{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T04:35:50Z","timestamp":1766378150296,"version":"3.41.2"},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2023,2,28]],"date-time":"2023-02-28T00:00:00Z","timestamp":1677542400000},"content-version":"vor","delay-in-days":29,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,2,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Non-calcified aortic stenosis (AS) is rare and is associated with a high risk of transcatheter valve embolization and migration (TVEM) because aortic valve complex calcification is important for stable anchoring of the prosthesis. Therefore, transcatheter aortic valve implantation (TAVI) for non-calcified AS is not preferred. However, a universally accepted strategy for TAVI in such patients is not yet established.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case summary<\/jats:title><jats:p>A 69-year-old woman with symptomatic severe AS and a high surgical risk was admitted to our institution for TAVI. Pre-procedural computed tomography (CT) revealed a non-calcified bicuspid aortic valve. Implantation of a 23\u2005mm self-expandable valve (SEV) was planned according to the manufacturer\u2019s recommended optimal size based on CT measurements. Intraoperatively, the 23\u2005mm SEV did not snugly fit at the aortic apparatus level. Thus, we deployed a 26\u2005mm SEV with stable anchoring because of the stronger radial force. She was discharged without any complication. Echocardiography at 3 months follow-up showed a well-functioning transcatheter heart valve (THV) without migration or paravalvular leakage.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>In our patient with non-calcified bicuspid AS, an SEV that was one size larger than the optimal as measured on CT was successfully implanted without THV embolization. An upsized SEV may be considered when performing TAVI in patients with severe non-calcified AS.<\/jats:p><\/jats:sec>","DOI":"10.1093\/ehjcr\/ytad048","type":"journal-article","created":{"date-parts":[[2023,1,30]],"date-time":"2023-01-30T21:20:49Z","timestamp":1675113649000},"source":"Crossref","is-referenced-by-count":1,"title":["Transcatheter aortic valve implantation for patient with non-calcified bicuspid aortic valve: a case report"],"prefix":"10.1093","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3832-8936","authenticated-orcid":false,"given":"Hideaki","family":"Nonaka","sequence":"first","affiliation":[{"name":"Division of Cardiology, Mitsui Memorial Hospital , Kanda-Izumicho 1, Chiyoda-ku, Tokyo 101-8643 , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2102-033X","authenticated-orcid":false,"given":"Masahiko","family":"Asami","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Mitsui Memorial Hospital , Kanda-Izumicho 1, Chiyoda-ku, Tokyo 101-8643 , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sumio","family":"Miura","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Mitsui Memorial Hospital , Tokyo , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kengo","family":"Tanabe","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Mitsui Memorial Hospital , Kanda-Izumicho 1, Chiyoda-ku, Tokyo 101-8643 , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2023,1,30]]},"reference":[{"key":"2023030116303598000_","doi-asserted-by":"crossref","first-page":"1854","DOI":"10.1016\/j.jacc.2012.02.093","article-title":"Calcific aortic stenosis: a disease of the valve and the myocardium","volume":"60","author":"Dweck","year":"2012","journal-title":"J Am Coll Cardiol"},{"key":"2023030116303598000_","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1002\/ccd.23275","article-title":"Incidence, timing, and predictors of valve dislodgment during TAVI with the Medtronic Corevalve System","volume":"79","author":"Van Mieghem","year":"2012","journal-title":"Catheter Cardiovasc Interv"},{"key":"2023030116303598000_","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1093\/ehjci\/jex006","article-title":"Severe aortic stenosis with low aortic valve calcification: characteristics and outcome following transcatheter aortic valve implantation","volume":"18","author":"Abramowitz","year":"2017","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"2023030116303598000_","doi-asserted-by":"crossref","first-page":"3166","DOI":"10.1093\/eurheartj\/ehz562","article-title":"Transcatheter heart valve migration and embolization: rare and preventable?","volume":"40","author":"Binder","year":"2019","journal-title":"Eur Heart J"},{"key":"2023030116303598000_","doi-asserted-by":"crossref","DOI":"10.3389\/fcvm.2021.743579","article-title":"TAVI For pure non-calcified aortic regurgitation using a self-expandable transcatheter heart valve","volume":"8","author":"Schneeberger","year":"2022","journal-title":"Front Cardiovasc Med"},{"key":"2023030116303598000_","doi-asserted-by":"crossref","first-page":"e007107","DOI":"10.1161\/CIRCINTERVENTIONS.118.007107","article-title":"Bicuspid aortic valve anatomy and relationship with devices: the BAVARD multicenter registry","volume":"12","author":"Tchetche","year":"2019","journal-title":"Circ Cardiovasc Interv"},{"key":"2023030116303598000_","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1002\/ccd.25830","article-title":"Comparison of multislice computed tomography findings between bicuspid and tricuspid aortic valves before and after transcatheter aortic valve implantation","volume":"86","author":"Watanabe","year":"2015","journal-title":"Catheter Cardiovasc Interv"},{"key":"2023030116303598000_","doi-asserted-by":"crossref","first-page":"E88","DOI":"10.1002\/ccd.25948","article-title":"Aortic annulus and root characteristics in severe aortic stenosis due to bicuspid aortic valve and tricuspid aortic valves: implications for transcatheter aortic valve therapies","volume":"86","author":"Philip","year":"2015","journal-title":"Catheter Cardiovasc Interv"},{"key":"2023030116303598000_","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1002\/ccd.25823","article-title":"Multicenter evaluation of transcatheter aortic valve replacement using either SAPIEN XT or CoreValve: degree of device oversizing by computed-tomography and clinical outcomes","volume":"86","author":"Dvir","year":"2015","journal-title":"Catheter Cardiovasc Interv"},{"key":"2023030116303598000_","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1007\/s00059-020-04973-5","article-title":"Treating patients with excessively large annuli with self-expanding transcatheter aortic valves: insights into supra-annular structures that anchor the prosthesis","volume":"46","author":"Xiong","year":"2021","journal-title":"Herz"},{"key":"2023030116303598000_","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.jcin.2017.10.014","article-title":"Early outcomes with the Evolut PRO repositionable self-expanding transcatheter aortic valve with pericardial wrap","volume":"11","author":"Forrest","year":"2018","journal-title":"JACC Cardiovasc Interv"},{"key":"2023030116303598000_","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.jcin.2019.08.041","article-title":"Transcatheter self-expandable valve implantation for aortic stenosis in small aortic annuli","volume":"13","author":"Regazzoli","year":"2020","journal-title":"JACC Cardiovasc Interv"}],"container-title":["European Heart Journal - Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ehjcr\/advance-article-pdf\/doi\/10.1093\/ehjcr\/ytad048\/48950633\/ytad048.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ehjcr\/article-pdf\/7\/2\/ytad048\/49229447\/ytad048.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ehjcr\/article-pdf\/7\/2\/ytad048\/49229447\/ytad048.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,23]],"date-time":"2023-03-23T07:08:22Z","timestamp":1679555302000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ehjcr\/article\/doi\/10.1093\/ehjcr\/ytad048\/7009177"}},"subtitle":[],"editor":[{"given":"Poonam","family":"Velagapudi","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Josip andelo","family":"Borovac","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Roman","family":"Gottardi","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Amr","family":"Idris","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Andreas","family":"Mitsis","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Nikolaos","family":"Spinthakis","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Lynsey","family":"Hewitson","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2023,1,30]]},"references-count":12,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,2,3]]}},"URL":"https:\/\/doi.org\/10.1093\/ehjcr\/ytad048","relation":{},"ISSN":["2514-2119"],"issn-type":[{"type":"electronic","value":"2514-2119"}],"subject":[],"published-other":{"date-parts":[[2023,2,1]]},"published":{"date-parts":[[2023,1,30]]},"article-number":"ytad048"}}