{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T11:33:20Z","timestamp":1774611200095,"version":"3.50.1"},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2023,3,29]],"date-time":"2023-03-29T00:00:00Z","timestamp":1680048000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,4,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>SARS-CoV-2 has been implicated in many cardiac pathologies, manifesting mainly as acute. However, acute purulent pericarditis is exceedingly rare in the antibiotic era. Though, few studies have associated it with long-COVID, prompt recognition and treatment are crucial.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case summary<\/jats:title>\n                  <jats:p>A 61-year-old immunocompetent woman presented with a left lower limb pitting oedema 1 month after COVID-19 pneumonia. Following clinical, laboratory, and imaging work-up, the patient was found to have deep vein thrombosis of the anterior and posterior tibial and gastrocnemius veins. Owning to persistent sinus tachycardia, an additional work-up was performed, which revealed a large pericardial effusion. Pericardiocentesis drained the frank pus, and subsequently, empirical antibiotics therapy was initiated. Pericardial fluid cultures showed methicillin-sensitive Staphylococcus aureus (MSSA). Following the antibiotic treatment with cloxacillin 6 \u00d7 2\u2005g IV for 6 weeks, the patient fully recovered.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>Herein, we report a rare case of bacterial pericarditis caused by MSSA 1 month after COVID-19 pneumonia. Additionally, this condition may arise as a result of immunosuppressive treatment with glucocorticoids during and after COVID-19 pneumonia. However, the causal association has not yet been confirmed.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytad141","type":"journal-article","created":{"date-parts":[[2023,3,30]],"date-time":"2023-03-30T15:50:31Z","timestamp":1680191431000},"source":"Crossref","is-referenced-by-count":4,"title":["Purulent pericarditis caused by methicillin-sensitive <i>Staphylococcus aureus<\/i> in an immunocompetent adult after COVID-19 pneumonia: a case report"],"prefix":"10.1093","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1845-4871","authenticated-orcid":false,"given":"Tea-Terezija","family":"Cvetko","sequence":"first","affiliation":[{"name":"Department of cardiology, County Hospital Cakovec , I.G, Kovacica 1e, 40000 Cakovec , Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6151-3702","authenticated-orcid":false,"given":"Jelena","family":"Ljubic","sequence":"additional","affiliation":[{"name":"Department of cardiology, County Hospital Cakovec , I.G, Kovacica 1e, 40000 Cakovec , Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8682-5158","authenticated-orcid":false,"given":"Branko","family":"Ostricki","sequence":"additional","affiliation":[{"name":"Department of cardiology, County Hospital Cakovec , I.G, Kovacica 1e, 40000 Cakovec , Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2023,3,29]]},"reference":[{"key":"2023042021432180800_ytad141-B1","doi-asserted-by":"crossref","first-page":"693","DOI":"10.2459\/JCM.0000000000001202","article-title":"Pericarditis in patients with COVID-19: a systematic review","volume":"22","author":"Diaz-Arocutipa","year":"2021","journal-title":"J Cardiovasc Med (Hagerstown)"},{"key":"2023042021432180800_ytad141-B2","doi-asserted-by":"crossref","first-page":"1997","DOI":"10.3390\/v13101997","article-title":"Pericarditis after SARS-CoV-2 infection: another pebble in the mosaic of long COVID?","volume":"13","author":"Carubbi","year":"2021","journal-title":"Viruses"},{"key":"2023042021432180800_ytad141-B3","doi-asserted-by":"crossref","first-page":"110345","DOI":"10.1016\/j.mehy.2020.110345","article-title":"The triggering of post-COVID-19 autoimmunity phenomena could be associated with both transient immunosuppression and an inappropriate form of immune reconstitution in susceptible individuals","volume":"145","author":"Ca\u00f1as","year":"2020","journal-title":"Med Hypotheses"},{"key":"2023042021432180800_ytad141-B4","doi-asserted-by":"crossref","first-page":"2921","DOI":"10.1093\/eurheartj\/ehv318","article-title":"ESC Scientific document group. 2015 ESC guidelines for the diagnosis and management of pericardial diseases: the task force for the diagnosis and management of pericardial diseases of the European Society of Cardiology (ESC) endorsed by: the European Association for Cardio-Thoracic Surgery (EACTS)","volume":"36","author":"Adler","year":"2015","journal-title":"Eur Heart J"},{"key":"2023042021432180800_ytad141-B5","article-title":"Staphylococcal pericarditis causing pericardial tamponade and concurrent empyema","volume":"2019","author":"Kondapi","year":"2019","journal-title":"Case Rep Infect Dis"},{"key":"2023042021432180800_ytad141-B6","doi-asserted-by":"crossref","first-page":"484","DOI":"10.11622\/smedj.2021022","article-title":"A case of acute bacterial pericarditis in a COVID-19 patient","volume":"63","author":"Lee","year":"2021","journal-title":"Singapore Med J"},{"key":"2023042021432180800_ytad141-B7","doi-asserted-by":"crossref","first-page":"e13679","DOI":"10.1111\/eci.13679","article-title":"Prevalence and clinical outcomes of myocarditis and pericarditis in 718,365 COVID-19 patients","volume":"51","author":"Buckley","year":"2021","journal-title":"Eur J Clin Invest"},{"key":"2023042021432180800_ytad141-B8","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1161\/CIRCULATIONAHA.120.051362","article-title":"Urgent need for studies of the late effects of SARS-CoV-2 on the cardiovascular system","volume":"143","author":"Maleszewski","year":"2021","journal-title":"Circulation"}],"container-title":["European Heart Journal - 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