{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T14:51:53Z","timestamp":1778251913668,"version":"3.51.4"},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2022,5,17]],"date-time":"2022-05-17T00:00:00Z","timestamp":1652745600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,7,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Patients with a cardiac implantable electronic device (CIED)-induced tricuspid regurgitation (TR) have an increased mortality and morbidity. However, the impact of CIED-lead extraction and its indications are not well-defined.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case summary<\/jats:title>\n                  <jats:p>A 69-year-old woman presented with recurrent hospital admissions for right heart failure refractory to medical therapy, on the background of a single-chamber permanent pacemaker (Biotronik) implanted 6 years ago for tachycardia\u2013bradycardia syndrome. Transoesophageal echocardiography identified severe TR which was predominantly CIED-induced from a lead impingement of the posterior tricuspid valve (TV) leaflet preventing adequate leaflet coaptation. This had progressed to cause a degree of secondary functional TR. The patient underwent pacing lead extraction followed by epicardial lead placement via minithoracotomy, with significant symptomatic and echographic improvement of TR.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>CIED-induced TR from a lead impingement of TV leaflets carries the highest risk of TR and its consequences. This case illustrates the significance of the relationship between CIED-leads and the TV, which impacts management strategy. We recommend a mechanistic approach and incorporating CIED-lead interaction with the TV apparatus as the underlying principle in developing future management guidelines for CIED-induced TR.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytac170","type":"journal-article","created":{"date-parts":[[2022,5,17]],"date-time":"2022-05-17T23:15:41Z","timestamp":1652829341000},"source":"Crossref","is-referenced-by-count":4,"title":["Pacing lead extraction in the management of tricuspid regurgitation: a case report"],"prefix":"10.1093","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6299-7182","authenticated-orcid":false,"given":"Lynn","family":"Khor","sequence":"first","affiliation":[{"name":"Macquarie University Macquarie University Hospital, 3 Technology Place, , Sydney, NSW 2109 , Australia"},{"name":"Cardiology Department, Nepean Hospital , Derby Street, Kingswood, NSW 2747 , 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Department, Royal Prince Alfred Hospital , Missenden Road, Camperdown, NSW 2050 , Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,5,17]]},"reference":[{"key":"2022091611071859600_ytac170-B1","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1016\/S0002-9149(98)00567-0","article-title":"Increased prevalence of significant tricuspid regurgitation in patients with transvenous pacemakers leads","volume":"82","author":"Paniagua","year":"1998","journal-title":"Am J Cardiol"},{"key":"2022091611071859600_ytac170-B2","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1136\/heartjnl-2013-304673","article-title":"Significant lead-induced tricuspid regurgitation is associated with poor prognosis at long-term 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