{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T11:50:08Z","timestamp":1753876208192,"version":"3.41.2"},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2023,3,3]],"date-time":"2023-03-03T00:00:00Z","timestamp":1677801600000},"content-version":"vor","delay-in-days":2,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,3,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Lemierre\u2019s syndrome is an infectious phenomenon characterized by oropharyngeal infection with bacteraemia, thrombophlebitis, and distant septic emboli. Septic emboli are a recognized cause of a Type 2 myocardial infarction, with a left ventricular pseudoaneurysm being a rare but important complication of this.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case summary<\/jats:title><jats:p>A 19-year-old male presented with acute confusion, fevers, and a cough. Blood cultures were positive for Fusobacterium necrophorum and initial imaging showed a cavitating pneumonia. Further evaluation revealed septic emboli in the distal digits and brain. The patient initially responded to antibiotic therapy but developed chest pain with increased troponin levels. An electrocardiogram showed inferolateral ST elevation. A transthoracic echocardiogram (TTE) showed hypokinaesia of the mid to apical lateral wall, and a computed tomography (CT) scan showed a pericardial effusion with a possible purulent effusion or abscess. The patient underwent surgical drainage of a sterile effusion. A post-operative TTE and CT demonstrated a left ventricular pseudoaneurysm that was surgically repaired. The venous thrombus was encountered intra-operatively confirming a diagnosis of Lemierre\u2019s syndrome. The patient completed the regimen of antibiotics and showed a good post-operative recovery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>This is the first case described of left ventricular pseudoaneurysm as a complication of Lemierre\u2019s syndrome. It highlights not only the importance of serial, multimodality imaging in both diagnostic workup and identification of complications, but also the importance of a multidisciplinary team in the management of patients with complex and rare presentations.<\/jats:p><\/jats:sec>","DOI":"10.1093\/ehjcr\/ytad109","type":"journal-article","created":{"date-parts":[[2023,3,4]],"date-time":"2023-03-04T09:46:52Z","timestamp":1677923212000},"source":"Crossref","is-referenced-by-count":0,"title":["Left ventricular pseudoaneurysm in Lemierre\u2019s syndrome: a case report"],"prefix":"10.1093","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7700-3400","authenticated-orcid":false,"given":"Alexander","family":"Gall","sequence":"first","affiliation":[{"name":"Cardiology Department, Gloucester Royal Hospital , Great Western Road, Gloucester GL1 3NN , UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manraj Singh","family":"Sandhu","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Bristol Heart Institute , Terrell Street, Bristol BS2 8ED , UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eltayeb Mohamed","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Bristol Heart Institute , Terrell Street, Bristol BS2 8ED , UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher James","family":"McAloon","sequence":"additional","affiliation":[{"name":"Cardiology Department, Gloucester Royal Hospital , Great Western Road, Gloucester GL1 3NN , UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2023,3,3]]},"reference":[{"key":"2023032214570562800_","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/j.jmii.2020.03.027","article-title":"Lemierre\u2019s syndrome: a forgotten and re-emerging infection","volume":"53","author":"Sen","year":"2020","journal-title":"J Microbiol Immunol Infect"},{"key":"2023032214570562800_","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1093\/eurheartj\/ehy462","article-title":"Fourth universal definition of myocardial infarction (2018)","volume":"40","author":"Thygesen","year":"2019","journal-title":"Eur Heart J"},{"key":"2023032214570562800_","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1001\/jamacardio.2020.3690","article-title":"Mechanical complications of acute myocardial infarction: a review","volume":"6","author":"Gong","year":"2021","journal-title":"JAMA Cardiol"},{"key":"2023032214570562800_","first-page":"47","article-title":"Surgical treatment of post-infarction left ventricular pseudoaneurysm clinical investigation","volume":"34","author":"Eren","year":"2007","journal-title":"Tex Heart Inst J"},{"key":"2023032214570562800_","doi-asserted-by":"crossref","first-page":"801511","DOI":"10.3389\/fcvm.2022.801511","article-title":"Surgical and conservative treatment of post-infarction left ventricular pseudoaneurysm","volume":"9","author":"Zhong","year":"2022","journal-title":"Front Cardiovasc Med"},{"volume-title":"Statpearls","year":"2022","author":"Brown","key":"2023032214570562800_"},{"key":"2023032214570562800_","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1865-1380-6-40","article-title":"Lemierre\u2019s syndrome","volume":"6","author":"Eilbert","year":"2013","journal-title":"Int J Emerg Med"},{"key":"2023032214570562800_","doi-asserted-by":"crossref","first-page":"e379","DOI":"10.1055\/s-0039-3402433","article-title":"Lemierre syndrome: a meta-analysis","volume":"24","author":"Gore","year":"2020","journal-title":"Int Arch Otorhinolaryngol"},{"key":"2023032214570562800_","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/ofid\/ofaa585","article-title":"Jugular vein thrombosis and anticoagulation therapy in Lemierre\u2019s syndrome - a post hoc observational and population-based study of 82 patients","volume":"8","author":"Nygren","year":"2021","journal-title":"Open Forum Infect Dis"},{"key":"2023032214570562800_","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1111\/joim.13114","article-title":"Patients with Lemierre syndrome have a high risk of new thromboembolic complications, clinical sequelae and death: an analysis of 712 cases","volume":"289","author":"Valerio","year":"2021","journal-title":"J Intern Med"},{"key":"2023032214570562800_","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1055\/s-0038-1654720","article-title":"Lemierre syndrome: clinical update and protocol for a systematic review and individual patient data meta-analysis","volume":"39","author":"Sacco","year":"2019","journal-title":"Hamostaseologie"},{"key":"2023032214570562800_","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1159\/000452855","article-title":"Lemierre syndrome: a retrospective study of the role of anticoagulation and thrombosis outcomes","volume":"137","author":"Cupit-Link","year":"2017","journal-title":"Acta Haematol"}],"container-title":["European Heart Journal - Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ehjcr\/advance-article-pdf\/doi\/10.1093\/ehjcr\/ytad109\/49410316\/ytad109.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ehjcr\/article-pdf\/7\/3\/ytad109\/49593792\/ytad109.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ehjcr\/article-pdf\/7\/3\/ytad109\/49593792\/ytad109.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,27]],"date-time":"2023-03-27T13:12:57Z","timestamp":1679922777000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ehjcr\/article\/doi\/10.1093\/ehjcr\/ytad109\/7068294"}},"subtitle":[],"editor":[{"given":"Amardeep Ghosh","family":"Dastidar","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Omar","family":"Abdelfattah","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Damien Farhad Nur","family":"Salekin","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2023,3,1]]},"references-count":12,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,3,6]]}},"URL":"https:\/\/doi.org\/10.1093\/ehjcr\/ytad109","relation":{},"ISSN":["2514-2119"],"issn-type":[{"type":"electronic","value":"2514-2119"}],"subject":[],"published-other":{"date-parts":[[2023,3,1]]},"published":{"date-parts":[[2023,3,1]]},"article-number":"ytad109"}}