{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,8]],"date-time":"2025-12-08T22:38:43Z","timestamp":1765233523288,"version":"3.41.2"},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2023,4,25]],"date-time":"2023-04-25T00:00:00Z","timestamp":1682380800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,5,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Concerns on monkeypox as a disease impacting global public health first emerged in May, 2022, and, since that time, has been identified in more than 50 countries. The condition mainly affects men who have sex with other men. Cardiac disease is a rare complication of monkeypox infection. Here, we describe a case of myocarditis in a young male subsequently diagnosed with monkeypox infection.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case summary<\/jats:title>\n                  <jats:p>A 42-year-old male reported engaging in high-risk sexual behaviours with another male 10 days before presenting to the emergency department with chest pain, fever, maculopapular rash, and a necrotic chin lesion. Electrocardiography revealed diffuse concave ST-segment elevation associated with elevated cardiac biomarkers. Transthoracic echocardiography revealed normal biventricular systolic function without wall motion abnormalities. We excluded other sexually transmitted diseases or viral infections. Cardiac magnetic resonance imaging (MRI) findings suggested myopericarditis involving the lateral wall and adjacent pericardium. The results of polymerase chain reaction (PCR) tests of pharyngeal, urethral, and blood samples were positive for monkeypox. The patient was treated with high-dose non-steroidal anti-inflammatory drugs (NSAIDs) and colchicine and he recovered soon.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>Monkeypox infections are generally self-limited, with most patients experiencing benign clinical outcomes, no hospitalizations, and few complications. This is a rare report of monkeypox complicated with myopericarditis. Management with high-dose NSAIDs and colchicine relieved our patient\u2019s symptoms, suggesting a similar clinical outcome as other idiopathic or virus-related myopericarditis.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytad211","type":"journal-article","created":{"date-parts":[[2023,4,25]],"date-time":"2023-04-25T20:40:45Z","timestamp":1682455245000},"source":"Crossref","is-referenced-by-count":4,"title":["Myocarditis in a young male affected with monkeypox infection: a case report"],"prefix":"10.1093","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7035-386X","authenticated-orcid":false,"given":"Sergio","family":"Luengo P\u00e9rez","sequence":"first","affiliation":[{"name":"Department of Cardiology, Hospital General Universitario de Valencia , Avenida Tres Cruces 2, Valencia 46014 , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0437-3384","authenticated-orcid":false,"given":"Juli\u00e1n","family":"Abdala Lizarraga","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Hospital General Universitario de Valencia , Avenida Tres Cruces 2, Valencia 46014 , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-9466-0492","authenticated-orcid":false,"given":"Esther","family":"Ja\u00e9n Ferrer","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Hospital General Universitario de Valencia, Avenida Tres Cruces 2 , Valencia 46014 , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco","family":"Ridocci Soriano","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Hospital General Universitario de Valencia , Avenida Tres Cruces 2, Valencia 46014 , Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2023,4,25]]},"reference":[{"key":"2023051009475528300_ytad211-B1","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/S0140-6736(22)01436-2","article-title":"Clinical presentation and virological assessment of confirmed human monkeypox virus cases in Spain: a prospective observational cohort study","volume":"400","author":"Tar\u00edn-Vicente","year":"2022","journal-title":"Lancet"},{"key":"2023051009475528300_ytad211-B2","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1056\/NEJMoa2207323","article-title":"Monkeypox virus infection in humans across 16 countries\u2014April\u2013June 2022","volume":"387","author":"Thornhill","year":"2022","journal-title":"N Engl J Med"},{"key":"2023051009475528300_ytad211-B3","doi-asserted-by":"crossref","first-page":"2508","DOI":"10.3201\/eid2812.221276","article-title":"Myocarditis attributable to monkeypox virus infection in 2 patients, United States, 2022","volume":"28","author":"Rodriguez-Nava","year":"2022","journal-title":"Emerg Infect Dis"},{"key":"2023051009475528300_ytad211-B4","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0010141","article-title":"The changing epidemiology of human monkeypox\u2014a potential threat? A systematic review","volume":"16","author":"Bunge","year":"2022","journal-title":"PLoS Negl Trop Dis"},{"author":"WHO Health Emergency Dashboard","key":"2023051009475528300_ytad211-B5"},{"key":"2023051009475528300_ytad211-B6","doi-asserted-by":"crossref","first-page":"4758","DOI":"10.1016\/j.vaccine.2014.06.034","article-title":"Ischemic cardiac events and other adverse events following ACAM2000\u00ae smallpox vaccine in the Vaccine Adverse Event Reporting System","volume":"32","author":"McNeil","year":"2014","journal-title":"Vaccine"},{"key":"2023051009475528300_ytad211-B7","doi-asserted-by":"crossref","first-page":"e80","DOI":"10.1016\/S1473-3099(20)30130-4","article-title":"The state of vaccine safety science: systematic reviews of the evidence","volume":"20","author":"Dudley","year":"2020","journal-title":"Lancet Infect Dis"},{"key":"2023051009475528300_ytad211-B8","doi-asserted-by":"crossref","first-page":"71","DOI":"10.2147\/DDDT.S3687","article-title":"ACAM2000: the new smallpox vaccine for United States Strategic National Stockpile","volume":"4","author":"Nalca","year":"2010","journal-title":"Drug Des Dev Ther"}],"container-title":["European Heart Journal - Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ehjcr\/advance-article-pdf\/doi\/10.1093\/ehjcr\/ytad211\/50095671\/ytad211.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ehjcr\/article-pdf\/7\/5\/ytad211\/50262656\/ytad211.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ehjcr\/article-pdf\/7\/5\/ytad211\/50262656\/ytad211.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,11]],"date-time":"2023-05-11T04:05:01Z","timestamp":1683777901000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ehjcr\/article\/doi\/10.1093\/ehjcr\/ytad211\/7142718"}},"subtitle":[],"editor":[{"given":"Sadaf","family":"Raza","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Mark","family":"Abela","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Matthew","family":"Williams","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Nikolaos","family":"Spinthakis","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Nikesh","family":"Jathanna","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2023,4,25]]},"references-count":8,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,5,2]]}},"URL":"https:\/\/doi.org\/10.1093\/ehjcr\/ytad211","relation":{},"ISSN":["2514-2119"],"issn-type":[{"type":"electronic","value":"2514-2119"}],"subject":[],"published-other":{"date-parts":[[2023,5]]},"published":{"date-parts":[[2023,4,25]]},"article-number":"ytad211"}}