{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T14:25:51Z","timestamp":1790259951038,"version":"4.1.0"},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2022,11,22]],"date-time":"2022-11-22T00:00:00Z","timestamp":1669075200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,12,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Catastrophic antiphospholipid syndrome and lupus myocarditis are two rare life-threatening conditions.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case summary<\/jats:title>\n                  <jats:p>We present a case of a 47-year-old woman admitted in profound cardiogenic shock due to catastrophic antiphospholipid syndrome and lupus myocarditis requiring advanced heart failure therapies, including early mechanical circulatory support. She improved with steroids, immunoglobulins, mycophenolate, and eculizumab.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>This case highlights the importance of early identification of cardiogenic shock secondary to catastrophic antiphospholipid syndrome and lupus myocarditis, the arrhythmogenic complications of myocarditis, and the subsequent management of the disease progression with mechanical and medical support.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytac446","type":"journal-article","created":{"date-parts":[[2022,11,22]],"date-time":"2022-11-22T05:29:44Z","timestamp":1669094984000},"source":"Crossref","is-referenced-by-count":7,"title":["A case report of acute heart failure and cardiogenic shock caused by catastrophic antiphospholipid syndrome and lupus myocarditis"],"prefix":"10.1093","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3135-0858","authenticated-orcid":false,"given":"Ashton C","family":"Lai","sequence":"first","affiliation":[{"name":"Icahn School of Medicine, Mount Sinai Medical Center , 1190 5th Avenue, New York, NY 10029-6574 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7964-1502","authenticated-orcid":false,"given":"Jason","family":"Feinman","sequence":"additional","affiliation":[{"name":"Icahn School of Medicine, Mount Sinai Medical Center , 1190 5th Avenue, New York, NY 10029-6574 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2250-4608","authenticated-orcid":false,"given":"Connor","family":"Oates","sequence":"additional","affiliation":[{"name":"Icahn School of Medicine, Mount Sinai Medical Center , 1190 5th Avenue, New York, NY 10029-6574 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aditya","family":"Parikh","sequence":"additional","affiliation":[{"name":"Icahn School of Medicine, Mount Sinai Medical Center , 1190 5th Avenue, New York, NY 10029-6574 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,11,22]]},"reference":[{"key":"2022122213012748500_ytac446-B1","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1136\/ard.2004.025759","article-title":"Validation of the preliminary criteria for the classification of catastrophic antiphospholipid syndrome","volume":"64","author":"Cervera","year":"2005","journal-title":"Ann Rheum Dis"},{"key":"2022122213012748500_ytac446-B2","doi-asserted-by":"crossref","first-page":"1594","DOI":"10.1177\/0961203320951260","article-title":"16th International congress on antiphospholipid antibodies task force report on catastrophic antiphospholipid syndrome","volume":"29","author":"Cervera","year":"2020","journal-title":"Lupus"},{"key":"2022122213012748500_ytac446-B3","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1093\/rheumatology\/kem371","article-title":"Associated factors and impact of myocarditis in patients with SLE from LUMINA, a multiethnic US cohort (LV). [corrected]","volume":"47","author":"Apte","year":"2008","journal-title":"Rheumatology (Oxford)"},{"key":"2022122213012748500_ytac446-B4","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1177\/0961203319871099","article-title":"Systemic lupus and catastrophic antiphospholipid syndrome manifesting as cardiogenic shock","volume":"28","author":"Schultz","year":"2019","journal-title":"Lupus"},{"key":"2022122213012748500_ytac446-B5","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1007\/s13224-017-0974-7","article-title":"Rare presentation of catastrophic antiphospholipid syndrome with myocarditis in post-partum period: case report and review of literature","volume":"68","author":"Girish","year":"2018","journal-title":"J Obstet Gynaecol India"},{"key":"2022122213012748500_ytac446-B6","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1177\/2048872612471215","article-title":"Hydroxychloroquine cardiotoxicity presenting as a rapidly evolving biventricular cardiomyopathy: key diagnostic features and literature review","volume":"2","author":"Joyce","year":"2013","journal-title":"Eur Heart J Acute Cardiovasc Care"},{"key":"2022122213012748500_ytac446-B7","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1093\/rheumatology\/key082","article-title":"The effect of triple therapy on the mortality of catastrophic anti-phospholipid syndrome patients","volume":"57","author":"Rodr\u00edguez-Pint\u00f3","year":"2018","journal-title":"Rheumatology"},{"key":"2022122213012748500_ytac446-B8","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1007\/s10238-019-00565-8","article-title":"Eculizumab in refractory catastrophic antiphospholipid syndrome: a case report and systematic review of the literature","volume":"19","author":"Tinti","year":"2019","journal-title":"Clin Exp Med"},{"key":"2022122213012748500_ytac446-B9","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1136\/ard.62.6.530","article-title":"Long term outcome of catastrophic antiphospholipid syndrome survivors","volume":"62","author":"Erkan","year":"2003","journal-title":"Ann Rheum Dis"}],"container-title":["European Heart Journal - Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ehjcr\/advance-article-pdf\/doi\/10.1093\/ehjcr\/ytac446\/47175179\/ytac446.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ehjcr\/article-pdf\/6\/12\/ytac446\/48346918\/ytac446.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ehjcr\/article-pdf\/6\/12\/ytac446\/48346918\/ytac446.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,22]],"date-time":"2022-12-22T13:02:12Z","timestamp":1671714132000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ehjcr\/article\/doi\/10.1093\/ehjcr\/ytac446\/6835931"}},"subtitle":[],"editor":[{"given":"Diego","family":"Araiza-Garaygordobil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"Edin","family":"Begic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"Diego","family":"Araiza-Garaygordobil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"Linh","family":"Ngo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"Aiste Monika","family":"Jakstaite","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2022,11,22]]},"references-count":9,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2022,12,6]]}},"URL":"https:\/\/doi.org\/10.1093\/ehjcr\/ytac446","relation":{},"ISSN":["2514-2119"],"issn-type":[{"value":"2514-2119","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2022,12,1]]},"published":{"date-parts":[[2022,11,22]]},"article-number":"ytac446"}}