","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Vascular Medicine, West German Heart and Vascular Center, University Hospital Essen, Hufelandstrasse 55, 45147 Essen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reza","family":"Wakili","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Vascular Medicine, West German Heart and Vascular Center, University Hospital Essen, Hufelandstrasse 55, 45147 Essen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon","family":"Kochh\u00e4user","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Vascular Medicine, West German Heart and Vascular Center, University Hospital Essen, Hufelandstrasse 55, 45147 Essen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2725-9912","authenticated-orcid":false,"given":"Arjang","family":"Ruhparwar","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, West German Heart and Vascular Center, University Hospital Essen, Hufelandstrasse 55, 45147 Essen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8001-0265","authenticated-orcid":false,"given":"Tienush","family":"Rassaf","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Vascular Medicine, West German Heart and Vascular Center, University Hospital Essen, Hufelandstrasse 55, 45147 Essen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Papathanasiou","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Vascular Medicine, West German Heart and Vascular Center, University Hospital Essen, Hufelandstrasse 55, 45147 Essen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,9,7]]},"reference":[{"key":"2021091304014760800_ytab337-B1","doi-asserted-by":"crossref","first-page":"e967","DOI":"10.1161\/CIR.0000000000000673","article-title":"Device therapy and arrhythmia management in left ventricular assist device recipients: a scientific statement from the American Heart Association","volume":"139","author":"Gopinathannair","year":"2019","journal-title":"Circulation"},{"key":"2021091304014760800_ytab337-B2","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1161\/CIRCEP.113.000457","article-title":"The role of implantable cardioverter-defibrillators in patients with continuous flow left ventricular assist devices","volume":"6","author":"Enriquez","year":"2013","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"2021091304014760800_ytab337-B3","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1016\/j.jacep.2018.05.006","article-title":"Predictors and clinical impact of late ventricular arrhythmias in patients with continuous-flow left ventricular assist devices","volume":"4","author":"Galand","year":"2018","journal-title":"JACC Clin Electrophysiol"},{"key":"2021091304014760800_ytab337-B4","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.1016\/j.hrthm.2019.06.021","article-title":"Incidence, predictors, and clinical impact of electrical storm in patients with left ventricular assist devices: new insights from the ASSIST-ICD study","volume":"16","author":"Martins","year":"2019","journal-title":"Heart Rhythm"},{"key":"2021091304014760800_ytab337-B5","doi-asserted-by":"crossref","first-page":"e009091","DOI":"10.1161\/JAHA.118.009091","article-title":"Cardiac resynchronization therapy and clinical outcomes in continuous flow left ventricular assist device recipients","volume":"7","author":"Gopinathannair","year":"2018","journal-title":"J Am Heart Assoc"},{"key":"2021091304014760800_ytab337-B6","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1097\/MAT.0000000000000739","article-title":"Implantable cardioverter defibrillators and survival in continuous-flow left ventricular assist device patients","volume":"65","author":"Kutyifa","year":"2019","journal-title":"ASAIO J"},{"key":"2021091304014760800_ytab337-B7","doi-asserted-by":"crossref","first-page":"e015897","DOI":"10.1161\/JAHA.119.015897","article-title":"Postimplant phosphodiesterase type 5 inhibitors use is associated with lower rates of thrombotic events after left ventricular assist device implantation","volume":"9","author":"Xanthopoulos","year":"2020","journal-title":"J Am Heart Assoc"},{"key":"2021091304014760800_ytab337-B8","doi-asserted-by":"crossref","first-page":"107619","DOI":"10.1016\/j.pharmthera.2020.107619","article-title":"Off-label use of pulmonary vasodilators after left ventricular assist device implantation: calling in the evidence","volume":"214","author":"Papathanasiou","year":"2020","journal-title":"Pharmacol Ther"},{"key":"2021091304014760800_ytab337-B9","doi-asserted-by":"crossref","first-page":"1412","DOI":"10.1016\/j.jacep.2017.05.012","article-title":"Characterization of ventricular tachycardia after left ventricular assist device implantation as destination therapy: a single-center ablation experience","volume":"3","author":"Moss","year":"2017","journal-title":"JACC Clin Electrophysiol"},{"key":"2021091304014760800_ytab337-B10","doi-asserted-by":"crossref","first-page":"2325","DOI":"10.1056\/NEJMoa1613773","article-title":"Noninvasive cardiac radiation for ablation of ventricular tachycardia","volume":"377","author":"Cuculich","year":"2017","journal-title":"N Engl J Med"},{"key":"2021091304014760800_ytab337-B11","first-page":"443","article-title":"Cardiac sympathetic denervation for refractory ventricular arrhythmia in continuous-flow left ventricular assist device","volume":"3","author":"Vlismas","year":"2021","journal-title":"J Am Coll Cardiol Case Rep"}],"container-title":["European Heart Journal - Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/ehjcr\/advance-article-pdf\/doi\/10.1093\/ehjcr\/ytab337\/40324450\/ytab337.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/ehjcr\/article-pdf\/5\/9\/ytab337\/40352100\/ytab337.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/ehjcr\/article-pdf\/5\/9\/ytab337\/40352100\/ytab337.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,13]],"date-time":"2021-09-13T04:02:01Z","timestamp":1631505721000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ehjcr\/article\/doi\/10.1093\/ehjcr\/ytab337\/6365934"}},"subtitle":[],"editor":[{"given":"Takeshi","family":"Kitai","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Laszlo","family":"Gobolos","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Aref Bin","family":"Abdulhak","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Rahul","family":"Mukherjee","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Vishal Shahil","family":"Mehta","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2021,9,1]]},"references-count":11,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2021,9,4]]}},"URL":"https:\/\/doi.org\/10.1093\/ehjcr\/ytab337","relation":{},"ISSN":["2514-2119"],"issn-type":[{"type":"electronic","value":"2514-2119"}],"subject":[],"published-other":{"date-parts":[[2021,9,1]]},"published":{"date-parts":[[2021,9,1]]},"article-number":"ytab337"}}