{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T11:50:13Z","timestamp":1753876213462,"version":"3.41.2"},"reference-count":7,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2022,7,29]],"date-time":"2022-07-29T00:00:00Z","timestamp":1659052800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,8,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Patients with Darier disease often present with staphylococcal skin infections and are at risk for complications when they undergo cardiothoracic surgery, such as acute aortic dissection repair.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case summary<\/jats:title>\n                  <jats:p>A 39-year-old woman with hypertension and Darier disease suffered an acute type A aortic dissection, requiring emergency operation with a Dacron graft. Twenty-five days post-operatively, she developed pneumonia and staph hominis was isolated in blood cultures and Bronchoalveolar Lavage. Following completion of antibiotics, multiple relapses occurred during a 6-month period, each time treated with appropriate antibiotic therapy. An 18F-fluorodeoxyglucose positron emission tomography computerized tomography showed persistent graft uptake and re-operation was performed. At 22 months of follow-up, the patient remains asymptomatic and the 18F-FDG PET\/CT shows significant reduction in FDG uptake.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>Graft infection is a rare but serious complication. Antibiotic therapy is often inadequate and re-operation is needed. As staphylococcal skin infections often occur in patients with Darier disease, adequate preprocedural skin preparation and sterilization are very important in these patients.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytac314","type":"journal-article","created":{"date-parts":[[2022,7,29]],"date-time":"2022-07-29T04:59:06Z","timestamp":1659070746000},"source":"Crossref","is-referenced-by-count":1,"title":["Infected thoracic aortic graft in a woman with Darier disease: a case report"],"prefix":"10.1093","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4823-7499","authenticated-orcid":false,"given":"Eftihia","family":"Sbarouni","sequence":"first","affiliation":[{"name":"Onassis Cardiac Surgery Center , 356 Sygrou Ave, Athens 17674 , Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Petraki","sequence":"additional","affiliation":[{"name":"Mediterraneo Hospital , 8-10 Ilias Str, Athens 16675 , Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Stavridis","sequence":"additional","affiliation":[{"name":"Onassis Cardiac Surgery Center , 356 Sygrou Ave, Athens 17674 , Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Athanassios","family":"Manginas","sequence":"additional","affiliation":[{"name":"Mediterraneo Hospital , 8-10 Ilias Str, Athens 16675 , Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,7,29]]},"reference":[{"key":"2022080617404109500_ytac314-B1","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1111\/jdv.12025","article-title":"Bacteriological aspects of darier\u2019s disease","volume":"27","author":"Dodiuk-Gad","year":"2013","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"2022080617404109500_ytac314-B2","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1007\/s40257-018-0362-9","article-title":"Coagulase-negative staphylococcal skin and soft tissue infections","volume":"19","author":"Natsis","year":"2018","journal-title":"Am J Clin Dermatol"},{"key":"2022080617404109500_ytac314-B3","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/0190-9622(92)70154-8","article-title":"Darier-White disease: a review of the clinical features in 163 patients","volume":"27","author":"Burge","year":"1992","journal-title":"J Am Acad Dermatol"},{"key":"2022080617404109500_ytac314-B4","doi-asserted-by":"crossref","first-page":"3016","DOI":"10.1016\/j.avsg.2018.02.038","article-title":"Current evidence on management of aortic stent-graft infection: a systemic review and meta-analysis","volume":"51","author":"Li","year":"2018","journal-title":"Ann Vasc Surg"},{"key":"2022080617404109500_ytac314-B5","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1093\/ejcts\/ezw190","article-title":"Endocarditis in patients with ascending aortic prosthetic graft: a case series from a national multicentre registry","volume":"50","author":"Ramos","year":"2016","journal-title":"Eur J Cardiothorac Surg"},{"key":"2022080617404109500_ytac314-B6","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1093\/icvts\/ivv178","article-title":"The relevance of 18F-fluorodeoxyglucose positron emission tomography\/computed tomography imaging in diagnosing prosthetic graft infections post cardiac and proximal thoracic aortic surgery","volume":"21","author":"Guenther","year":"2015","journal-title":"Interact Cardiovasc Thorac Surg"},{"key":"2022080617404109500_ytac314-B7","doi-asserted-by":"crossref","first-page":"418","DOI":"10.5761\/atcs.ra.15-00187","article-title":"Multidisciplinary treatment approach for prosthetic vascular graft infection in the thoracic aortic area","volume":"21","author":"Fujii","year":"2105","journal-title":"Ann Thorac Cardiovasc Surg"}],"container-title":["European Heart Journal - 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