{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T11:50:12Z","timestamp":1753876212623,"version":"3.41.2"},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2023,4,5]],"date-time":"2023-04-05T00:00:00Z","timestamp":1680652800000},"content-version":"vor","delay-in-days":4,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,4,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Atrial fibrillation (AF) is a well-established risk factor for intracardiac thrombosis. Left atrial appendage occlusion (LAAO) is emerging as a viable alternative to oral anticoagulation (OAC) for high-risk AF patients who are contraindicated to long-term OAC.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case summary<\/jats:title>\n                  <jats:p>A 74-year-old man with a history of permanent AF and subdural haemorrhage on warfarin therapy was referred to our facility for further management. Cardiac CT imaging revealed large bi-atrial thrombi for which apixaban therapy was initiated. Serial imaging over nine months showed gradual shrinkage and then resolution of the thrombi. In line with the patient\u2019s preference to avoid life-long OAC, he received LAAO using an Amplatzer\u2122 Amulet\u2122 device. Follow-up transoesophageal echocardiography showed a well-seated device with no leak and no thrombus.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>We discussed the key issues surrounding management of bi-atrial thrombi and the decision to perform LAAO in these circumstances, relying on shared decision making and multi-disciplinary team input.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytad165","type":"journal-article","created":{"date-parts":[[2023,4,5]],"date-time":"2023-04-05T14:22:36Z","timestamp":1680704556000},"source":"Crossref","is-referenced-by-count":0,"title":["Percutaneous left atrial appendage occlusion following successful treatment of large bi-atrial thrombi in a patient with atrial fibrillation: a case report"],"prefix":"10.1093","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5306-2622","authenticated-orcid":false,"given":"Kim Fong","family":"Ng","sequence":"first","affiliation":[{"name":"Department of Cardiology, Liverpool Heart & Chest Hospital , Thomas Drive, Liverpool L14 3PE , UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8401-4033","authenticated-orcid":false,"given":"Peter","family":"Calvert","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Liverpool Heart & Chest Hospital , Thomas Drive, Liverpool L14 3PE , UK"},{"name":"Liverpool Centre for Cardiovascular Science, University of Liverpool , William Henry Duncan Building, 6 W Derby Street, Liverpool, L7 8TX , UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Afshin","family":"Khalatbari","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Liverpool Heart & Chest Hospital , Thomas Drive, Liverpool L14 3PE , UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7566-1626","authenticated-orcid":false,"given":"Gregory Y H","family":"Lip","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Liverpool Heart & Chest Hospital , Thomas Drive, Liverpool L14 3PE , UK"},{"name":"Liverpool Centre for Cardiovascular Science, University of Liverpool , William Henry Duncan Building, 6 W Derby Street, Liverpool, L7 8TX , UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Periaswamy","family":"Velavan","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Liverpool Heart & Chest Hospital , Thomas Drive, Liverpool L14 3PE , UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dhiraj","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Liverpool Heart & Chest Hospital , Thomas Drive, Liverpool L14 3PE , UK"},{"name":"Liverpool Centre for Cardiovascular 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