{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T07:24:00Z","timestamp":1793777040011,"version":"4.6.1"},"reference-count":17,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2023,2,28]],"date-time":"2023-02-28T00:00:00Z","timestamp":1677542400000},"content-version":"vor","delay-in-days":28,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,2,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Dilated cardiomyopathy (DCM) is a leading cause of heart transplantation (HTx) in children. Surgical pulmonary artery banding (PAB) is used worldwide to achieve functional heart regeneration and remodelling.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case summary<\/jats:title><jats:p>We report for the first-time successful bilateral transcatheter implantation of bilateral pulmonary artery flow restrictors in a case series of three infants with severe DCM based on left-ventricular non-compaction morphology associated with Barth syndrome in one and a non-classified syndrome in another. Functional cardiac regeneration was observed in two patients after almost 6 months of endoluminal banding, and in the neonate with Barth syndrome already after 6 weeks. Accompanied by an improvement in functional class (Class IV to Class I), the left ventricular end-diastolic dimensions z-score normalized, as did the elevated serum brain natriuretic peptide levels. A listing for HTx could be avoided.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Percutaneous bilateral endoluminal PAB is a novel minimally invasive approach that enables functional cardiac regeneration in infants with severe DCM and preserved right ventricular function. Interruption of the ventriculo-ventricular interaction, the key mechanism for recovery, is avoided. Intensive care for these critically ill patients is reduced to a minimum. However, investing in \u2018heart regeneration to avoid transplantation\u2019 remains a challenge.<\/jats:p><\/jats:sec>","DOI":"10.1093\/ehjcr\/ytad052","type":"journal-article","created":{"date-parts":[[2023,1,31]],"date-time":"2023-01-31T09:43:36Z","timestamp":1675158216000},"source":"Crossref","is-referenced-by-count":11,"title":["Functional regeneration of dilated cardiomyopathy by transcatheter bilateral pulmonary artery banding: first-in-human case series"],"prefix":"10.1093","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4559-9021","authenticated-orcid":false,"given":"Dietmar","family":"Schranz","sequence":"first","affiliation":[{"name":"Pediatric Cardiology, Children\u2019s Hospital, Johann Wolfgang Goethe University , Theodor-Stern-Kai 7, Frankfurt D-60596 , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3673-165X","authenticated-orcid":false,"given":"Ulrich","family":"Krause","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology, Georg-August-University Medical Center , G\u00f6ttingen , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gunter","family":"Kerst","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology, University Hospital RWTH Aachen , Aachen , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8075-1060","authenticated-orcid":false,"given":"Anoosh","family":"Esmaeili","sequence":"additional","affiliation":[{"name":"Pediatric Cardiology, Children\u2019s Hospital, Johann Wolfgang Goethe University , Theodor-Stern-Kai 7, Frankfurt D-60596 , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Paul","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology, Georg-August-University Medical Center , G\u00f6ttingen , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,1,31]]},"reference":[{"key":"2023030116314786200_","first-page":"1867","article-title":"Incidence, causes, and outcome of dilated cardiomyopathy in children","volume":"296","author":"Towbin","year":"2006","journal-title":"JAMA Cardiol"},{"key":"2023030116314786200_","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1016\/j.jtcvs.2007.04.044","article-title":"Pulmonary artery banding for idiopathic dilative cardiomyopathy: a novel therapeutic strategy using an old surgical procedure","volume":"134","author":"Schranz","year":"2007","journal-title":"J Thorac Cardiovasc 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