{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T11:50:51Z","timestamp":1753876251160,"version":"3.41.2"},"reference-count":11,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,7,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Diagnosis and management of low-flow\/low-gradient aortic stenosis are very challenging. Resting echocardiography is not capable of differentiating between different types and origins of low-flow and low-gradient state in aortic valve stenosis. Therefore, dobutamine stress echocardiography (DSE) and cardiac computed tomography (CCT) are necessary. This case report should illustrate the importance of these assessments.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case summary<\/jats:title>\n                  <jats:p>A 73-year-old woman presented to our emergency department with New York Heart Association III symptoms of exertional dyspnoea. In addition, the patient complained of fatigue and low resilience. On physical examination, auscultation revealed a systolic murmur over the aortic valve. Further diagnostic steps revealed a low-flow\/low-gradient aortic valve stenosis (LF\/LGAS) without contractile reserve (CR) in DSE and massive valve calcification in CCT.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>In this case, we demonstrate the importance of different assessments and workflow. The prognosis of LF\/LGAS has been re-evaluated during the last decade and the current guidelines recommend the treatment of such patients even in the absence of CR. Furthermore, we are discussing the results of LF\/LGAS.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytac273","type":"journal-article","created":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T16:56:57Z","timestamp":1656694617000},"source":"Crossref","is-referenced-by-count":0,"title":["Low-flow\/low-gradient aortic stenosis without contractile reserve\u2014a case report"],"prefix":"10.1093","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9173-7336","authenticated-orcid":false,"given":"Lukas","family":"Stastny","sequence":"first","affiliation":[{"name":"Department of Cardiac surgery, Medical University Innsbruck , Anichstra\u00dfe 35 , Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1263-6909","authenticated-orcid":false,"given":"Julia","family":"Dumfarth","sequence":"additional","affiliation":[{"name":"Department of Cardiac surgery, Medical University Innsbruck , Anichstra\u00dfe 35 , Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guy","family":"Friedrich","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine III, Medical University Innsbruck , 6020 Innsbruck , Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7656-5812","authenticated-orcid":false,"given":"Nikolaos","family":"Bonaros","sequence":"additional","affiliation":[{"name":"Department of Cardiac surgery, Medical University Innsbruck , Anichstra\u00dfe 35 , Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,7,1]]},"reference":[{"key":"2022071812340240100_ytac273-B1","doi-asserted-by":"publisher","first-page":"2329","DOI":"10.1016\/j.jacc.2013.08.1621","article-title":"The complex nature of discordant severe calcified aortic valve disease grading: new insights from combined Doppler echocardiographic and computed tomographic 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