{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T05:23:55Z","timestamp":1783229035452,"version":"3.54.6"},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2023,4,17]],"date-time":"2023-04-17T00:00:00Z","timestamp":1681689600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,5,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>To date, no information is available on highly localized impedance (LI) measurements during the ablation of pulmonary veins (PVs) via a new form of energy such as electroporation by means of pulsed-field ablation (PFA).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case summary<\/jats:title>\n                  <jats:p>A 55-year-old man with a history of paroxysmal atrial fibrillation was admitted to our hospital for PV isolation (PVI). The procedure was performed with the new multi-electrode PFA catheter (FARAWAVE\u2122). Before energy delivery, a high-density map of the left atrium was constructed with the Rhythmia\u2122 system, while the IntellaNAV Mifi\u2122 OI catheter was used to assess the baseline LI values of the four PVs. A manual tag was used to record the exact position where the IntellaNAV\u2122 catheter measured the LI values for each segment of the vein before and after PVI. The LI values displayed a significant variation after PFA delivery (124.3 \u00b1 5\u2005\u2126 for baseline LI vs. 96.8 \u00b1 6\u2005\u2126 after PFA, P &amp;lt; 0.0001) with a mean absolute LI variation of 27.5 \u00b1 7\u2126 and a mean percentage LI variation of 25.8 \u00b1 8%. The differences between the average LI values pre- and post-PFA were 28.0 \u00b1 5, 26.5 \u00b1 9, 26.8 \u00b1 3, and 28.8 \u00b1 10\u2005\u2126 for the superior, anterior, posterior, and inferior portions of the PV.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>This is the first instance of the acute characterization, in terms of LI drop, of antral lesions created by a new PFA system. Local impedance variations at ablation sites seem to be larger than those recorded at successful ablation spots obtained by means of thermal energy sources.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytad187","type":"journal-article","created":{"date-parts":[[2023,4,17]],"date-time":"2023-04-17T15:06:28Z","timestamp":1681743988000},"source":"Crossref","is-referenced-by-count":4,"title":["Lesion effects in terms of local impedance variations after pulsed-field ablation during pulmonary vein isolation: a case report"],"prefix":"10.1093","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2131-1110","authenticated-orcid":false,"given":"Saverio","family":"Iacopino","sequence":"first","affiliation":[{"name":"Electrophysiology Unit, GVM Care and Research, Maria Cecilia Hospital , Cotignola, RA , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gennaro","family":"Fabiano","sequence":"additional","affiliation":[{"name":"Electrophysiology Unit, GVM Care and Research, Maria Cecilia Hospital , Cotignola, RA , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurizio","family":"Malacrida","sequence":"additional","affiliation":[{"name":"Medical Education & Scientific Affairs , Boston Scientific, Milan , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Petretta","sequence":"additional","affiliation":[{"name":"Electrophysiology Unit, GVM Care and Research, Maria Cecilia Hospital , Cotignola, RA , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,4,17]]},"reference":[{"key":"2023050819060651900_ytad187-B1","first-page":"e1","article-title":"HRS\/EHRA\/ECAS\/APHRS\/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation","volume":"2018","author":"Calkins","year":"2017","journal-title":"Europace"},{"key":"2023050819060651900_ytad187-B2","doi-asserted-by":"crossref","first-page":"1793","DOI":"10.1007\/s00216-004-2508-2","article-title":"Using electrical impedance detection to evaluate the viability of biomaterials subject to freezing or thermal injury","volume":"378","author":"Yu","year":"2004","journal-title":"Anal Bioanal Chem"},{"key":"2023050819060651900_ytad187-B3","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.1111\/jce.15041","article-title":"Pulmonary vein isolation in atrial fibrillation patients guided by a novel local impedance algorithm: 1-year outcome from the CHARISMA study","volume":"32","author":"Solimene","year":"2021","journal-title":"J Cardiovasc Electrophysiol"},{"key":"2023050819060651900_ytad187-B4","doi-asserted-by":"crossref","first-page":"i34","DOI":"10.1093\/europace\/euy273","article-title":"A novel assessment of local impedance during catheter ablation: initial experience in humans comparing local and generator measurements","volume":"21","author":"Gunawardene","year":"2019","journal-title":"Europace"},{"key":"2023050819060651900_ytad187-B5","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.hrcr.2020.12.007","article-title":"Antral lesion characterization of a new cryoballoon ablation system in terms of local impedance drop: the first reported case","volume":"7","author":"Iacopino","year":"2020","journal-title":"HeartRhythm Case Rep"},{"key":"2023050819060651900_ytad187-B6","doi-asserted-by":"crossref","first-page":"ii44","DOI":"10.1093\/europace\/euab258","article-title":"New energy sources and technologies for atrial fibrillation catheter ablation","volume":"24","author":"Boersma","year":"2022","journal-title":"Europace"},{"key":"2023050819060651900_ytad187-B7","doi-asserted-by":"crossref","first-page":"719","DOI":"10.3390\/jcm12020719","article-title":"Efficacy and safety of pulsed field ablation in atrial fibrillation: a systematic review","volume":"12","author":"Shtembari","year":"2023","journal-title":"J Clin Med"},{"key":"2023050819060651900_ytad187-B8","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1093\/europace\/euac044","article-title":"Validation of a multipolar pulsed-field ablation catheter for endpoint assessment in pulmonary vein isolation procedures","volume":"24","author":"Kueffer","year":"2022","journal-title":"Europace"}],"container-title":["European Heart Journal - Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ehjcr\/advance-article-pdf\/doi\/10.1093\/ehjcr\/ytad187\/49992171\/ytad187.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ehjcr\/article-pdf\/7\/5\/ytad187\/50248659\/ytad187.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ehjcr\/article-pdf\/7\/5\/ytad187\/50248659\/ytad187.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,8]],"date-time":"2023-05-08T19:06:36Z","timestamp":1683572796000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ehjcr\/article\/doi\/10.1093\/ehjcr\/ytad187\/7126626"}},"subtitle":[],"editor":[{"given":"Fabian","family":"Barbieri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"Philipp","family":"Sommer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"Linh","family":"Ngo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"Pok-Tin","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"Niklas","family":"Schenker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2023,4,17]]},"references-count":8,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,5,2]]}},"URL":"https:\/\/doi.org\/10.1093\/ehjcr\/ytad187","relation":{},"ISSN":["2514-2119"],"issn-type":[{"value":"2514-2119","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,5]]},"published":{"date-parts":[[2023,4,17]]},"article-number":"ytad187"}}