{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T11:49:39Z","timestamp":1753876179087,"version":"3.41.2"},"reference-count":5,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2021,10,18]],"date-time":"2021-10-18T00:00:00Z","timestamp":1634515200000},"content-version":"vor","delay-in-days":17,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,10,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Cardiac involvement of Lyme disease (LD) typically results in atrioventricular (AV) conduction disturbance, mainly third-degree AV block.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case summary<\/jats:title>\n                  <jats:p>A 54-year-old patient presented to our emergency department due to recurrent syncope. Third-degree AV block with a ventricular escape rhythm (33 b.p.m.) was identified as the underlying rhythm. Transthoracic echocardiography (TTE) was normal. To rule out common reversible causes of complete AV block, a screening test for Lyme borreliosis was carried out. Elevated levels for borrelia IgG\/IgM were found and confirmed by western blot analysis. Lyme carditis (LC) was postulated as the most likely cause of the third-degree AV block given the young age of the patient. Initiation of antibiotic therapy with ceftriaxone resulted in a gradual normalization of the AV conduction with stable first-degree AV block on Day 6 of therapy. The patient was changed on oral antibiotics (doxycycline) and discharged without a pacemaker. After 3\u2009months, the AV conduction recovered to normal.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>Lyme carditis should always be considered, particularly in younger patients with new-onset AV block and without evidence of structural heart disease. Atrioventricular block recovers in the majority of cases after appropriate antibiotic treatment.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytab372","type":"journal-article","created":{"date-parts":[[2021,10,20]],"date-time":"2021-10-20T20:05:36Z","timestamp":1634760336000},"source":"Crossref","is-referenced-by-count":1,"title":["A rare and reversible cause of third-degree atrioventricular block: a case report"],"prefix":"10.1093","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3647-0405","authenticated-orcid":false,"given":"Gino","family":"Lee","sequence":"first","affiliation":[{"name":"University Hospital Basel Department of Cardiology, , Petersgraben 4, 4031 Basel, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"Badertscher","sequence":"additional","affiliation":[{"name":"University Hospital Basel Department of Cardiology, , Petersgraben 4, 4031 Basel, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8428-7050","authenticated-orcid":false,"given":"Christian","family":"Sticherling","sequence":"additional","affiliation":[{"name":"University Hospital Basel Department of Cardiology, , Petersgraben 4, 4031 Basel, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9240-6731","authenticated-orcid":false,"given":"Stefan","family":"Osswald","sequence":"additional","affiliation":[{"name":"University Hospital Basel Department of Cardiology, , Petersgraben 4, 4031 Basel, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,10,18]]},"reference":[{"key":"2022081608475759200_ytab372-B1","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.idc.2007.12.008","article-title":"Lyme carditis","volume":"22","author":"Fish","year":"2008","journal-title":"Infect Dis Clin North Am"},{"key":"2022081608475759200_ytab372-B2","doi-asserted-by":"crossref","first-page":"1611","DOI":"10.1002\/clc.23102","article-title":"Suspicious index in Lyme carditis: systematic review and proposed new risk score","volume":"41","author":"Besant","year":"2018","journal-title":"Clin Cardiol"},{"key":"2022081608475759200_ytab372-B3","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1093\/cid\/ciu411","article-title":"Third-degree heart block associated with Lyme carditis: review of published cases","volume":"59","author":"Forrester","year":"2014","journal-title":"Clin Infect Dis"},{"key":"2022081608475759200_ytab372-B4","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1016\/j.jacc.2018.11.035","article-title":"Diagnosis and treatment of Lyme carditis","volume":"73","author":"Yeung","year":"2019","journal-title":"J Am Coll Cardiol"},{"key":"2022081608475759200_ytab372-B5","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1086\/508667","article-title":"The clinical assessment, treatment, and prevention of Lyme disease, human granulocytic anaplasmosis, and babesiosis: clinical practice guidelines by the Infectious Diseases Society of America","volume":"43","author":"Wormser","year":"2006","journal-title":"Clin Infect Dis"}],"container-title":["European Heart Journal - 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