{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T18:50:08Z","timestamp":1778007008007,"version":"3.51.4"},"reference-count":6,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2023,5,19]],"date-time":"2023-05-19T00:00:00Z","timestamp":1684454400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,6,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Atrioventricular valve regurgitation (AVVR) is present in up to 75% of Fontan patients, and it is associated with an increased risk of Fontan circulation failure, morbidity, and mortality. Traditional treatment options include surgical repair vs. surgical replacement. We present, to the best of our knowledge, one of the first cases of successful trans-catheter repair of severe common AVVR using the MitraClip device.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case summary<\/jats:title>\n                  <jats:p>A 20-year-old male with a history of double-outlet right ventricle (DORV) with unbalanced common atrioventricular canal to the right ventricle, severely hypoplastic left ventricle, and total anomalous pulmonary venous return status post-Fontan procedure presented with progressively worsening dyspnoea on exertion. Transoesophageal echocardiogram demonstrated severe common AVVR. After discussion of the case during the adult congenital heart disease multidisciplinary conference, patient underwent successful placement of two MitraClip devices, reducing the regurgitation from torrential to moderate.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>MitraClip therapy can be used to alleviate symptoms in patients deemed as high risk for surgery. However, careful attention must be paid to haemodynamics before and after clip placement, which may predict short-term clinical outcomes.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ehjcr\/ytad247","type":"journal-article","created":{"date-parts":[[2023,5,20]],"date-time":"2023-05-20T00:48:31Z","timestamp":1684543711000},"source":"Crossref","is-referenced-by-count":5,"title":["A case report of percutaneous MitraClip implantation in an adult with a double-outlet right ventricle"],"prefix":"10.1093","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0582-5867","authenticated-orcid":false,"given":"Preetham","family":"Kumar","sequence":"first","affiliation":[{"name":"Division of Cardiology, Department of Medicine, University of California, Riverside , 900 University Ave, Riverside, CA 92521 , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brent M","family":"Gordon","sequence":"additional","affiliation":[{"name":"Division of Pediatric Cardiology, Department of Pediatrics, Loma Linda University Children\u2019s Hospital , Loma Linda, CA , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed","family":"Kheiwa","sequence":"additional","affiliation":[{"name":"Division of Pediatric Cardiology, Department of Pediatrics, Loma Linda University Children\u2019s Hospital , Loma Linda, CA , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Islam","family":"Abudayyeh","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine, Loma Linda University Medical Center , Loma Linda, CA , USA"},{"name":"Section of Cardiology, Department of Medicine, Veterans Administration Loma Linda Healthcare System , Loma Linda, CA , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2023,5,19]]},"reference":[{"key":"2023060914130401600_ytad247-B1","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1016\/j.jacc.2018.12.025","article-title":"Atrioventricular valve failure in Fontan palliation","volume":"73","author":"King","year":"2019","journal-title":"J Am Coll Cardiol"},{"key":"2023060914130401600_ytad247-B2","first-page":"221","article-title":"Transcatheter edge-to-edge repair of systemic tricuspid valve in extracardiac fontan circulation: first in human","volume":"4","author":"Blusztein","year":"2022","journal-title":"J Am Coll Cardiol Case Rep"},{"key":"2023060914130401600_ytad247-B3","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.122.025628","article-title":"Percutaneous edge-to-edge repair for systemic atrioventricular valve regurgitation in patients with congenital heart disease: the first descriptive cohort","volume":"11","author":"Guerin","year":"2022","journal-title":"JAHA"},{"key":"2023060914130401600_ytad247-B4","doi-asserted-by":"crossref","first-page":"2580","DOI":"10.1016\/j.jtcvs.2014.08.005","article-title":"Increased common atrioventricular valve tenting is a risk factor for progression to severe regurgitation in patients with a single ventricle with unbalanced atrioventricular septal defect","volume":"148","author":"Vijarnsorn","year":"2014","journal-title":"J Thor Cardiovascr Surg"},{"key":"2023060914130401600_ytad247-B5","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1093\/ejcts\/ezu489","article-title":"Results of Fontan operation in patients with atrioventricular valve regurgitation","volume":"48","author":"Podzolkov","year":"2015","journal-title":"Eur J Cardiothorac Surg"},{"key":"2023060914130401600_ytad247-B6","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1016\/j.jacc.2009.03.077","article-title":"Percutaneous mitral repair with the MitraClip system","volume":"54","author":"Feldman","year":"2009","journal-title":"J Am Coll Cardiol"}],"container-title":["European Heart Journal - Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ehjcr\/advance-article-pdf\/doi\/10.1093\/ehjcr\/ytad247\/50401932\/ytad247.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ehjcr\/article-pdf\/7\/6\/ytad247\/50516218\/ytad247.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ehjcr\/article-pdf\/7\/6\/ytad247\/50516218\/ytad247.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,9]],"date-time":"2023-06-09T15:53:11Z","timestamp":1686325991000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ehjcr\/article\/doi\/10.1093\/ehjcr\/ytad247\/7174119"}},"subtitle":[],"editor":[{"given":"Anastasia","family":"Egorova","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"David","family":"Blusztein","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"A Shaheer","family":"Ahmed","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Sara","family":"Monosilio","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]},{"given":"Gon\u00e7alo","family":"Costa","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2023,5,19]]},"references-count":6,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,6,2]]}},"URL":"https:\/\/doi.org\/10.1093\/ehjcr\/ytad247","relation":{},"ISSN":["2514-2119"],"issn-type":[{"value":"2514-2119","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,6]]},"published":{"date-parts":[[2023,5,19]]},"article-number":"ytad247"}}